Apocrine is a term used to classify exocrine glands in the study of histology. Cells which are classified as apocrine bud their secretions off through the plasma membrane producing extracellular membrane-bound vesicles; the apical portion of the secretory cell of the gland enters the lumen. It loses part of its cytoplasm in their secretions. Apocrine glands are found in the breast of lactating mammals. Secretion occurs when the release of secretory materials is accompanied with loss of part of cytoplasm. Apocrine secretion is less damaging to the gland than holocrine secretion but more damaging than merocrine secretion. An example of true apocrine glands is the mammary glands, responsible for secreting breast milk. Apocrine metaplasia is a reversible transformation of cells to an apocrine phenotype, it is common in the breast in the context of fibrocystic change. It is seen in women over the age of 50 years. Metaplasia happens. Apocrine-like cells form in a lining of developing microcysts, due to the pressure buildup within the lumen.
The pressure build up is caused by secretions. This type of metaplasia represents an exception to the common rule of metaplasia increasing the risk for developing cancer. Apocrine carcinoma is a rare form of female breast cancer; the rate of incidence varies from 0.5 to 4%. Cytologically, the cells of apocrine carcinoma are large, it has a prominent eosinophilic cytoplasm; when apocrine carcinoma is tested as a “triple negative", it means that the cells of the patient cannot express the estrogen receptor, progesterone receptor, or HER2 receptor. Diagram at uwa.edu.au
John Savile, 1st Earl of Mexborough, known as The Lord Pollington between 1753 and 1766, was a British peer and Member of Parliament. Savile was the eldest son of Charles Savile of Methley, he entered Parliament in 1747 as member for Hedon in East Yorkshire, subsequently represented New Shoreham. In 1749 he was appointed a Knight Companion of the Order of the Bath. In November 1753 he was raised to the Peerage of Ireland as Baron Pollington of Longford in the County of Longford whilst remaining an MP. In February 1766 he was created Viscount Pollington of Ferns in the County of Wexford and Earl of Mexborough of Lifford in the County of Donegal, again in the Irish peerage. Mexborough was a patron of the playwright and actor-manager Samuel Foote, he married Sarah Delaval in 1760, they had three sons: John Savile, 2nd Earl of Mexborough. Hon. Henry Savile. Hon. Charles Savile. Leigh Rayment's Peerage Pages
The Union County Vocational Technical Schools Campus is a hub for education located in Scotch Plains, New Jersey. This campus contains: Union County Vocational Technical Schools Union County Academy for Performing Arts Union County Academy for Allied Health Sciences Union County Academy for Information Technology Union County Adult Education High School Union County Magnet High School Union County Vocational-Technical High School Rutgers School of Health Related Professions Scotch Plains Campus The John H. Stamler Police Academy Plans to open what would become the Union County Vocational-Technical Schools Campus were announced in early 1966, as the new home for the Union County Vocational-Technical Institute. A 42-acre site along Raritan Road in Scotch Plains was chosen to construct three buildings, at a cost of $3.75 million. Upon opening in 1968, these buildings housed central services, the adult technical institute, the high-school aged vocational center. Campus expansions included an allied health studies building in 1973 and an expansion to the Vocational Center in 1980, focusing on special services.
After a merger with Union County College in 1982, the focus on adult classes was moved to other UCC locations in the county, leading the technical institute building to be abandoned. Beginning in the mid-1990s, a push was made to open a magnet high school on the campus. $3.5 million was spent gutting and renovating the abandoned technical institute building, which opened as the Union County Magnet High School in September 1997. Since 1997, the campus has seen a number of expansions as more high schools are built and fewer adult classes are offered; the Academy for Information Technology opened on the south side of the campus in the mid-2000s. During the same time period, the central services building was renovated and expanded to house the Academy for Allied Health Sciences; as part of the same construction project, an addition was added to the vocational center to house a new cafeteria, which would replace the one in the central services building. In the late 2000s, the Academy for Performing Arts was built on the northeast corner of the campus.
