16S rRNA (guanine966-N2)-methyltransferase

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16S rRNA (guanine966-N2)-methyltransferase
Identifiers
EC number 2.1.1.171
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

16S rRNA (guanine966-N2)-methyltransferase (EC 2.1.1.171, yhhF (gene), rsmD (gene), m2G966 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (guanine966-N2)-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + guanine966 in 16S rRNA S-adenosyl-L-homocysteine + N2-methylguanine966 in 16S rRNA

The enzyme efficiently methylates guanine966 of the assembled 30S subunits in vitro.

References[edit]

  1. ^ Lesnyak, D.V.; Osipiuk, J.; Skarina, T.; Sergiev, P.V.; Bogdanov, A.A.; Edwards, A.; Savchenko, A.; Joachimiak, A.; Dontsova, O.A. (2007). "Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure". J. Biol. Chem. 282 (8): 5880–5887. doi:10.1074/jbc.m608214200. PMC 2885967Freely accessible. PMID 17189261. 

External links[edit]