16-alpha-hydroxyprogesterone dehydratase

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16-alpha-hydroxyprogesterone dehydratase
Identifiers
EC number 4.2.1.98
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a 16alpha-hydroxyprogesterone dehydratase (EC 4.2.1.98) is an enzyme that catalyzes the chemical reaction

16alpha-hydroxyprogesterone 16,17-didehydroprogesterone + H2O

Hence, this enzyme has one substrate, 16alpha-hydroxyprogesterone, and two products, 16,17-didehydroprogesterone and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds, the systematic name of this enzyme class is 16alpha-hydroxyprogesterone hydro-lyase (16,17-didehydroprogesterone-forming). Other names in common use include hydroxyprogesterone dehydroxylase, 16alpha-hydroxyprogesterone dehydroxylase, 16alpha-dehydroxylase, and 16alpha-hydroxyprogesterone hydro-lyase.

References[edit]

  • Glass TL, Lamppa RS (1985). "Purification and properties of 16 alpha-hydroxyprogesterone dehydroxylase from Eubacterium sp. strain 144". Biochim. Biophys. Acta. 837 (2): 103–10. doi:10.1016/0005-2760(85)90232-2. PMID 4052439.