1.
Venture capital
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Venture capital firms or funds invest in these early-stage companies in exchange for equity–an ownership stake–in the companies they invest in. Venture capitalists take on the risk of financing risky start-ups in the hopes some of the firms they support will become successful. The start-ups are usually based on a technology or business model and they are usually from the high technology industries, such as information technology. The typical venture capital investment occurs after a seed funding round. The first round of venture capital to fund growth is called the Series A round. This institution helps identify promising new firms and provide them with finance, technical expertise, mentoring, marketing know-how, and business models. Once integrated into the network, these firms are more likely to succeed. However, venture capitalists decisions are often biased, exhibiting for instance overconfidence and illusion of control, a venture may be defined as a project prospective converted into a process with an adequate assumed risk and investment. With few exceptions, private equity in the first half of the 20th century was the domain of wealthy individuals, the Wallenbergs, Vanderbilts, Whitneys, Rockefellers, and Warburgs were notable investors in private companies in the first half of the century. In 1938, Laurance S. Rockefeller helped finance the creation of both Eastern Air Lines and Douglas Aircraft, and the Rockefeller family had vast holdings in a variety of companies. Eric M. Warburg founded E. M. Warburg & Co. in 1938, which would ultimately become Warburg Pincus, with investments in both leveraged buyouts and venture capital. The Wallenberg family started Investor AB in 1916 in Sweden and were early investors in several Swedish companies such as ABB, Atlas Copco, Ericsson, before World War II, money orders remained primarily the domain of wealthy individuals and families. Georges Doriot, the father of capitalism, founded INSEAD in 1957. Along with Ralph Flanders and Karl Compton, Doriot founded ARDC in 1946 to encourage investment in businesses run by soldiers returning from World War II. ARDC became the first institutional private-equity investment firm to raise capital from other than wealthy families. ARDC is credited with the first trick when its 1957 investment of $70,000 in Digital Equipment Corporation would be valued at over $355 million after the initial public offering in 1968. Former employees of ARDC went on to several prominent venture-capital firms including Greylock Partners and Morgan, Holland Ventures. ARDC continued investing until 1971, when Doriot retired, in 1972 Doriot merged ARDC with Textron after having invested in over 150 companies
2.
Cambridge, Massachusetts
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Cambridge is a city in Middlesex County, Massachusetts, and is a part of the Boston metropolitan area. According to the 2010 Census, the population was 105,162. As of July 2014, it was the fifth most populous city in the state, behind Boston, Worcester, Springfield, Cambridge was one of the two seats of Middlesex County prior to the abolition of county government in 1997, Lowell was the other. The site for what would become Cambridge was chosen in December 1630, because it was located safely upriver from Boston Harbor, Thomas Dudley, his daughter Anne Bradstreet, and her husband Simon, were among the first settlers of the town. The first houses were built in the spring of 1631, the settlement was initially referred to as the newe towne. Official Massachusetts records show the name capitalized as Newe Towne by 1632, the original village site is in the heart of todays Harvard Square. In the late 19th century, various schemes for annexing Cambridge itself to the city of Boston were pursued and rejected, in 1636, the Newe College was founded by the colony to train ministers. Newe Towne was chosen for the site of the college by the Great and General Court primarily—according to Cotton Mather—to be near the popular, in May 1638 the name of the settlement was changed to Cambridge in honor of the university in Cambridge, England. Hooker and Shepard, Newtownes ministers, and the colleges first president, major benefactor, in 1629, Winthrop had led the signing of the founding document of the city of Boston, which was known as the Cambridge Agreement, after the university. It was Governor Thomas Dudley who, in 1650, signed the charter creating the corporation which still governs Harvard College, Cambridge grew slowly as an agricultural village eight miles by road from Boston, the capital of the colony. By the American Revolution, most residents lived near the Common and Harvard College, with farms and estates comprising most of the town. Coming up from Virginia, George Washington took command of the volunteer American soldiers camped on Cambridge Common on July 3,1775, most of the Tory estates were confiscated after the Revolution. On January 24,1776, Henry Knox arrived with artillery captured from Fort Ticonderoga, a second bridge, the Canal Bridge, opened in 1809 alongside the new Middlesex Canal. The new bridges and roads made what were formerly estates and marshland into prime industrial and residential districts, in the mid-19th century, Cambridge was the center of a literary revolution when it gave the country a new identity through poetry and literature. Cambridge was home to some of the famous Fireside Poets—so called because their poems would often be read aloud by families in front of their evening fires, the Fireside Poets—Henry Wadsworth Longfellow, James Russell Lowell, and Oliver Wendell Holmes—were highly popular and influential in their day. Cambridge was incorporated as a city in 1846, the citys commercial center began to shift from Harvard Square to Central Square, which became the downtown of the city around this time. The coming of the railroad to North Cambridge and Northwest Cambridge then led to three changes in the city, the development of massive brickyards and brickworks between Massachusetts Ave. For many decades, the citys largest employer was the New England Glass Company, by the middle of the 19th century it was the largest and most modern glassworks in the world
3.
