The 2010 Giro d'Italia was the 93rd edition of the Giro d'Italia, one of cycling's Grand Tours. The race started off in Amsterdam on 8 May and stayed in the Netherlands for three stages, before leaving the country. The route included climbs such as Monte Zoncolan, Plan de Corones, the Passo del Mortirolo and the Passo di Gavia before ending in Verona with an individual time trial.

The Giro d'Italia is an annual multiple-stage bicycle race primarily held in Italy, while also starting in, or passing through, other countries. The first race was organized in 1909 to increase sales of the newspaper La Gazzetta dello Sport, and the race is still run by a subsidiary of that paper's owner. The race has been held annually since its first edition in 1909, except during the two world wars. As the Giro gained prominence and popularity the race was lengthened, and the peloton expanded from primarily Italian participation to riders from all over the world. The Giro is a UCI World Tour event, which means that the teams that compete in the race are mostly UCI WorldTeams, with some additional teams invited as 'wild cards'.