Alkenylglycerophosphocholine hydrolase

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
alkenylglycerophosphocholine hydrolase
Identifiers
EC number3.3.2.2
CAS number37288-65-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, an alkenylglycerophosphocholine hydrolase (EC 3.3.2.2) is an enzyme that catalyzes the chemical reaction

1-(1-alkenyl)-sn-glycero-3-phosphocholine + H2O an aldehyde + sn-glycero-3-phosphocholine

Thus, the two substrates of this enzyme are 1-(1-alkenyl)-sn-glycero-3-phosphocholine and H2O, whereas its two products are aldehyde and sn-glycero-3-phosphocholine.

This enzyme belongs to the family of hydrolases, specifically those acting on ether bonds (ether hydrolases). The systematic name of this enzyme class is 1-(1-alkenyl)-sn-glycero-3-phosphocholine aldehydohydrolase. This enzyme is also called lysoplasmalogenase. This enzyme participates in ether lipid metabolism.

References[edit]

  • Arthur G, Page L, Mock T, Choy PC (1986). "The catabolism of plasmenylcholine in the guinea pig heart". Biochem. J. 236 (2): 475&ndash, 80. PMC 1146864. PMID 3753461.
  • Ellingson JS; Lands WEM (1968). "Phospholipid reactivation of plasmalogen metabolism". Lipids. 3 (2): 111&ndash, 120. doi:10.1007/BF02531727. PMID 17805898.
  • Warner HR; Lands WEM (1961). "The metabolism of plasmalogen: enzymatic hydrolysis of the vinyl ether" (PDF). J. Biol. Chem. 236 (9): 2404&ndash, 2409. PMID 13783189.