Methylphenyltetrahydropyridine N-monooxygenase

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Methylphenyltetrahydropyridine N-monooxygenase
Identifiers
EC number 1.13.12.11
CAS number 37256-73-8
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Methylphenyltetrahydropyridine N-monooxygenase (EC 1.13.12.11) is an enzyme with systematic name 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine:oxygen N-oxidoreductase.[1] This enzyme catalyses the following chemical reaction

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine + O2 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine N-oxide + methanol

Methylphenyltetrahydropyridine N-monooxygenase is a flavoprotein.

References[edit]

  1. ^ Chiba, K.; Kubota, E.; Miyakawa, T.; Kato, Y.; Ishizaki, T. (1988). "Characterization of hepatic microsomal metabolism as an in vivo detoxication pathway of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice". J. Pharmacol. Exp. Ther. 246: 1108–1115. PMID 3262153. 

External links[edit]