1597 in science
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- Pieter Dirkszoon Keyser and Frederick de Houtman define 12 southern constellations (1595–1597), introduced later by Johann Bayer in the 1603 text Uranometria: Apus, Chamaeleon, Dorado, Grus, Hydrus, Indus, Musca, Pavo, Phoenix, Triangulum Australe, Tucana, Volans.
- April 13 – Giovanni Battista Hodierna, Italian astronomer (died 1660)
- Henry Gellibrand, English mathematician (died 1637)
- February 6 – Franciscus Patricius, Italian philosopher and scientist (born 1529)
- June 20 – Willem Barentsz, Dutch explorer (born c. 1550) (at sea)
- "From liquid to vapor and back: origins". Special Collections Department, University of Delaware Library. Retrieved 2007-03-12.