United States
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Forty-eight of the fifty states and the federal district are contiguous and located in North America between Canada and Mexico. The state of Alaska is in the northwest corner of North America, bordered by Canada to the east, the state of Hawaii is an archipelago in the mid-Pacific Ocean. The U. S. territories are scattered about the Pacific Ocean, the geography, climate and wildlife of the country are extremely diverse. At 3.8 million square miles and with over 324 million people, the United States is the worlds third- or fourth-largest country by area, third-largest by land area. It is one of the worlds most ethnically diverse and multicultural nations, paleo-Indians migrated from Asia to the North American mainland at least 15,000 years ago. European colonization began in the 16th century, the United States emerged from 13 British colonies along the East Coast. Numerous disputes between Great Britain and the following the Seven Years War led to the American Revolution. On July 4,1776, during the course of the American Revolutionary War, the war ended in 1783 with recognition of the independence of the United States by Great Britain, representing the first successful war of independence against a European power. The current constitution was adopted in 1788, after the Articles of Confederation, the first ten amendments, collectively named the Bill of Rights, were ratified in 1791 and designed to guarantee many fundamental civil liberties. During the second half of the 19th century, the American Civil War led to the end of slavery in the country. By the end of century, the United States extended into the Pacific Ocean. The Spanish–American War and World War I confirmed the status as a global military power. The end of the Cold War and the dissolution of the Soviet Union in 1991 left the United States as the sole superpower. The U. S. is a member of the United Nations, World Bank, International Monetary Fund, Organization of American States. The United States is a developed country, with the worlds largest economy by nominal GDP. It ranks highly in several measures of performance, including average wage, human development, per capita GDP. While the U. S. economy is considered post-industrial, characterized by the dominance of services and knowledge economy, the United States is a prominent political and cultural force internationally, and a leader in scientific research and technological innovations. In 1507, the German cartographer Martin Waldseemüller produced a map on which he named the lands of the Western Hemisphere America after the Italian explorer and cartographer Amerigo Vespucci
4.
Venture capital fund
–
Venture capital firms or funds invest in these early-stage companies in exchange for equity–an ownership stake–in the companies they invest in. Venture capitalists take on the risk of financing risky start-ups in the hopes some of the firms they support will become successful. The start-ups are usually based on a technology or business model and they are usually from the high technology industries, such as information technology. The typical venture capital investment occurs after a seed funding round. The first round of venture capital to fund growth is called the Series A round. This institution helps identify promising new firms and provide them with finance, technical expertise, mentoring, marketing know-how, and business models. Once integrated into the network, these firms are more likely to succeed. However, venture capitalists decisions are often biased, exhibiting for instance overconfidence and illusion of control, a venture may be defined as a project prospective converted into a process with an adequate assumed risk and investment. With few exceptions, private equity in the first half of the 20th century was the domain of wealthy individuals, the Wallenbergs, Vanderbilts, Whitneys, Rockefellers, and Warburgs were notable investors in private companies in the first half of the century. In 1938, Laurance S. Rockefeller helped finance the creation of both Eastern Air Lines and Douglas Aircraft, and the Rockefeller family had vast holdings in a variety of companies. Eric M. Warburg founded E. M. Warburg & Co. in 1938, which would ultimately become Warburg Pincus, with investments in both leveraged buyouts and venture capital. The Wallenberg family started Investor AB in 1916 in Sweden and were early investors in several Swedish companies such as ABB, Atlas Copco, Ericsson, before World War II, money orders remained primarily the domain of wealthy individuals and families. Georges Doriot, the father of capitalism, founded INSEAD in 1957. Along with Ralph Flanders and Karl Compton, Doriot founded ARDC in 1946 to encourage investment in businesses run by soldiers returning from World War II. ARDC became the first institutional private-equity investment firm to raise capital from other than wealthy families. ARDC is credited with the first trick when its 1957 investment of $70,000 in Digital Equipment Corporation would be valued at over $355 million after the initial public offering in 1968. Former employees of ARDC went on to several prominent venture-capital firms including Greylock Partners and Morgan, Holland Ventures. ARDC continued investing until 1971, when Doriot retired, in 1972 Doriot merged ARDC with Textron after having invested in over 150 companies
5.
