Alpha-seco-amyrin synthase

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Alpha-seco-amyrin synthase
Identifiers
EC number5.4.99.52
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Alpha-seco-amyrin synthase (EC 5.4.99.52) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, alpha-seco-amyrin-forming).[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene alpha-seco-amyrin

The enzyme from Arabidopsis thaliana is multifunctional.

References[edit]

  1. ^ Shibuya, M.; Xiang, T.; Katsube, Y.; Otsuka, M.; Zhang, H.; Ebizuka, Y. (2007). "Origin of structural diversity in natural triterpenes: direct synthesis of seco-triterpene skeletons by oxidosqualene cyclase". J. Am. Chem. Soc. 129: 1450–1455. doi:10.1021/ja066873w. PMID 17263431.

External links[edit]