19-Noretiocholanolone

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19-Noretiocholanolone
19-Noretiocholanolone.svg
Clinical data
Synonyms Noretiocholanolone; 5β-Estran-3α-ol-17-one; 3α-Hydroxy-5β-estran-17-one
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
Formula C18H28O2
Molar mass 276.42 g·mol−1
3D model (JSmol)

19-Noretiocholanolone, also known as 5β-estran-3α-ol-17-one, is a metabolite of nandrolone (19-nortestosterone) and bolandione (19-norandrostenedione) that is formed by 5α-reductase. It is on the list of substances prohibited by the World Anti-Doping Agency since it is a detectable metabolite of nandrolone, an anabolic-androgenic steroid (AAS).[1]

Traces of 19-noretiocholanolone may be naturally present in human urine.[citation needed] Consumption of boar meat, liver, kidneys and heart have been found to increase urinary 19-noretiocholanolone output.[2]

See also[edit]

References[edit]

  1. ^ "THE 2007 PROHIBITED LIST INTERNATIONAL STANDARD" (PDF). The World Anti-Doping Code. World Anti-Doping Agency. Archived from the original (PDF) on 10 April 2009. Retrieved 2009-05-14. 
  2. ^ Le Bizec B, Gaudin I, Monteau F, Andre F, Impens S, De Wasch K, De Brabander H (2000). "Consequence of boar edible tissue consumption on urinary profiles of nandrolone metabolites. I. Mass spectrometric detection and quantification of 19-norandrosterone and 19-noretiocholanolone in human urine". Rapid Commun. Mass Spectrom. 14 (12): 1058–65. doi:10.1002/1097-0231(20000630)14:12<1058::AID-RCM991>3.0.CO;2-7. PMID 10861987.