Anatomical terms of location
Standard anatomical terms of location deal unambiguously with the anatomy of animals, including humans. All vertebrates have the same basic body plan – they are bilaterally symmetrical in early embryonic stages and bilaterally symmetrical in adulthood; that is, they have mirror-image left and right halves if divided down the middle. For these reasons, the basic directional terms can be considered to be those used in vertebrates. By extension, the same terms are used for many other organisms as well. While these terms are standardized within specific fields of biology, there are unavoidable, sometimes dramatic, differences between some disciplines. For example, differences in terminology remain a problem that, to some extent, still separates the terminology of human anatomy from that used in the study of various other zoological categories. Standardized anatomical and zoological terms of location have been developed based on Latin and Greek words, to enable all biological and medical scientists to delineate and communicate information about animal bodies and their component organs though the meaning of some of the terms is context-sensitive.
The vertebrates and Craniata share a substantial heritage and common structure, so many of the same terms are used for location. To avoid ambiguities this terminology is based on the anatomy of each animal in a standard way. For humans, one type of vertebrate, anatomical terms may differ from other forms of vertebrates. For one reason, this is because humans have a different neuraxis and, unlike animals that rest on four limbs, humans are considered when describing anatomy as being in the standard anatomical position, thus what is on "top" of a human is the head, whereas the "top" of a dog may be its back, the "top" of a flounder could refer to either its left or its right side. For invertebrates, standard application of locational terminology becomes difficult or debatable at best when the differences in morphology are so radical that common concepts are not homologous and do not refer to common concepts. For example, many species are not bilaterally symmetrical. In these species, terminology depends on their type of symmetry.
Because animals can change orientation with respect to their environment, because appendages like limbs and tentacles can change position with respect to the main body, positional descriptive terms need to refer to the animal as in its standard anatomical position. All descriptions are with respect to the organism in its standard anatomical position when the organism in question has appendages in another position; this helps avoid confusion in terminology. In humans, this refers to the body in a standing position with arms at the side and palms facing forward. While the universal vertebrate terminology used in veterinary medicine would work in human medicine, the human terms are thought to be too well established to be worth changing. Many anatomical terms can be combined, either to indicate a position in two axes or to indicate the direction of a movement relative to the body. For example, "anterolateral" indicates a position, both anterior and lateral to the body axis. In radiology, an X-ray image may be said to be "anteroposterior", indicating that the beam of X-rays pass from their source to patient's anterior body wall through the body to exit through posterior body wall.
There is no definite limit to the contexts in which terms may be modified to qualify each other in such combinations. The modifier term is truncated and an "o" or an "i" is added in prefixing it to the qualified term. For example, a view of an animal from an aspect at once dorsal and lateral might be called a "dorsolateral" view. Again, in describing the morphology of an organ or habitus of an animal such as many of the Platyhelminthes, one might speak of it as "dorsiventrally" flattened as opposed to bilaterally flattened animals such as ocean sunfish. Where desirable three or more terms may be agglutinated or concatenated, as in "anteriodorsolateral"; such terms sometimes used to be hyphenated. There is however little basis for any strict rule to interfere with choice of convenience in such usage. Three basic reference planes are used to describe location; the sagittal plane is a plane parallel to the sagittal suture. All other sagittal planes are parallel to it, it is known as a "longitudinal plane".
The plane is perpendicular to the ground. The median plane or midsagittal plane is in the midline of the body, divides the body into left and right portions; this passes through the head, spinal cord, and, in many animals, the tail. The term "median plane" can refer to the midsagittal plane of other structures, such as a digit; the frontal plane or coronal plane divides the body into ventral portions. For post-embryonic humans a coronal plane is vertical and a transverse plane is horizontal, but for embryos and quadrupeds a coronal plane is horizontal and a transverse plane is vertical. A longitudinal plane is any plane perpendicular to the transverse plane; the coronal plane and the sagittal plane are examples of longitudinal planes. A transverse plane known as a cross-section, divides the body into cranial and caudal portions. In human anatomy: A transverse plane is an X-Z plane, parallel to the ground, which s
Interphalangeal joints of the hand
The interphalangeal joints of the hand are the hinge joints between the phalanges of the fingers that provide flexion towards the palm of the hand. There are two sets in each finger: "proximal interphalangeal joints", those between the first and second phalanges "distal interphalangeal joints", those between the second and third phalangesAnatomically, the proximal and distal interphalangeal joints are similar. There are some minor differences in how the palmar plates are attached proximally and in the segmentation of the flexor tendon sheath, but the major differences are the smaller dimension and reduced mobility of the distal joint; the PIP joint exhibits great lateral stability. Its transverse diameter is greater than its antero-posterior diameter and its thick collateral ligaments are tight in all positions during flexion, contrary to those in the metacarpophalangeal joint; the capsule, extensor tendon, skin are thin and lax dorsally, allowing for both phalanx bones to flex more than 100° until the base of the middle phalanx makes contact with the condylar notch of the proximal phalanx.
