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Democratic Voice of Burma

The Democratic Voice of Burma started as a non-profit media organization based in Oslo and Chiang Mai, Thailand. Run by Burmese expatriates, it made radio and television broadcasts aimed at providing uncensored news and information about Burma. Since 2012 DVB moved back into Burma, where it is now an independent media company, called'DVB Multimedia Group'. In July 1992, DVB began broadcasting programming into Burma from studios in Oslo and transmitting via shortwave radio from the Norwegian transmitter at Kvitsoy. Now the broadcast is sent via free-to-air digital tv. On May 28, 2005, DVB expanded its programming and began satellite television broadcasts into the country; the organization stated that it hoped to reach some ten million Burmese through this new effort, funded in part by non-governmental organizations such as Free Voice of the Netherlands, the National Endowment for Democracy, the Freedom of Expression Foundation. In 2012, DVB started multimedia operations inside Myanmar running a branch office with its former underground VJs.

In March 24, 2018, DVB started broadcasting on digital terrestrial television on MRTV DVB-T2 multiplex system. DVB states that it has four primary goals: the provision of "accurate and unbiased news to the people of Burma" to "promote understanding and cooperation" among Burma's religious and ethnic populations to "encourage and sustain independent public opinion" and to provide for "social and political debate" to "impart the ideals of democracy and human rights" to the Burmese people 2007 Burmese anti-government protests National Coalition Government of the Union of Burma Burma VJ Official website NBC News report Dawna Friesen, "Myanmar regime trying to suppress protestors", September 26, 2007 Burmese officer wants asylum in Norway, Live streaming on Livestation Eyes of the Storm PBS documentary shot by Democratic Voice of Burma

Seaborne target

Seaborne targets are vessels or floating structures that are shot at for practice by naval or air forces. They may be remotely controlled and mobile, or towed behind other craft, or just set adrift in the sea. Target ships are vessels obsolete or captured warships, used for naval gunnery practice or for weapons testing – most spectacularly in Operation Crossroads, where 95 ships were sunk in a U. S. nuclear weapons test at Bikini Atoll. In the U. S. Navy, a Seaborne Powered Target is an unmanned surface vehicle used as the naval counterpart of a target drone, they are remote-controlled, all but the smallest can be equipped with electromagnetic emitters to appear as a larger ship on sensors. As of 2013, U. S. Navy SEPTARs include: Hammerhead usv-t: A high-speed drone capable of multiple vessel attacks. Mobile Ship Target: A ship-sized target some 260 feet long, with a top speed of 15 knots. QST-35: A fiberglass boat with a top speed of 30 knots, usable manned or unmanned, or as a mine countermeasure.

Fast-Attack Craft Target: A smaller, more agile fiberglass boat with a top speed of 50 knots, intended to challenge gunners. High-Speed Maneuvering Surface Target: A boat similar to a harbor patrol boat, designed for operations in shallow waters, with a top speed of 46 knots. Ship-Deployable Surface Target: A small craft similar to a water scooter, which can be used as one, with a top speed of 49 knots. Targets can be towed behind other craft, the counterparts of target tugs in aviation; the U. S. Navy employs the Low-Cost Modular Target, a modular barge made from pontoons and large colored sails as visual targets, which can be shot at with guns or a variety of missiles, it is towed by a HSMST. Navies have used all sort such as empty barrels. Modern free-floating targets are large and bright orange.

Coefficient matrix

In linear algebra, a coefficient matrix is a matrix consisting of the coefficients of the variables in a set of linear equations. The matrix is used in solving systems of linear equations. In general, a system with m linear equations and n unknowns can be written as a 11 x 1 + a 12 x 2 + ⋯ + a 1 n x n = b 1 a 21 x 1 + a 22 x 2 + ⋯ + a 2 n x n = b 2 ⋮ a m 1 x 1 + a m 2 x 2 + ⋯ + a m n x n = b m where x 1, x 2... X n are the unknowns and the numbers a 11, a 12... a m n are the coefficients of the system. The coefficient matrix is the mxn matrix with the coefficient a i j as the -th entry: Then the above set of equations can be expressed more succinctly as A x = b where A is the coefficient matrix and b is the column vector of constant terms. By the Rouché–Capelli theorem, the system of equations is inconsistent, meaning it has no solutions, if the rank of the augmented matrix is greater than the rank of the coefficient matrix. If, on the other hand, the ranks of these two matrices are equal, the system must have at least one solution.