As the 2010s approached and breezeways were constructed across the campus, making it possible to walk between buildings without going outside. As of 2015, construction is underway to demolish and expand the vocational center, to house new academic classrooms
Oldfield School is a secondary school, with a small sixth form, in Newbridge, England. Since February 2011, the school has had academy status, meaning that it operates outside the control of the local authority. Prior to 2012 the main school was for girls only, with a co-educational sixth form. In 2017, the school had 1036 students aged 11 to 18. Oldfield School was founded in 1892 to serve the city of Bath. Recent buildings include a drama studio, dance studio, sports hall, a new teaching block for Mathematics and Humanities; some expansion classroom blocks date from the 1980s. The school has on-site playing fields. In the 1990s and early 2000s the school took an early opportunity to gain more independence from local authority control by becoming a grant-maintained school and a foundation school. In 2010 the school applied for academy status using the Academies Act in order to remove itself from local authority control and avoid becoming co-educational, becoming an Academy in February 2011. Under pressure from Bath and North East Somerset Council which offered to provide £1.85 million for conversion works, the school decided to become co-educational from 2012.
Recent PE teacher Helen Glover won the gold medal for the women's coxless pairs at the 2012 Summer Olympics. She took up rowing in 2008 whilst teaching at the school and trained at the Minerva Bath Rowing Club nearby. In November 2012 she returned to the school to open the £1.85 million sports centre. Penn House, or Penn Hill House, dates from the mid-1800s, it has two storeys faced with limestone ashlar, Welsh slate roofs. An Italianate villa, the building was extended to the left and rear in Baroque style in 1904 and 1924, to designs of Reginald Blomfield. Both phases of extension were under the ownership of Sir Ernest Pitman, son of Isaac Pitman and father of Isaac James Pitman; the house was designated as Grade II listed in 1994. Oldfield School was built on land to the west of the house in 1959. In the 1960s, Penn House was a separate special school, but it was absorbed into Oldfield School. Today the house is used as sixth form accommodation and by the English department; the school is a National College for School Leadership National Support School and a former Headteacher is a National Leader of Education.
The school uniform consists of a navy blue jacket with a white logo of a swan. A tie should be worn and the grey jumper is optional. A white shirt must be worn under the jumper. Students in years 7, 8, 9,10 and 11 must wear navy blue trousers or skirt. Shoes must be leather with no clear logo. In December 2013, Ofsted made a surprise inspection to investigate concerns over child safeguarding, following some complaints. Ofsted concluded that safeguarding procedures met requirements, but the school governors had an inadequate understanding of their statutory responsibilities, were overly reliant on information provided by the headteacher, an external review of governance should be undertaken. A fuller Ofsted report has not been published, despite a petition of over 1,000 signatures; the Bath Chronicle, which had seen a copy of the fuller report, reported that it "would have regraded the school rated as outstanding in 2012, which contains more serious criticisms", but was limited in what it could report for legal reasons.
In March 2014, in the week a Department for Education review team visited the school, Stuart Weatherall was appointed Chair of Governors, with the previous Chair becoming Vice-chair of Governors. The NASUWT teachers' union called for the resignation of the headteacher following the leaking of the unpublished 2013 Ofsted report which accused the headteacher of "managing staff through a culture of fear and bullying". On 30 April 2014 the headteacher resigned. On the same day it was announced that a pre-warning notice letter had been issued by the Secretary of State for Education to the governors, requiring major improvements after a serious breakdown in the way the academy had been managed and governed; the remedial actions recommended by the Education Funding Agency included the establishment of an Interim Academy Board, to take over the powers and functions of the governors for a period of time. In July 2015 the Interim Academy Board was dissolved, a normal governance regime resumed. Official website
Radha Burnier was born in Adyar, India. She was president of the Theosophical Society Adyar from 1980 until her death in 2013, she was General Secretary of the Indian Section of the Society between 1960 and 1978, was an actress in Indian films and Jean Renoir's The River. Radha Burnier was the daughter of Nilakanta Sri Srimati Bhagirathi. Shrimati Radha was educated in Theosophical schools and was a student in Rukmini Devi Arundale's school of classical Indian dance, she attended the Benares Hindu University from which she obtained a B. A. with distinction and an M. A. on Sanskrit, standing first in that University. She played a pivotal role in Jean Renoir's 1951 film The River and appeared in Indian films, billed as "Radha." She joined the Theosophical Society in 1935 and was president of youth and adult Lodges for several years. She was President of the Madras Theosophical Federation and librarian and worker at the Indian Section Headquarters of the TS, she has been a member of the General Council of the TS since 1960, has been in its Executive Committee, Finance Committee and Theosophical Publishing House Council for many years.
