Arteriovenous malformation is an abnormal connection between arteries and veins, bypassing the capillary system. This vascular anomaly is known because of its occurrence in the central nervous system, but can appear in any location. Although many AVMs are asymptomatic, they can cause intense pain or bleeding or lead to other serious medical problems. AVMs are congenital and belong to the RASopathies; the genetic transmission patterns of AVMs are incomplete, but there are known genetic mutations which can lead to an increased occurrence throughout the body. Symptoms of AVM vary according to the location of the malformation. 88% of people with an AVM are asymptomatic. The most general symptoms of a cerebral AVM include headaches and epileptic seizures, with more specific symptoms occurring that depend on the location of the malformation and the individual; such possible symptoms include: Difficulties with movement coordination, including muscle weakness and paralysis. Cerebral AVMs may present themselves in a number of different ways: Bleeding Acute onset of severe headache.

May be described as the worst headache of the patient's life. Depending on the location of bleeding, may be associated with new fixed neurologic deficit. In unruptured brain AVMs, the risk of spontaneous bleeding may be as low as 1% per year. After a first rupture, the annual bleeding risk may increase to more than 5%. Seizure or brain seizure Depending on the place of the AVM, it can cause loss of vision in one place. Headache Progressive neurologic deficit May be caused by mass venous dilatations. Presence and nature of the deficit depend on the draining veins. Pediatric patients Heart failure Macrocephaly Prominent scalp veins Pulmonary arteriovenous malformations are abnormal communications between the veins and arteries of the pulmonary circulation, leading to a right-to-left blood shunt, they have no symptoms in up to 29% of all cases, however they can give rise to serious complications including hemorrhage, infection. They are most associated with hereditary hemorrhagic telangiectasia. Can occur due to autosomal dominant diseases, such as hereditary hemorrhagic telangiectasia.

Arteries and veins are part of the vascular system. Arteries carry blood away from the heart to the lungs or the rest of the body, where the blood passes through capillaries, veins return the blood to the heart. An AVM interferes with this process by forming a direct connection of the veins. AVMs can lead to serious medical problems. Although AVMs are associated with the brain and spinal cord, they can develop in any part of the body; the arteries in the vascular system carry oxygen-rich blood, except in the case of the pulmonary artery. Structurally, arteries divide and sub-divide eventually forming a sponge-like capillary bed. Blood moves through the capillaries, giving up oxygen and taking up waste products, including CO2, from the surrounding cells. Capillaries in turn successively join together to form veins; the heart acts to uptake the venous blood. As an AVM lacks the dampening effect of capillaries on the blood flow, the AVM can get progressively larger over time as the amount of blood flowing through it increases, forcing the heart to work harder to keep up with the extra blood flow.

It causes the surrounding area to be deprived of the functions of the capillaries—removal of CO2 and delivery of nutrients to the cells. The resulting tangle of blood vessels called a nidus, has no capillaries, it can be fragile and prone to bleeding because of the abnormally direct connections between high-pressure arteries and low-pressure veins. The resultant sign, audible via stethoscope, is a rhythmic, whooshing sound caused by excessively rapid blood flow through the arteries and veins, it has been given French for noise. On some occasions, a patient with a brain AVM may become aware of the noise, which can compromise hearing and interfere with sleep in addition to causing psychological distress. AVMs are diagnosed by the following imaging methods: Computerized tomography scan is a noninvasive X-ray to view the anatomical structures within the brain to detect blood in or around the brain. A newer technology called CT angiography involves the injection of contrast into the blood stream to view the arteries of the brain.

This type of test provides the best pictures of blood vessels through angiography and soft tissues through CT. Magnetic resonance imaging scan is a noninvasive test, which uses a magnetic field and radio-frequency waves to give a detailed view of the soft tissues of the brain. Magnetic resonance angiography – scans created using magnetic resonance imaging to image the blood vessels and structures of the brain. A magnetic resonance angiogram can be an invasive procedure, involving the introduction of contrast dyes into the vasculature of a patient using a catheter inserted into an artery and passed through the blood ves

Tunji Femi Awojobi is a retired Nigerian professional basketball player. A former boxer, Awojobi graduated from Boston University in 1997. Following graduation, he played in several European countries, most notably in Israel. Awojobi was a member of the Nigerian national team, he participated in the 1998 and 2006 FIBA World Championship, his best achievement in European basketball was winning the ULEB cup as the starting Center for Hapoel Jerusalem from Israel. In the finals Jerusalem beat Real Madrid 83:72. Awojobi played college basketball at Boston University for four years, he is the first player in New England college basketball history to record 2,000 points and 1,000 rebounds. Awojobi concluded his outstanding career as just one of five Division I players to register career totals of 2,000 points, 1,000 rebounds, 300 blocked shots, he joined a select group composed of Alonzo Mourning, Pervis Ellison, Derrick Coleman, David Robinson. Awojobi established 13 BU records, including points, blocked shots, field goals.