The solution is only if the rank r equals the number n of variables. Otherwise the general solution has n – r free parameters. A first-order matrix difference equation with constant term can be written as y t + 1 = A y t + c, where A is n × n and y and c are n × 1; this system converges to its steady-state level of y if and only if the absolute values of all n eigenvalues of A are less than 1. A first-order matrix differential equation with constant term can be written; this system is stable if and only if all n eigenvalues of A have negative real parts

LOC105377021

LOC105377021 is a protein which in humans is encoded by the LOC105377021 gene. LOC105377021 exhibits expressional pathology related to breast cancer triple negative breast cancer. LOC105377021 contains a serine rich region in addition to predicted alpha helix motifs. LOC105377021 localizes to Homo sapiens chromosome 3, approximate to the reading frame of TRIM71; the corresponding gene has 2,473 nucleotides. There is one exon in the LOC105377021p mRNA. There is no predicted alternative splicing on the NCBI gene database; the figure below shows the basic primary protein structure, with N-terminus and C-terminus in their respective annotations. The orange domain is a predicted nuclear localization sequence, while the blue domain is the remainder of the LOC105377021 exon. According to Ali2D, LOC105377021 is predicted to form alpha helix. LOC105377021 has a prominent, C-terminus repeat of serine residues for disulfide bonding. One disulfide bond was predicted by DISULFIDE software. Additionally, the I TASSER profile shows several alpha helices in a variety of different colors, in addition to potential turn motifs.

A predicted protein modification of LOC105377021 is phosphorylation, with sites throughout the protein, including the serine rich construct near the C-terminus of the protein. In addition, there is predicted evidence of O-Linked β-N-acetylglucosamine supplements in the C terminal region. There is predicted evidence for a nuclear localization sequence oriented at the N-terminal, provided by PSORT with partial support by PHOBIUS software. Compared to the average expression of human protein, LOC105377021 is expressed at 0.9%, classified as low. In humans: cranial, ovarian and testicular tissues corroborate this trend. Microarray data posits the expression of LOC105377021 in certain breast cancer tissues, including metastases to lymphatic and lung tissue. There is potential evidence for higher expression of LOC105377021 during Triple Negative Breast Cancer, which overshadows normal secretion levels for said protein; the figure below shows a potential trend line for this pattern. As the figure legend states, the red bars refer to the left axis for sample counts, whereas the blue dots show the percentage of LOC105377021 expression within each sample.

This photo is courtesy of NCBI Geo Profiles Accession GDS4069. Seven key brain tissues express LOC105377021 according to an Allen Brain Atlas probe; the temporal lobe, parietal lobe, cingulate gyrus, parahippocampal gyrus, insula are five overarching regions of the seven brain tissues where expression was highlighted. The annotated figures below serve as holistic representations of cranial expression in the context of LOC105377021. Light blue shaded regions posit more dense expression of LOC105377021, where as darker green and brighter red show less and least amounts of expression respectively. All seven expression areas, including the middle temporal gyrus, the short insular gyrus, the postcentral gyrus, the cingulate gyrus, the inferior temporal gyrus, the parahippocampal gyrus, the superior temporal gyrus are depicted in Allen Brain Atlas profiles below; these photos are courtesy of the Allen Brain Atlas. The Basic Local Alignment Sequence Tool shows that LOC105377021 orthologs are homogenous and mammalian.

Important orthologs are summarized into three categories: primates, aquatic mammals, ferrets/ferret-like animals. Pongo abelii and Tursiops truncatus are related orthologs respectively; the river dolphin is the first ortholog to detach from the 80% plus similarity cohort. The following includes a list of select orthologs found: The pace of evolution of LOC105377021 upon its inception is modeled to be slow; this speed is relative to cytochrome c 6A1 and Alpha fibrinogen using corrected divergence methods. The corrected divergences graph above shows three lines: Alpha Fibrinogen in Red, LOC Ortholog in blue, Cytochrome c 6A1 in green; these lines associate with evolutionary pace in LOC105377021, as tested using a corrected divergence genomic analysis. The following diagram shows single nucleotide polymorphisms in various regions of the protein. SNP's are highlighted green, with SNP coding on the right hand coding for switches in amino acids. According to Genomatix, LOC389102 is proximate to a 601 base pair promoter and a 5'UTR 129 base pairs long consecutively.