At the level of the PIP joint the extensor mechanism splits into three bands. The central slip attaches to the dorsal tubercle of the middle phalanx near the PIP joint; the pair of lateral bands, to which contribute the extensor tendons, continue past the PIP joint dorsally to the joint axis. These three bands are united by a transverse retinacular ligament, which runs from the palmar border of the lateral band to the flexor sheath at the level of the joint and which prevents dorsal displacement of that lateral band. On the palmar side of the joint axis of motion, lies the oblique retinacular ligament which stretches from the flexor sheath over the proximal phalanx to the terminal extensor tendon. In extension, the oblique ligament prevents passive DIP flexion and PIP hyperextension as it tightens and pulls the terminal extensor tendon proximally. In contrast, on the palmar side, a thick ligament prevents hyperextension; the distal part of the palmar ligament, called the palmar plate, is 2 to 3 millimetres thick and has a fibrocartilaginous structure.
The presence of chondroitin and keratan sulfate in the dorsal and palmar plates is important in resisting compression forces against the condyles of the proximal phalanx. Together these structures protect the tendons passing behind the joint; these tendons can sustain traction forces thanks to their collagen fibers. The palmar ligament is more flexible in its central-proximal part. On both sides it is reinforced by the so-called check rein ligaments; the accessory collateral ligaments originate at the proximal phalanx and are inserted distally at the base of the middle phalanx below the collateral ligaments. The accessory ligament and the proximal margin of the palmar plate are flexible and fold back upon themselves during flexion; the flexor tendon sheaths are attached to the proximal and middle phalanges by annular pulleys A2 and A4, while the A3 pulley and the proximal fibres of the C1 ligament attach the sheaths to the mobile volar ligament at the PIP joint. During flexion this arrangement produces a space at the neck of the proximal phalanx, filled by the folding palmar plate.
The palmar plate is supported by a ligament on either side of the joint called the collateral ligaments, which prevent deviation of the joint from side to side. The ligaments can or tear and can avulse with a small fracture fragment when the finger is forced backwards into hyperextension; this is called a "palmar plate, or volar plate injury". The palmar plate forms a semi-rigid floor and the collateral ligaments the walls in a mobile box which moves together with the distal part of the joint and provides stability to the joint during its entire range of motion; because the palmar plate adheres to the flexor digitorum superficialis near the distal attachment of the muscle, it increases the moment of flexor action. In the PIP joint, extension is more limited because of the two so called check-rein ligaments, which attach the palmar plate to the proximal phalanx; the only movements permitted in the interphalangeal joints are extension. Flexion is more extensive, about 100°, in the PIP joints and more restricted, about 80°, in the DIP joints.
Extension is limited by the collateral ligaments. The muscles generating these movements are: The relative length of the digit varies during motion of the IP joints; the length of the palmar aspect decreases during flexion while the dorsal aspect increases by about 24 mm. The useful range of motion of the PIP joint is 30–70°, increasing from the index finger to the little finger. During maximum flexion the base of the middle phalanx is pressed into the retrocondylar recess of the proximal phalanx, which provides maximum stability to the joint; the stability of the PIP joint is dependent of the tendons passing around it. Rheumatoid arthritis spares the distal interphalangeal joints. Therefore, arthritis of the distal interphalangeal joints suggests the presence of osteoarthritis or psoriatic arthritis. Interphalangeal joints of foot Hand kinesiology at the University of Kansas Medical Center Diagram at depuy.com Volar Plate Injury - Hand Therapy This article incorporates text in the public domain from page 333 of the 20th edition of Gray's Anatomy
A primordium in embryology, is an organ or tissue in its earliest recognizable stage of development. Cells of the primordium are called primordial cells. A primordium is the simplest set of cells capable of triggering growth of the would-be organ and the initial foundation from which an organ is able to grow. In flowering plants, a floral primordium gives rise to a flower. Although it is a used term in plant biology, the word is used in describing the biology of all multicellular organisms Plants produce both leaf and flower primordia cells at the shoot apical meristem. Primordium development in plants is critical to the proper positioning and development of plant organs and cells; the process of primordium development is intricately regulated by a set of genes that affect the positioning and differentiation of the primordium. Genes including STM and CUC are involved in defining the borders of the newly formed primordium; the plant hormone auxin has been implicated in this process, with the new primordium being initiated at the placenta, where the auxin concentration is highest.