His rebounding and scoring totals rank among the best in the history of the America East. In 1996–97, Awojobi led BU to a school-record 25 victories and America East regular-season and tournament titles, to the NCAA tournament. In recognition of his efforts, Awojobi was a four-time team MVP and first-team all-conference selection. In his senior year, he was named the league's Player of the Year as well as the MVP of the conference's tournament, while adding New England Division I Player of the Year and first-team All-ECAC honors, he was inducted into the BU Hall of Fame in 2002. List of NCAA Division I men's basketball players with 2000 points and 1000 rebounds Hall of Fame - Tunji Awojobi Tunji Awojobi at tblstat.net Tunji Awojobi at euroleague.net Tunji Awojobi at adriaticbasket.com

The Desmond Stakes is a Group 3 flat horse race in Ireland open to thoroughbreds aged three years or older. It is run at Leopardstown over a distance of 1 mile, it is scheduled to take place each year in August; the event is named after Desmond, a champion sire in 1913. It was held at the Curragh, it used to be known as the Desmond Plate; the race was transferred to Leopardstown in 2002. It has continued at this venue with one exception, a temporary return to the Curragh in 2009. Horse racing in Ireland List of Irish flat horse races Paris-Turf: "1983". "1984". "1985". "1986". "1987". Racing Post: 1988, 1989, 1990, 1991, 1992, 1993, 1994, 1995, 1996, 1997 1998, 1999, 2000, 2001, 2002, 2003, 2004, 2005, 2006, 2007 2008, 2009, 2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017 2018, 2019 galopp-sieger.de – Desmond Stakes. Ifhaoneline.org – International Federation of Horseracing Authorities – Desmond Stakes. Irishracinggreats.com – Desmond Stakes. Pedigreequery.com – Desmond Stakes

Zainab Chottani is a Pakistan based fashion designer who started as a bridal wear designer but has included prêt and haute couture in her forte. She is one of the well known designers in Pakistan for bridal wear and has displayed her creations in Pakistan as well as in Dubai, USA and London. Chottani started in bridal fashion under the name of Zainab Sajid in 1999, she uses embroidery along with different cuts to form new designs. The designs contain influences from the Mughal Era where Royal women adorned decorated dresses to look more attractive, her bridal dresses are made to order as to cater to the different requirements of each bride. She has displayed her bridal collection in various exhibitions including the Pantene Bridal Couture week and Pakistan Fashion Week by Riwayat in the UK. Zainab Chottani has added to her portfolio by introducing the brands Mera Pakistan. Aqua is a fashion label. Launched in 2012, the brand makes clothes to be worn in the summer season by featuring bright colors and baggy shirts.

It launched the Mera Pakistan collection in March 2012 which aimed to convert Pakistan’s cultural symbols into fashion. It did this by featuring rickshaws, traditional drums, the Minar-e-Pakistan on its kurta’s, a long shirt worn by women in Pakistan. Chottani did her first show in 2010 with Frieha Altaf, has showcased her work during the Pakistan Fashion Week and Bridal Couture Week. Creations from the house of Zainab Chottani have been displayed in various fashion shows. Models adorned her work in the Pakistan Fashion week in London alongside notable designers such as Sonya Battla, Sophia Mehta and Rizwan Ahmad, her work was displayed at the Pantene Bridal Couture Week where her notable personalities such as TV hosts Shaista Wahidi, Nida Yasir, Fahad Mustafa walked the ramp wearing her works with super model Nadia Hussain to follow. Apart from these shows, Chottani’s work has been showcased in Dubai and at her studio in which she introduces new lines of work. Zainab Chottani Lawn 2017 Official website

Joseph Zatzman, CM was a Canadian businessman and politician who served as Mayor of Dartmouth, Nova Scotia from 1964 to 1967. He was instrumental in the development of Burnside Industrial Park in the 1960s and a central thoroughfare in the Park is named Joseph Zatzman Drive in his honour. Zatzman was the only Jewish mayor in Dartmouth's history, he was invested as Member of the Order of Canada in October 1997. The Dartmourth Sportsplex, an indoor sports and community centre, opened 1982 was re-named the Zatzman Sportsplex in 2019 in honour of the former Mayor. Born in Saint John, N. B. in 1912, he was the first-born son of Ida Zatzman. He graduated from Halifax Academy and attended Dalhousie University in the Bachelor of Commerce program; when the Great Depression began he moved to Dartmouth. In 1934, aged 22 years old, Joseph Zatzman started his career as an entrepreneur, purchasing a small grocery store on the corner of Portland St. and Victoria Rd. in Dartmouth known as Community Groceteria.