Assets under management
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Methods of calculating AUM vary between firms. The fee structure depends on the contract between each client and the firm or fund, Assets under management rise and fall. They may increase when investment performance is positive, or when new customers, rising AUM normally increases the fees which the firm generates. Conversely, AUM are reduced by negative investment performance, as well as redemptions or withdrawals, including fund closures, client defections, lower AUM tend to result in lower fees generated. Assets under management includes, Capital raised from investors, Capital belonging to the principals of the management firm. For example, if fund managers contribute $2B of their own capital to the fund and raise additional $10B from investors, net asset value Fund Management Activities Survey 2005 Sovereign Wealth Fund Assets Under Management
6.
Accomplice (company)
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Accomplice is one of the most active early stage firms in New England. A majority of Accomplice’s investments are in Boston, with others throughout the U. S. in Canada, Accomplice is headquartered in Cambridge, Massachusetts. Formerly known as Atlas Venture, the firm announced in October 2014 that it was splitting its technology, the technology group renamed as Accomplice, the life sciences group retained the name Atlas Venture. The technology group, then operating as FKA, crowdsourced its search for a new name in March 2015, “Accomplice” was chosen and the individual who pitched the name won a $25,000 investment in the new fund and $25,000 to donate to a TUGG nonprofit. Accomplice’s partners Jeff Fagnan and Ryan Moore have invested in over 180 companies, the Accomplice partners raised over $3.0 billion investor commitments across nine funds as part of Atlas Venture. In March 2015, Accomplice closed its tenth fund and its first under its new name with an oversubscribed $200 million tech-only fund, Accomplice Chris Lynch, Accomplice Partner, blog
7.
Life sciences
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While biology remains the centerpiece of the life sciences, technological advances in molecular biology and biotechnology have led to a burgeoning of specializations and interdisciplinary fields. Some life sciences focus on a type of life. For example, zoology is the study of animals, while botany is the study of plants, other life sciences focus on aspects common to all or many life forms, such as anatomy and genetics. Yet other fields are interested in technological advances involving living things, another major, though more specific, branch of life sciences involves understanding the mind – neuroscience. The life sciences are helpful in improving the quality and standard of life and they have applications in health, agriculture, medicine, and the pharmaceutical and food science industries. There is considerable overlap between many of the topics of study in the life sciences, biology – burst and eclectic field, composed of many branches and subdisciplines. However, despite the broad scope of biology, there are general and unifying concepts within it that govern all study and research, consolidating it into a single. In general, biology recognizes the cell as the unit of life, genes as the basic unit of heredity. It is also understood today that all organisms survive by consuming and transforming energy and by regulating their internal environment to maintain a stable, hematology – study of blood and blood-forming organs. Toxicology - study of the effects of chemicals on living organisms Zoology – study of animals, including classification, physiology, development, medicine – applied science or practice of the diagnosis, treatment, and prevention of disease. It encompasses a variety of care practices evolved to maintain and restore health by the prevention. Some of its branches are, Anesthesiology – branch of medicine that deals with life support, cardiology – branch of medicine that deals with disorders of the heart and the blood vessels. Critical care medicine – focuses on support and the intensive care of the seriously ill. Dermatology – branch of medicine that deals with the skin, its structure, functions, emergency medicine – focuses on care provided in the emergency department. Endocrinology – branch of medicine that deals with disorders of the endocrine system, gastroenterology – branch of medicine that deals with the study and care of the digestive system. General Practice is a branch of medicine that specializes in primary care, geriatrics – branch of medicine that deals with the general health and well-being of the elderly. Gynecology – branch of medicine that deals with the health of the reproductive systems. Hematology – branch of medicine that deals with the blood and the circulatory system, hepatology – branch of medicine that deals with the liver, gallbladder and the biliary system
8.