There is still much to understand about the genes involved in primordium development. Leaf primordia are groups of cells; these new leaves resemble knobby outgrowths or inverted cones. Flower primordia are the little buds. Flower primordia start off as a crease or indentation and form into a bulge; this bulging is caused by less anisotropic, or directionally dependent, growth. Anlage Morphogenesis Primordial phallus List of biological development disorders
Anatomical terms of muscle
Muscles are described using unique anatomical terminology according to their actions and structure. There are three types of muscle tissue in the human body: skeletal and cardiac. Skeletal striated muscle, or "voluntary muscle" joins to bone with tendons. Skeletal muscle maintains posture. Smooth muscle tissue is found in parts of the body; the majority of this type of muscle tissue is found in the digestive and urinary systems where it acts by propelling forward food and feces in the former and urine in the latter. Other places smooth muscle can be found are within the uterus, where it helps facilitate birth, the eye, where the pupillary sphincter controls pupil size. Cardiac muscle is specific to the heart, it is involuntary in its movement, is additionally self-excitatory, contracting without outside stimuli. As well as anatomical terms of motion, which describe the motion made by a muscle, unique terminology is used to describe the action of a set of muscles. Agonist muscles and antagonist muscles refer to muscles that inhibit a movement.
Agonist muscles cause a movement to occur through their own activation. For example, the triceps brachii contracts, producing a shortening contraction, during the up phase of a push-up. During the down phase of a push-up, the same triceps brachii controls elbow flexion while producing a lengthening contraction, it is still the agonist, because while resisting gravity during relaxing, the triceps brachii continues to be the prime mover, or controller, of the joint action. Agonists are interchangeably referred to as "prime movers," since they are the muscles considered responsible for generating or controlling a specific movement. Another example is the dumbbell curl at the elbow; the "elbow flexor" group is the agonist. During the lowering phase the "elbow flexor" muscles lengthen, remaining the agonists because they are controlling the load and the movement. For both the lifting and lowering phase, the "elbow extensor" muscles are the antagonists, they shorten during the dumbbell lowering phase.
Here it is important to understand that it is common practice to give a name to a muscle group based on the joint action they produce during a shortening contraction. However, this naming convention does not mean; this term describes the function of skeletal muscles. Antagonist muscles are the muscles that produce an opposing joint torque to the agonist muscles; this torque can aid in controlling a motion. The opposing torque can slow movement down - in the case of a ballistic movement. For example, during a rapid discrete movement of the elbow, such as throwing a dart, the triceps muscles will be activated briefly and to accelerate the extension movement at the elbow, followed immediately by a "burst" of activation to the elbow flexor muscles that decelerates the elbow movement to arrive at a quick stop. To use an automotive analogy, this would be similar to pressing your gas pedal and immediately pressing the brake. Antagonism is not an intrinsic property of a particular muscle group. During slower joint actions that involve gravity, just as with the agonist muscle, the antagonist muscle can shorten and lengthen.
Using the example above of the triceps brachii during a push-up, the elbow flexor muscles are the antagonists at the elbow during both the up phase and down phase of the movement. During the dumbbell curl, the elbow extensors are the antagonists for both the lifting and lowering phases. Antagonist and agonist muscles occur in pairs, called antagonistic pairs; as one muscle contracts, the other relaxes. An example of an antagonistic pair is the triceps. "Reverse motions" need antagonistic pairs located in opposite sides of a joint or bone, including abductor-adductor pairs and flexor-extensor pairs. These consist of an extensor muscle, which "opens" the joint and a flexor muscle, which does the opposite by decreasing the angle between two bones. However, muscles don't always work this way. Sometimes during a joint action controlled by an agonist muscle, the antagonist will be activated, naturally; this occurs and is not considered to be a problem unless it is excessive or uncontrolled and disturbs the control of the joint action.