She lectured extensively around the world on a regular basis from 1960 and was a guest speaker at many conventions and summer schools. Radha Burnier presided over three World Congresses of the Theosophical Society: 1982 in Nairobi, Kenya. In July 1990 she conducted two well-attended seminars on "Human Regeneration" at the International Theosophical Centre in Naarden, The Netherlands, which included participants from many countries. In one of the sessions, speaking on "Regeneration and the Objects of the T. S.", she said: "Universal brotherhood, the realization of a mind in which there is no prejudice whatsoever, no barrier against anything, is regeneration, because such a consciousness is different from the ordinary consciousness." She was the author of numerous articles in The Theosophist, of which she was the editor since 1980, other Theosophical journals. She had supervised and directed the work of the Adyar Library and Research Centre since 1954 and was the editor of the Library's research journals and publications.
Radha translated Sanskrit works for publication. Radha Burnier was the Head of the Krotona Institute of Theosophy in California, she was president of the Olcott Education Society, The Theosophical Order of Service, the Besant Education Fellowship and she founded The New Life for India Movement, which promotes right citizenship, right values and right means among Indians. She had been a member of "Le Droit Humain" and became the founder and head of the Eastern Order of International Co-Freemasonry, she was a close associate of Jiddu Krishnamurti and was a Trustee of the Krishnamurti Foundation India. On 4 November 1980, at her invitation, Krishnamurti visited Adyar after an absence of 47 years, he walked with her and a number of residents from the main gate of the compound to the seashore and visited the beach where he was discovered, in 1909, by C. W. Leadbeater. Two years in December 1982, during the Adyar Centenary Convention of the TS, Krishnamurti planted a Bodhi tree at Adyar. Radha Burnier died at her home at Adyar on 31 October 2013, at 9.00 pm, following a heart attack.
She was cremated at the Besant Nagar Crematorium and her ashes were placed in the Garden of Remembrance at the TS international Headquarters at Adyar, on the spot occupied by her father's ashes. Radha Burnier was married to Raymond Burnier, a Swiss photographer, who came to India in 1932, she died at age 90, in Chennai after a prolonged illness. Human regeneration and discussions. Theosophical Publishing House, Wheaton 1991. Theosophical Publishing House, Wheaton 1985. Theosophical Publishing House, Wheaton 1993. Theosophical Publishing House, Wheaton 1985. Press release on her work in Freemasonry, 1 November 2003 Radha Burnier's obituary in the Hindu, 1 November 2013
Everett Clarence Dade is a mathematician at University of Illinois at Urbana–Champaign working on finite groups and representation theory, who introduced the Dade isometry and Dade's conjecture. The Dade isometry is an isometry from class functions on a subgroup H with support on a subset K of H to class functions on a group G, it was introduced by Dade as a generalization and simplification of an isometry used by Feit & Thompson in their proof of the odd order theorem, was used by Peterfalvi in his revision of the character theory of the odd order theorem. Dade's conjecture is a conjecture relating the numbers of characters of blocks of a finite group to the numbers of characters of blocks of local subgroups. Dade, Everett C. "Lifting group characters", Annals of Mathematics, Second Series, 79: 590–596, doi:10.2307/1970409, ISSN 0003-486X, JSTOR 1970409, MR 0160813 Feit, Characters of finite groups, W. A. Benjamin, Inc. New York-Amsterdam, MR 0219636 Feit, Walter. Dade Everett C. Dade at the Mathematics Genealogy Project