1-Aminomethyl-5-methoxyindane

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1-Aminomethyl-5-methoxyindane
1-aminomethyl-5-methoxyindane.svg
Clinical data
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
Formula C11H15NO
Molar mass 177.25 g·mol−1
3D model (JSmol)
 NYesY (what is this?)  (verify)

1-Aminomethyl-5-methoxyindane (AMMI), is a drug developed by a team led by David E. Nichols at Purdue University, which acts as a selective serotonin releasing agent (SSRA) and binds to the serotonin transporter with similar affinity to DFMDA.[1][2]

See also[edit]

References[edit]

  1. ^ Roman, D. L.; Saldaña, S. N.; Nichols, D. E.; Carroll, F. I.; Barker, E. L. (2004). "Distinct molecular recognition of psychostimulants by human and Drosophila serotonin transporters". Journal of Pharmacology and Experimental Therapeutics. 308 (2): 679–87. doi:10.1124/jpet.103.057836. PMID 14593087. 
  2. ^ Walline, C. C.; Nichols, D. E.; Carroll, F. I.; Barker, E. L. (2008). "Comparative molecular field analysis using selectivity fields reveals residues in the third transmembrane helix of the serotonin transporter associated with substrate and antagonist recognition". Journal of Pharmacology and Experimental Therapeutics. 325 (3): 791–800. doi:10.1124/jpet.108.136200. PMC 2637348Freely accessible. PMID 18354055.