Genomatix predicts several transcription factors in general. Two select factors predicted include Gli3 and E2F1

Well-woman examination

A well woman examination is an exam offered to women to review elements of their reproductive health. It is recommended once a year for most women; the exam includes a breast examination, a pelvic examination and a pap smear but may include other procedures. Hospitals employ strict policies relating to the provision of consent by the patient, the availability of chaperones at the examination, the absence of other parties; the well-woman examination by a medical professional is recommended at least once a year to women over 18 years old and/or women who are sexually active. Its importance lies in identifying potential early health problems; the most important tests included in an examination is the breast exam, pelvic exam and the pap test, although some doctors consider other tests in the examination, including measurement of blood pressure, HIV testing, other laboratory tests such as urinalysis, CBC and testing for other sexually transmitted diseases. The procedure is important to detect certain cancers breast and cervical cancer.

The breast examination begins with a visual inspection. With the patient in a supine or seated position, the medical professional will look at both breasts to check the color, dimensions according to age, lean body mass, the physiological and race, looking for abnormalities, such as bulges and shrinkage. One of these abnormalities is changed in the nipple. If it is flattened or retracted, it is necessary to consider the possibility of a cancerous lesion which has caused the malformation. Next, the breasts are palpated, again with the patient sitting; the patient has to put one hand behind her head. With this position, the entire gland is palpated, it is important to examine the armpits, because of masses that may be found there. The test is executed pressing the gland with two or three fingers against the chest wall, making a radial route or by quadrants; the nipple is squeezed check for secretions, such as secretion of milk, blood or purulent secretions. If a node is detected, it is necessary to determine its place, shape, edges and sensitivity.

In addition to the yearly check by a professional, women over the age of 18 should perform this examination monthly. It is important because regular and comprehensive examinations of the breasts can be used to find breast changes that occur between every clinical examination and detect early breast cancer; this auto examination should to be performed seven days after the onset of the menstrual period. If a woman finds a lump or notice any changes in her breast, she should seek medical attention promptly. A mammogram or mammography is a special x-ray of the breasts, they are the procedure most to detect early breast cancer in asymptomatic women. Mammograms can show tumors long, they are recommended for women who have symptoms of breast cancer or who are at increased risk of developing the disease. They are performed with the patient standing, the breast pressed between two plastic plates, as the image is taken; the interpretation has to be performed by a specialist. Breast ultrasound is a complementary study of mammography.

In many women the tissue that makes up the breast is dense, representing fibrous tissue and glandular tissue, which produces milk during lactation. This limits the radiologist interpreting the study, so, in these cases, the ultrasound is helpful, since this is capable of distinguishing tumors in women with dense breast tissue, where identification is otherwise difficult. Additionally, it is advisable to follow up a mammogram that shows indications of tumors with an ultrasound, to confirm, before more invasive procedures are undertaken; the pelvic exam is part of the physical examination of the pelvic area of a woman, which also includes the taking of a sample for a pap smear. This test includes three parts; these are the general inspection of the external genitalia, bimanual examination, inspection of the vaginal canal using a speculum. The patient is placed in a supine position on a special examination table, which has two protrusions called "stirrups." With the feet in these stirrups, the legs are placed in a position such that the medical professional can access the pelvic area.

The external genitalia is examined first, looking for abnormalities like lesions, ulcers and color changes. The elements of this exam include the vulva, which contains the mons pubis, of which there are two longitudinal folds of skin forming the labia majora; the clitoral hood is checked. The purpose of this exam is to palpate organs; the index and middle finger are inserted into the vagina. This maneuver allows the doctor to check the orientation and width of the vagina. Next, the cervix and vaginal fornices are palpated, to check position, consistency and sensibility; the other hand is placed in the pubis pressing it to feel the uterus between both hands. The most important characteristics to examine are the size of the uterus, presence of nodes or agglomerations, size and mobility. With this technique, the ovaries are palpable; the speculum examination is recommended for only women over 21 years old, irrespective of her sexual activity. The speculum is an instrument is constructed with two flaps.

Its purpose is to keep it open. This allows direct observation by the physician into the vaginal canal with the help of a lamp or a mirror. There are different types of speculums used within the different characteristics of each patient such as age, sex li