Centaureidin

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Centaureidin
Chemical structure of centaureidin
Names
IUPAC name
5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6-dimethoxychromen-4-one
Other names
Desmethoxycentaureidine
5,7,3'-Trihydroxy-3,6,4'-trimethoxyflavone
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
Properties
C18H16O8
Molar mass 360.31 g/mol
Density 1.542 g/mL
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is ☑Y☒N ?)
Infobox references

Centaureidin is an O-methylated flavonol. It can be isolated from Tanacetum microphyllum,[1] Brickellia veronicaefolia, Bidens pilosa[2] and Polymnia fruticosa.[3]

References[edit]

  1. ^ Abad, Maria Jose; Bermejo, Paulina; Villar, Angel (1995). "The activity of flavonoids extracted from Tanacetum microphyllum DC. (Compositae) on soybean lipoxygenase and prostaglandin synthetase". General Pharmacology: the Vascular System. 26 (4): 815–9. doi:10.1016/0306-3623(94)00242-F. PMID 7635257. 
  2. ^ Chang, Shu-Lin; Chiang, Yi-Ming; Chang, Cicero Lee-Tian; Yeh, Hsu-Hua; Shyur, Lie-Fen; Kuo, Yueh-Hsiung; Wu, Tung-Kung; Yang, Wen-Chin (2007). "Flavonoids, centaurein and centaureidin, from Bidens pilosa, stimulate IFN-γ expression". Journal of Ethnopharmacology. 112 (2): 232–6. doi:10.1016/j.jep.2007.03.001. PMID 17408892. 
  3. ^ Beutler, John A.; Cardellina, John H.; Lin, Chii M.; Hamel, Ernest; Cragg, Gordon M.; Boyd, Michael R. (1993). "Centaureidin, a cytotoxic flavone from Polymnia fruticosa, inhibits tubulin polymerization". Bioorganic & Medicinal Chemistry Letters. 3 (4): 581–4. doi:10.1016/S0960-894X(01)81233-6.