This serves to mechanically stiffen the joint. Not all muscles are paired in this way. An example of an exception is the deltoid. Synergist muscles help perform, the same set of joint motion as the agonists. Synergists muscles act on movable joints. Synergists are sometimes referred to as "neutralizers" because they help cancel out, or neutralize, extra motion from the agonists to make sure that the force generated works within the desired plane of motion. Muscle fibers can only contract up to 40% of their stretched length, thus the short fibers of pennate muscles are more suitable where power rather than range of contraction is required. This limitation in the range of contraction affects all muscles, those that act over several joints may be unable to shorten sufficiently to produce
The pisohamate ligament is a ligament in the hand. It is the volar ligament, it is a prolongation of the tendon of the flexor carpi ulnaris. It serves as part of the origin for the abductor digiti minimi, it forms the roof of the ulnar canal, a cannal that allows the ulnar nerve and ulnar artery into the hand. This article incorporates text in the public domain from page 329 of the 20th edition of Gray's Anatomy
Skin is the soft outer tissue covering of vertebrates with three main functions: protection and sensation. Other animal coverings, such as the arthropod exoskeleton, have different developmental origin and chemical composition; the adjective cutaneous means "of the skin". In mammals, the skin is an organ of the integumentary system made up of multiple layers of ectodermal tissue, guards the underlying muscles, bones and internal organs. Skin of a different nature exists in amphibians and birds. All mammals have some hair on their skin marine mammals like whales and porpoises which appear to be hairless; the skin is the first line of defense from external factors. For example, the skin plays a key role in protecting the body against pathogens and excessive water loss, its other functions are insulation, temperature regulation and the production of vitamin D folates. Damaged skin may heal by forming scar tissue; this is sometimes depigmented. The thickness of skin varies from location to location on an organism.
In humans for example, the skin located under the eyes and around the eyelids is the thinnest skin in the body at 0.5 mm thick, is one of the first areas to show signs of aging such as "crows feet" and wrinkles. The skin on the palms and the soles of the feet is the thickest skin on the body; the speed and quality of wound healing in skin is promoted by the reception of estrogen. Fur is dense hair. Fur augments the insulation the skin provides but can serve as a secondary sexual characteristic or as camouflage. On some animals, the skin is hard and thick, can be processed to create leather. Reptiles and fish have hard protective scales on their skin for protection, birds have hard feathers, all made of tough β-keratins. Amphibian skin is not a strong barrier regarding the passage of chemicals via skin and is subject to osmosis and diffusive forces. For example, a frog sitting in an anesthetic solution would be sedated as the chemical diffuses through its skin. Amphibian skin plays key roles in everyday survival and their ability to exploit a wide range of habitats and ecological conditions.
Mammalian skin is composed of two primary layers: the epidermis, which provides waterproofing and serves as a barrier to infection. It forms a protective barrier over the body's surface, responsible for keeping water in the body and preventing pathogens from entering, is a stratified squamous epithelium, composed of proliferating basal and differentiated suprabasal keratinocytes. Keratinocytes are the major cells, constituting 95% of the epidermis, while Merkel cells and Langerhans cells are present; the epidermis can be further subdivided into the following strata or layers: Stratum corneum Stratum lucidum Stratum granulosum Stratum spinosum Stratum germinativum Keratinocytes in the stratum basale proliferate through mitosis and the daughter cells move up the strata changing shape and composition as they undergo multiple stages of cell differentiation to become anucleated. During that process, keratinocytes will become organized, forming cellular junctions between each other and secreting keratin proteins and lipids which contribute to the formation of an extracellular matrix and provide mechanical strength to the skin.
Keratinocytes from the stratum corneum are shed from the surface. The epidermis contains no blood vessels, cells in the deepest layers are nourished by diffusion from blood capillaries extending to the upper layers of the dermis; the epidermis and dermis are separated by a thin sheet of fibers called the basement membrane, made through the action of both tissues. The basement membrane controls the traffic of the cells and molecules between the dermis and epidermis but serves, through the binding of a variety of cytokines and growth factors, as a reservoir for their controlled release during physiological remodeling or repair processes; the dermis is the layer of skin beneath the epidermis that consists of connective tissue and cushions the body from stress and strain. The dermis provides tensile strength and elasticity to the skin through an extracellular matrix composed of collagen fibrils and elastic fibers, embedded in hyaluronan and proteoglycans. Skin proteoglycans are varied and have specific locations.
