Acetylajmaline esterase

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Acetylajmaline esterase
Identifiers
EC number 3.1.1.80
CAS number 110183-46-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Acetylajmaline esterase (EC 3.1.1.80, AAE, 2beta(R)-17-O-acetylajmalan:acetylesterase, acetylajmalan esterase) is an enzyme with systematic name 17-O-acetylajmaline O-acetylhydrolase.[1][2] This enzyme catalyses the following chemical reaction

(1) 17-O-acetylajmaline + H2O ajmaline + acetate
(2) 17-O-acetylnorajmaline + H2O norajmaline + acetate

This plant enzyme mediates the last stages in the biosynthesis of the indole alkaloid ajmaline.

References[edit]

  1. ^ Polz, L.; Schübel, H.; Stöckigt, J. (1987). "Characterization of 2β(R)-17-O-acetylajmalan:acetylesterase—a specific enzyme involved in the biosynthesis of the Rauwolfia alkaloid ajmaline". Z. Naturforsch. C. 42 (4): 333–342. PMID 2955586. 
  2. ^ Ruppert, M.; Woll, J.; Giritch, A.; Genady, E.; Ma, X.; Stöckigt, J. (2005). "Functional expression of an ajmaline pathway-specific esterase from Rauvolfia in a novel plant-virus expression system". Planta. 222: 888–898. doi:10.1007/s00425-005-0031-0. PMID 16133216. 

External links[edit]