15-Cis-phytoene desaturase

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15-cis-phytoene desaturase
Identifiers
EC number 1.3.5.5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

15-Cis-phytoene desaturase (EC 1.3.5.5, phytoene desaturase (ambiguous), PDS, plant-type phytoene desaturase) is an enzyme with systematic name 15-cis-phytoene:plastoquinone oxidoreductase.[1][2][3][4] This enzyme catalyses the following chemical reaction

15-cis-phytoene + 2 plastoquinone 9,15,9'-tricis-zeta-carotene + 2 plastoquinol (overall reaction)
(1a) 15-cis-phytoene + plastoquinone 15,9'-dicis-phytofluene + plastoquinol
(1b) 15,9'-dicis-phytofluene + plastoquinone 9,15,9'-tricis-zeta-carotene + plastoquinol

This enzyme is involved in carotenoid biosynthesis in plants and cyanobacteria.

References[edit]

  1. ^ Breitenbach, J.; Zhu, C.; Sandmann, G. (2001). "Bleaching herbicide norflurazon inhibits phytoene desaturase by competition with the cofactors". J. Agric. Food Chem. 49 (11): 5270–5272. doi:10.1021/jf0106751. PMID 11714315. 
  2. ^ Schneider, C.; Boger, P.; Sandmann, G. (1997). "Phytoene desaturase: heterologous expression in an active state, purification, and biochemical properties". Protein Expr. Purif. 10 (2): 175–179. doi:10.1006/prep.1997.0730. PMID 9226712. 
  3. ^ Fraser, P.D.; Linden, H.; Sandmann, G. (1993). "Purification and reactivation of recombinant Synechococcus phytoene desaturase from an overexpressing strain of Escherichia coli". Biochem. J. 291: 687–692. PMC 1132422Freely accessible. PMID 8489496. 
  4. ^ Breitenbach, J.; Sandmann, G. (2005). "ζ-Carotene cis isomers as products and substrates in the plant poly-cis carotenoid biosynthetic pathway to lycopene". Planta. 220: 785–793. doi:10.1007/s00425-004-1395-2. PMID 15503129. 

External links[edit]