Alpha-seco-amyrin synthase

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Alpha-seco-amyrin synthase
Identifiers
EC number 5.4.99.52
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Alpha-seco-amyrin synthase (EC 5.4.99.52) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, alpha-seco-amyrin-forming).[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene alpha-seco-amyrin

The enzyme from Arabidopsis thaliana is multifunctional.

References[edit]

  1. ^ Shibuya, M.; Xiang, T.; Katsube, Y.; Otsuka, M.; Zhang, H.; Ebizuka, Y. (2007). "Origin of structural diversity in natural triterpenes: direct synthesis of seco-triterpene skeletons by oxidosqualene cyclase". J. Am. Chem. Soc. 129: 1450–1455. doi:10.1021/ja066873w. PMID 17263431. 

External links[edit]