Beta-farnesene synthase

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Beta-farnesene synthase
EC number
IntEnz IntEnz view
ExPASy NiceZyme view
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Beta-farnesene synthase (EC, farnesene synthase, terpene synthase 10, terpene synthase 10-B73, TPS10) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((E)-beta-farnesene-forming).[1][2][3][4][5][6][7][8] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (E)-beta-farnesene + diphosphate


  1. ^ Zhao, B.; Lei, L.; Vassylyev, D.G.; Lin, X.; Cane, D.E.; Kelly, S.L.; Yuan, H.; Lamb, D.C.; Waterman, M.R. (2009). "Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site". J. Biol. Chem. 284: 36711–36719. doi:10.1074/jbc.M109.064683. PMC 2794785Freely accessible. PMID 19858213. 
  2. ^ Picaud, S.; Brodelius, M.; Brodelius, P.E. (2005). "Expression, purification and characterization of recombinant (E)-β-farnesene synthase from Artemisia annua". Phytochemistry. 66 (9): 961–967. doi:10.1016/j.phytochem.2005.03.027. PMID 15896363. 
  3. ^ Kollner, T.G.; Gershenzon, J.; Degenhardt, J. (2009). "Molecular and biochemical evolution of maize terpene synthase 10, an enzyme of indirect defense". Phytochemistry. 70 (9): 1139–1145. doi:10.1016/j.phytochem.2009.06.011. PMID 19646721. 
  4. ^ Schnee, C.; Kollner, T.G.; Held, M.; Turlings, T.C.; Gershenzon, J.; Degenhardt, J. (2006). "The products of a single maize sesquiterpene synthase form a volatile defense signal that attracts natural enemies of maize herbivores". Proc. Natl. Acad. Sci. USA. 103 (4): 1129–1134. doi:10.1073/pnas.0508027103. PMC 1347987Freely accessible. PMID 16418295. 
  5. ^ Maruyama, T.; Ito, M.; Honda, G. (2001). "Molecular cloning, functional expression and characterization of (E)-β farnesene synthase from Citrus junos". Biol. Pharm. Bull. 24 (10): 1171–1175. doi:10.1248/bpb.24.1171. PMID 11642326. 
  6. ^ Crock, J.; Wildung, M.; Croteau, R. (1997). "Isolation and bacterial expression of a sesquiterpene synthase cDNA clone from peppermint (Mentha × piperita, L.) that produces the aphid alarm pheromone (E)-β-farnesene". Proc. Natl. Acad. Sci. USA. 94 (24): 12833–12838. doi:10.1073/pnas.94.24.12833. PMC 24224Freely accessible. PMID 9371761. 
  7. ^ Schnee, C.; Kollner, T.G.; Gershenzon, J.; Degenhardt, J. (2002). "The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-β-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage". Plant Physiol. 130 (4): 2049–2060. doi:10.1104/pp.008326. PMC 166716Freely accessible. PMID 12481088. 
  8. ^ Huber, D.P.W.; Philippe, R.N.; Godard, K.-A.; Sturrock, R.N.; Bohlmann, J. (2005). "Characterization of four terpene synthase cDNAs from methyl jasmonate-induced Douglas-fir, Pseudotsuga menziesii". Phytochemistry. 66 (12): 1427–1439. doi:10.1016/j.phytochem.2005.04.030. PMID 15921711. 

External links[edit]