All-trans-phytoene synthase

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All-trans-phytoene synthase
Identifiers
EC number 2.5.1.99
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

All-trans-phytoene synthase (EC 2.5.1.99, prephytoene-diphosphate synthase, phytoene synthetase, PSase, geranylgeranyl-diphosphate geranylgeranyltransferase, 15-trans-phytoene synthase) is an enzyme with systematic name geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase (all-trans-phytoene forming).[1][2] This enzyme catalyses the following chemical reaction

2 geranylgeranyl diphosphate all-trans-phytoene + 2 diphosphate (overall reaction)
(1a) 2 geranylgeranyl diphosphate diphosphate + prephytoene diphosphate
(1b) prephytoene diphosphate all-trans-phytoene + diphosphate

This enzyme requires Mn2+ for activity.

References[edit]

  1. ^ Gregonis, D.E.; Rilling, H.C. (1974). "The stereochemistry of trans-phytoene synthesis. Some observations on lycopersene as a carotene precursor and a mechanism for the synthesis of cis- and trans-phytoene". Biochemistry. 13 (7): 1538–1542. doi:10.1021/bi00704a033. PMID 4819767. 
  2. ^ Iwata-Reuyl, D.; Math, S.K.; Desai, S.B.; Poulter, C.D. (2003). "Bacterial phytoene synthase: molecular cloning, expression, and characterization of Erwinia herbicola phytoene synthase". Biochemistry. 42 (11): 3359–3365. doi:10.1021/bi0206614. PMID 12641468. 

External links[edit]