Startup company
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A startup is usually a company such as a small business, a partnership or an organization designed to rapidly develop a scalable business model. Startup companies can come in all forms and sizes, some of the critical tasks are to build a co-founder team to secure key skills, know-how, financial resources and other elements to conduct research on the target market. Typically, a startup will begin by building a first minimum viable product, in addition, startups founders do research to deepen their understanding of the ideas, technologies or business concepts and their commercial potential. Business models for startups are generally found via a bottom-up or top-down approach, given that startups operate in high-risk sectors, it can also be hard to attract investors to support the product/service development or attract buyers. The size and maturity of the startup ecosystem where the startup is launched, the startup ecosystem consists of the individuals, institutions and organizations business incubators and business accelerators and top-performing entrepreneurial firms and startups. A region with all of elements is considered to be a strong entrepreneurship ecosystem. Investors are generally most attracted to new companies distinguished by their strong co-founding team. Attractive startups generally have lower bootstrapping costs, higher risk, successful startups are typically more scalable than an established business, in the sense that the startup has the potential to grow rapidly with a limited investment of capital, labor or land. Startups have several options for funding, venture capital firms and angel investors may help startup companies begin operations, exchanging seed money for an equity stake in the firm. Venture capitalists and angel investors provide financing to a range of startups, with the expectation that a small number of the startups will become viable. Factoring is another option, though it is not unique to startups, startups usually need to form partnerships with other firms to enable their business model to operate. To become attractive to businesses, startups need to align their internal features, such as management style. In their 2013 study, Kask and Linton develop two ideal profiles, or also known as configurations or archetypes, for startups that are commercializing inventions, the inheritor profile calls for management style that is not too entrepreneurial and the startup should have an incremental invention. This profile is set out to be successful in a market that has a dominant design. In contrast to this profile is the originator which has a management style that is highly entrepreneurial and this profile is set out to be more successful in a market that does not have a dominant design. New startups should align themselves to one of the profiles when commercializing an invention to be able to find, by finding a business partner a startup will have greater chances to become successful. Startup founders often have a casual or offbeat attitude in their dress, office space and marketing. Startup founders in the 2010s may wear hoodies, sneakers and other clothes to business meetings
9.
Seattle
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Seattle is a seaport city on the west coast of the United States and the seat of King County, Washington. With an estimated 684,451 residents as of 2015, Seattle is the largest city in both the state of Washington and the Pacific Northwest region of North America. In July 2013, it was the major city in the United States. The city is situated on an isthmus between Puget Sound and Lake Washington, about 100 miles south of the Canada–United States border, a major gateway for trade with Asia, Seattle is the fourth-largest port in North America in terms of container handling as of 2015. The Seattle area was inhabited by Native Americans for at least 4,000 years before the first permanent European settlers. Arthur A. Denny and his group of travelers, subsequently known as the Denny Party, arrived from Illinois via Portland, the settlement was moved to the eastern shore of Elliott Bay and named Seattle in 1852, after Chief Siahl of the local Duwamish and Suquamish tribes. Logging was Seattles first major industry, but by the late-19th century, growth after World War II was partially due to the local Boeing company, which established Seattle as a center for aircraft manufacturing. The Seattle area developed as a technology center beginning in the 1980s, in 1994, Internet retailer Amazon was founded in Seattle. The stream of new software, biotechnology, and Internet companies led to an economic revival, Seattle has a noteworthy musical history. From 1918 to 1951, nearly two dozen jazz nightclubs existed along Jackson Street, from the current Chinatown/International District, to the Central District, the jazz scene developed the early careers of Ray Charles, Quincy Jones, Ernestine Anderson, and others. Seattle is also the birthplace of rock musician Jimi Hendrix and the alternative rock subgenre grunge, archaeological excavations suggest that Native Americans have inhabited the Seattle area for at least 4,000 years. By the time the first European settlers arrived, the people occupied at least seventeen villages in the areas around Elliott Bay, the first European to visit the Seattle area was George Vancouver, in May 1792 during his 1791–95 expedition to chart the Pacific Northwest. In 1851, a party led by Luther Collins made a location on land at the mouth of the Duwamish River. Thirteen days later, members of the Collins Party on the way to their claim passed three scouts of the Denny Party, members of the Denny Party claimed land on Alki Point on September 28,1851. The rest of the Denny Party set sail from Portland, Oregon, after a difficult winter, most of the Denny Party relocated across Elliott Bay and claimed land a second time at the site of present-day Pioneer Square, naming this new settlement Duwamps. For the next few years, New York Alki and Duwamps competed for dominance, david Swinson Doc Maynard, one of the founders of Duwamps, was the primary advocate to name the settlement after Chief Sealth of the Duwamish and Suquamish tribes. The name Seattle appears on official Washington Territory papers dated May 23,1853, in 1855, nominal land settlements were established. On January 14,1865, the Legislature of Territorial Washington incorporated the Town of Seattle with a board of managing the city
