The 1953 Giro d'Italia was the 36th edition of the Giro d'Italia. The Giro started off in Milan on 12 May with a 263 km (163.4 mi) flat stage and concluded back in Milan with a 220 km (136.7 mi) relatively flat mass-start stage on 2 June. Sixteen teams entered the race, which was won by Italian Fausto Coppi of the Bianchi team. Second and third respectively were Swiss rider Hugo Koblet and Italian Pasquale Fornara.

Angelo Fausto Coppi was an Italian cyclist, the dominant international cyclist of the years after the Second World War. His successes earned him the title Il Campionissimo. He was an all-round racing cyclist: he excelled in both climbing and time trialing, and was also a good sprinter. He won the Giro d'Italia five times, the Tour de France twice, and the World Championship in 1953. Other notable results include winning the Giro di Lombardia five times, the Milan–San Remo three times, as well as wins at Paris–Roubaix and La Flèche Wallonne and setting the hour record (45.798 km) in 1942.