For example, hyaluronan and decorin are present throughout the dermis and epidermis extracellular matrix, whereas biglycan and perlecan are only found in the epidermis. It harbors many mechanoreceptors that provide the sense of touch and heat through nociceptors and thermoreceptors, it contains the hair follicles, sweat glands, sebaceous glands, apocrine glands, lymphatic vessels and blood vessels. The blood vessels in the dermis provide nourishment and waste removal from its own cells as well as for the epidermis; the dermis is connected to the epidermis through a basement membrane and is structurally divided into two areas: a superficial area adjacent to the epidermis, called the papillary region, a deep thicker area known as the reticular region. The papillary region is composed of loose areolar connective tissue; this is named for its fingerlike projections called papillae. The papillae provide the dermis with a "bumpy" surface that interdigitates with the epidermis, strengthening the connection between the tw
Fat is one of the three main macronutrients, along with carbohydrate and protein. Fats molecules consist of carbon and hydrogen atoms, thus they are all hydrocarbon molecules. Examples include cholesterol and triglycerides; the terms "lipid", "oil" and "fat" are confused. "Lipid" is the general term, though a lipid is not a triglyceride. "Oil" refers to a lipid with short or unsaturated fatty acid chains, liquid at room temperature, while "fat" refers to lipids that are solids at room temperature – however, "fat" may be used in food science as a synonym for lipid. Fats, like other lipids, are hydrophobic, are soluble in organic solvents and insoluble in water. Fat is an important foodstuff for many forms of life, fats serve both structural and metabolic functions, they are a necessary part of the diet of most heterotrophs and are the most energy dense, thus the most efficient form of energy storage. Some fatty acids that are set free by the digestion of fats are called essential because they cannot be synthesized in the body from simpler constituents.
There are two essential fatty acids in human nutrition: linoleic acid. Other lipids needed by the body can be synthesized from other fats. Fats and other lipids are broken down in the body by enzymes called lipases produced in the pancreas. Fats and oils are categorized according to the number and bonding of the carbon atoms in the aliphatic chain. Fats that are saturated fats have no double bonds between the carbons in the chain. Unsaturated fats have one or more double bonded carbons in the chain; the nomenclature is based on the non-acid end of the chain. This end is called the n-end, thus alpha-linolenic acid is called an omega-3 fatty acid because the 3rd carbon from that end is the first double bonded carbon in the chain counting from that end. Some oils and fats are therefore called polyunsaturated fats. Unsaturated fats can be further divided into cis fats, which are the most common in nature, trans fats, which are rare in nature. Unsaturated fats can be altered by reaction with hydrogen effected by a catalyst.
This action, called hydrogenation, tends to break all the double bonds and makes a saturated fat. To make vegetable shortening liquid cis-unsaturated fats such as vegetable oils are hydrogenated to produce saturated fats, which have more desirable physical properties e.g. they melt at a desirable temperature, store well, whereas polyunsaturated oils go rancid when they react with oxygen in the air. However, trans fats are generated during hydrogenation as contaminants created by an unwanted side reaction on the catalyst during partial hydrogenation. Saturated fats can stack themselves in a packed arrangement, so they can solidify and are solid at room temperature. For example, animal fats tallow and lard are solids. Olive and linseed oils on the other hand are liquid. Fats serve both as energy sources for the body, as stores for energy in excess of what the body needs immediately; each gram of fat when burned or metabolized releases about 9 food calories. Fats are broken down in the healthy body to release their constituents and fatty acids.
Glycerol itself can be converted to glucose by the liver and so become a source of energy. There are many different kinds of fats. All fats are derivatives of fatty acids and glycerol. Most fats are glycerides triglycerides. One chain of fatty acid is bonded to each of the three -OH groups of the glycerol by the reaction of the carboxyl end of the fatty acid with the alcohol. Water is eliminated and the carbons are linked by an -O- bond through dehydration synthesis; this process is called esterification and fats are therefore esters. As a simple visual illustration, if the kinks and angles of these chains were straightened out, the molecule would have the shape of a capital letter E; the fatty acids would each be a horizontal line. Fats therefore have "ester" bonds; the properties of any specific fat molecule depend on the particular fatty acids. Fatty acids form a family of compounds that are composed of increasing numbers of carbon atoms linked into a zig-zag chain; the more carbon atoms there are in any fatty acid, the longer its chain will be.
Long chains are more susceptible to intermolecular forces of attraction, so the longer ones melt at a higher temperature. Fatty acid chains may differ by length categorized as short to long. Short-chain fatty acids are fatty acids with aliphatic tails of fewer than six carbons. Medium-chain fatty acids are fatty acids with aliphatic tails of 6–12 carbons, which can form medium-chain triglycerides. Long-chain fatty acids are fatty acids with aliphatic tails of 13 to 21 carbons. Long chain fatty acids are fatty acids with aliphatic tails of 22 or more carbons. Any of these aliphatic fatty acid chains may be glycerated and the resultant fats may have tails of different lengths from short triformin to long, e.g. cerotic acid, or hexacosanoic acid, a 26-carbon long-chain saturated fatty acid. Long chain fats are exemplified by tallow. Most fats found in foo