Come On Down is the debut EP by the Seattle-based alternative rock band Green River. It was released in October 1985 through Homestead Records, while the band were on their first US tour, it is considered the first grunge record because it was released several months before the Deep Six album, compiled by six other Seattle grunge bands. In the early 1980s, the Seattle branch of the indie movement was influenced by punk rock, however it removed its speed and its structure and added elements of metal. Although Malfunkshun and Soundgarden were more popular in Seattle at this time, Green River was the first band of this movement to release a recording. Come On Down has been described as a balance between punk and metal, being similar to a mashup of 1980s metal together with early Mudhoney, with the sound being "dirty". In audio engineering, the term "dirty" or "fuzzy" describes "the opposite of clean sound. A dirty tone would have some amount of noise, distortion, or overdrive in the signal."This record marks Green River's only record with original guitarist Steve Turner, other than the 2016 LP release of 1984 Demos, the 2019 LP release of Live At The Tropicana.

Turner left the group due to his dissatisfaction with bassist Jeff Ament and guitarist Stone Gossard's heavy metal leanings. The record was released to little fanfare, did not sell well. Allmusic describes the EP as "a worthwhile listen but not something that points towards the bright futures that its band members would enjoy." It contains the first recording of the song "Swallow My Pride", a song describing a lover's disdain for his girlfriend's feverish American patriotism, re-recorded for the band's debut album, Rehab Doll. In mid-1985, Green River embarked on its first nationwide tour to promote Come On Down. Release of the record was delayed however. From all accounts the experience was less than positive, though it did help cement alliances with other emerging American indie rock bands such as Sonic Youth. In 1986, the band continued to play in and around the Pacific Northwest to larger crowds. Leighton Beezer, who played with Mark Arm and Steve Turner in The Thrown Ups, states that when he first heard Green River play Come On Down, he realized that they were playing punk rock backwards.

Additionally, he noted that the augmented fifth note was used by Black Sabbath to produce an ominous feeling but it is not used in punk rock. In the 1996 grunge film documentary Hype!, Beezer demonstrated on guitar the difference between punk and grunge. First he played the riff from Rockaway Beach by The Ramones that ascends the neck of the guitar Come On Down by Green River that descends the neck; the two pieces are only a few notes apart but sound unalike. He took the same rhythm with the same chord, however descending the neck made it sound darker, therefore grunge. Your Own Best Friend is a bonus track on the 2018 remaster; the album’s title track discusses the Green River murders from the murderer’s point of view. Ridgway is the second most prolific serial killer in the U. S. All lyrics are written by Mark Arm. Green RiverJeff Ament – bass guitar and sleeve designs Mark Arm – vocals Stone Gossard – guitar Steve Turner – guitar Alex Vincent – drumsProductionGreen River – production, cover concept Chris Hanzsek – production, engineering Charles Peterson – photography, cover concept Paul Scoles – assistance Anderson, Kyle.

Accidental Revolution: The Story of Grunge. Macmillan. ISBN 978-0-312-35819-8

There are many proposed diseases and diagnoses that are rejected by orthodox medicine consensus and are associated with pseudoscience. Pseudoscientific diseases are not defined using objective criteria, they cannot achieve, do not seek, medical recognition. Physics Professor Roy Coker claims. Other conditions may be rejected or contested by orthodox medicine, but are not associated with pseudoscience. Diagnostic criteria for some of these conditions may be vague, over-inclusive, or otherwise ill-defined. Although the evidence for the disease may be contested or lacking, the justification for these diagnoses is empirical and therefore amenable to scientific investigation, at least in theory. Examples of conditions that are not pseudoscientific include: Conditions determined to be somatic in nature, including mass psychogenic illnesses. Medicalized conditions that are not pathogenic in nature, such as aging, pregnancy, sexual addiction, jet lag, halitosis. Conditions that are not recognized, about which there is an ongoing debate within the scientific and medical literature.

Functional disorders are a set of conditions that cannot be explained by structural or biochemical abnormalities. These raise challenges around diagnosis and treatment, with debate around whether they are psychogenic, they present with non-specific symptoms that are consistent with multiple causes. Examples include fibromyalgia, myalgic encephalomyelitis, Gulf War syndrome. Adrenal fatigue or hypoadrenia is a pseudoscientific diagnosis described as a state in which the adrenal glands are exhausted and unable to produce adequate quantities of hormones the glucocorticoid cortisol, due to chronic stress or infections. Adrenal fatigue should not be confused with a number of actual forms of adrenal dysfunction such as adrenal insufficiency or Addison's disease; the term "adrenal fatigue", invented in 1998 by James Wilson, a chiropractor, may be applied to a collection of nonspecific symptoms. There is no scientific evidence supporting the concept of adrenal fatigue and it is not recognized as a diagnosis by any scientific or medical community.

A systematic review found no evidence for the term adrenal fatigue, confirming the consensus among endocrinological societies that it is a myth. Autistic enterocolitis is a nonexistent medical condition proposed in 1998 by now-discredited British gastroenterologist Andrew Wakefield, who suggested a link between a number of common clinical symptoms and signs which he contended were distinctive to autism; the existence of such an enterocolitis has been dismissed by experts as having "not been established". Wakefield's fraudulent report, retracted in 2010, suppressed negative findings and used inadequate controls. Multiple attempts to replicate his results. Reviews in the medical literature have found no link between bowel disease. Candida hypersensitivity is the spuriously claimed chronic yeast infections responsible for many common disorders and non-specific symptoms, such as fatigue, weight gain, dizziness and joint pain, asthma; the notion has been disabused by the American Academy of Allergy and Immunology.

Chronic Lyme disease is a rejected diagnosis that encompasses "a broad array of illnesses or symptom complexes for which there is no reproducible or convincing scientific evidence of any relationship to Borrelia burgdorferi infection." This is different from Lyme Disease, not pseudoscientific. Despite numerous studies, there is no clinical evidence that "chronic" Lyme Disease is caused by a persistent infection, it is distinct from post-treatment Lyme disease syndrome, a set of lingering symptoms which may persist after successful treatment of infection with Lyme spirochetes. The symptoms of "chronic Lyme" are generic and non-specific "symptoms of life". Electromagnetic hypersensitivity is a reported sensitivity to electric and magnetic fields or electromagnetic radiation of various frequencies at exposure levels well below established safety standards. Symptoms are inconsistent, but can include headache, difficulty sleeping, as well as similar non-specific indications. Provocation studies find that the discomfort of sufferers is unrelated to hidden sources of radiation, "no scientific basis exists for a connection between EHS and exposure to."

Leaky gut syndrome is an alleged condition caused by the passage of harmful substances outward through the gut wall. Alternative medicine proponents claim it is the cause of many conditions including multiple sclerosis and autism, a claim, called pseudoscientific. According to the UK National Health Service, the theory is unproven; some skeptics and scientists say that the marketing of treatments for leaky gut syndrome is either misguided or an instance of deliberate health fraud. Morgellons is a self-diagnosed, unexplained skin condition in which individuals have sores that they believe contain some kind of fibers. Morgellons is poorly characterized but the general medical consensus is that it is a form of delusional parasitosis. An attempt to link Morgellons to the cause of Lyme disease has been attacked by Steven Salzberg as "dangerous pseudoscience". Multiple chemical sensitivity Reward deficiency syndrome "Vaccine overload", a non-medical term for the notion that giving many vaccines at once may overwhelm or weaken a child's immature immune system and lead to adverse effects, is contradicted by scientific evidence.

Vertebral subluxation is a chiropractic diagnosis that involves a site of impaired flow of innate or a spinal lesion, postulated to cause neuromusculoske