12-hydroxydihydrochelirubine 12-O-methyltransferase

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12-hydroxydihydrochelirubine 12-O-methyltransferase
Identifiers
EC number 2.1.1.120
CAS number 158736-40-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a 12-hydroxydihydrochelirubine 12-O-methyltransferase (EC 2.1.1.120) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine S-adenosyl-L-homocysteine + dihydromacarpine

Thus, the two substrates of this enzyme are S-adenosyl methionine and 12-hydroxydihydrochelirubine, whereas its two products are S-adenosylhomocysteine and dihydromacarpine.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:12-hydroxydihydrochelirubine 12-O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.

References[edit]

  • Kammerer L, De-Eknamkul W, Zenk MH (1994). "Enzymic 12-hydroxylation and 12-O-methylation of dihydrochelirubine in dihydromacarpine formation by Thalictrum bulgaricum". Phytochemistry. 36 (6): 1409–1416. doi:10.1016/S0031-9422(00)89732-0.