Ribosyldihydronicotinamide dehydrogenase (quinone)

From Wikipedia, the free encyclopedia
Jump to: navigation, search
dihydronicotinamide riboside quinone reductase
Identifiers
EC number 1.10.99.2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a ribosyldihydronicotinamide dehydrogenase (quinone) (EC 1.10.99.2) is an enzyme that catalyzes the chemical reaction

1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone

Thus, the two substrates of this enzyme are 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide and quinone, whereas its two products are 1-(beta-D-ribofuranosyl)nicotinamide and hydroquinone.

This enzyme belongs to the family of oxidoreductases, specifically those acting on diphenols and related substances as donor with other acceptors, the systematic name of this enzyme class is 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide:quinone oxidoreductase. Other names in common use include NRH:quinone oxidoreductase 2, NQO2, NQO2, NAD(P)H:quinone oxidoreductase-2 (misleading), QR2, quinone reductase 2, N-ribosyldihydronicotinamide dehydrogenase (quinone), and NAD(P)H:quinone oxidoreductase2 (misleading).

References[edit]