Alpha-amyrin synthase

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Alpha-amyrin synthase
Identifiers
EC number 5.4.99.40
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Alpha-amyrin synthase (EC 5.4.99.40, 2,3-oxidosqualene alpha-amyrin cyclase, mixed amyrin synthase) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, alpha-amyrin-forming).[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene alpha-amyrin

This multifunctional enzyme produces both alpha- and beta-amyrin.

References[edit]

  1. ^ Morita, M.; Shibuya, M.; Kushiro, T.; Masuda, K.; Ebizuka, Y. (2000). "Molecular cloning and functional expression of triterpene synthases from pea (Pisum sativum) new α-amyrin-producing enzyme is a multifunctional triterpene synthase". Eur. J. Biochem. 267: 3453–3460. doi:10.1046/j.1432-1327.2000.01357.x. PMID 10848960. 

External links[edit]