ArcLight (biology)

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ArcLight is a genetically-encoded voltage indicator (GEVI) created from Ciona intestinalis voltage sensor and the fluorescent protein super ecliptic pHluorin that carries a critical point mutation (A227D).[1]


  1. ^ Jin, Lei; Han, Zhou; Platisa, Jelena; Wooltorton, Julian R.A.; Cohen, Lawrence B.; Pieribone, Vincent A. "Single Action Potentials and Subthreshold Electrical Events Imaged in Neurons with a Fluorescent Protein Voltage Probe". Neuron. 75 (5): 779–785. doi:10.1016/j.neuron.2012.06.040. PMC 3439164Freely accessible. PMID 22958819.