1-hydroxy-2-naphthoate hydroxylase

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1-hydroxy-2-naphthoate hydroxylase
Identifiers
EC number 1.14.13.135
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

1-hydroxy-2-naphthoate hydroxylase (EC 1.14.13.135, 1-hydroxy-2-naphthoic acid hydroxylase) is an enzyme with systematic name 1-hydroxy-2-naphthoate,NAD(P)H:oxygen oxidoreductase (2-hydroxylating, decarboxylating).[1][2] This enzyme catalyses the following chemical reaction

1-hydroxy-2-naphthoate + NAD(P)H + H+ + O2 1,2-dihydroxynaphthalene + NAD(P)+ + H2O + CO2

1-hydroxy-2-naphthoate hydroxylase is involved in chrysene degradation in some bacteria.

References[edit]

  1. ^ Deveryshetty, J.; Phale, P.S. (2010). "Biodegradation of phenanthrene by Alcaligenes sp. strain PPH: partial purification and characterization of 1-hydroxy-2-naphthoic acid hydroxylase". FEMS Microbiol. Lett. 311 (1): 93–101. doi:10.1111/j.1574-6968.2010.02079.x. PMID 20727010. 
  2. ^ Nayak, A.S.; Sanjeev Kumar, S.; Santosh Kumar, M.; Anjaneya, O.; Karegoudar, T.B. (2011). "A catabolic pathway for the degradation of chrysene by Pseudoxanthomonas sp. PNK-04". FEMS Microbiol. Lett. 320 (2): 128–134. doi:10.1111/j.1574-6968.2011.02301.x. PMID 21545490. 

External links[edit]