Following the sale of Community Groceteria to the Sobey Family, Zatzman entered the real estate business, under the name of Maplehurst Apartments, building a number of modern apartment buildings on the Dartmouth harbourfront. During the 1930s, Zatzman became a community leader and active member of Nova Scotia's Jewish community and was recruited by the Jewish Immigration Aid Society to volunteer to help immigrants arriving at Pier 21. By the mid-1950s, the company had more than 200 apartments and had become one of the largest property management companies in Nova Scotia; the Royal Bank building in Dartmouth and the Dartmouth Professional Centre were both managed and built by Maplehurst. In 1956 he became the president of the Dartmouth Chamber of Commerce, the following year was elected to the Town Council, for the first of four terms. Zatzman was elected as mayor of Dartmouth in 1963, becoming the only Jewish mayor in the community's history. Zatzman's swearing-in took place in Dartmouth's Old City Hall in 1964.

The ceremony was officiated by Lieutenant Governor of Nova Scotia Henry Poole MacKeen. The signature achievement of Zatzman's mayoralty was the establishment of Burnside Industrial Park. Following his mayoralty, served as chairman of the Nova Scotia Resources Development Board and as vice-chair of Saint Mary's University's board of governors. Zatzman had many other community involvements and chairmanships following his time in municipal politics, including the Dartmouth Chamber of Commerce, the Atlantic Provinces Chamber of Commerce, United Jewish Appeal, Atlantic Jewish Council, the Regional Authority. Zatzman received an Honorary Degree from Saint Mary's in a Doctor of Laws, he was a former Governor of the Saint Mary's Senate. In October, 1997, he was inducted into the Order of Canada, his citation touched upon his work as Mayor around the creation of the Burnside Industrial Park, which the citation noted now represents fifty-percent of all commercial space in Atlantic Canada. Zatzman died at the age of 95 on December 10, 2007 and was survived by sister Mrs. Liilian Aronson and children, Michael Zatzman and Karla Zatzman.

Mayor Zatzman was predeceased by younger siblings Mrs. Betty Astroff and Mr. Myer Zatzman, wife Mrs. Leah Flam Zatzman. In 2019, the Dartmouth Sportsplex was re-named the Zatzman Sportsplex in honour of Mayor Zatzman

Lucimara Silvestre da Silva is a Brazilian track and field athlete who competes in the heptathlon. She represented her country at the 2008 Beijing Olympics and competed at the World Championships in Athletics in 2007, her personal best of 6076 points is the South American record for the event. Following her first national title in 2005, da Silva emerged in 2007, she repeated as the continental champion in 2009, but was stripped of the title and banned for two years after she failed a drug test for the banned substance Erythropoietin. She began her career as a specialist in horizontal jumps, she was the sprint hurdles champion and long jump runner-up at the 2002 South American Youth Championships in Athletics and went on to win the hurdles at the 2003 South American Junior Championships in Athletics, where she was fifth in the triple jump. She took up the heptathlon in 2004 and made her breakthrough at the national level the following year, winning the Brazil championships with a personal best of 5378 points.

In her first international appearance in the combined events, she came fourth overall at the 2005 South American Championships in Athletics. The following year she competed in Europe for the first time, gaining 4584 points at the Multistars meet in Desenzano del Garda, she improved her best to 5611 points on home turf in São Paulo and demonstrated her versatility at the 2006 Lusophony Games the following month, claiming the hurdles title and helping the Brazilian women to gold medals in the 100 and 400 m relay events. Following a personal best score of 5897 points for fourth at the 2007 Multistars meeting, her first continental title came at the 2007 South American Championships in Athletics in São Paulo, her mark of 5803 points was a new championship record and she managed a bronze medal in the 100 m hurdles at the competition. She scored over 5800 points again at July's Pan American Games and claimed the bronze medal behind Jessica Zelinka and Gretchen Quintana; as her continent's only representative in the women's heptathlon at the 2007 World Championships in Athletics, she finished in 31st place.

Da Silva achieved the Olympic qualifying standard in April 2008, setting a best of 5906 points in Rio de Janeiro. She won the heptathlon gold medal at the 2008 Ibero-American Championships, but did not fare as well at the national championships that month, as she ended up in fourth. Representing Brazil at the 2008 Beijing Olympics, she came seventeenth in the heptathlon event but broke Conceição Geremias' 25-year-old South American record with her total of 6076 points, she won at the Brazilian Championships in 2009 with a score of 5884 points and improved her own meet record to win the 2009 South American Championships in Athletics. However, this mark did not stand as she had failed a doping test in the days prior to the competition, testing positive for the banned substance Recombinant EPO, her coach, Jayme Netto, admitted. She was stripped of her South American title and banned from the sport for two years for the doping infraction. Lucimara da Silva gave birth to her first daughter, Sellena, in December 2013, her second daughter, Mia, in May 2016.

List of doping cases in athletics Lucimara da Silva at World Athletics