Channelosome

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search

The channelosome (not to be confused with "channelome") is the collection of (usually) signalling proteins associated with an ion channel. The channelosome is frequently clustered within a lipid microdomain or caveolae. This collection of proteins may be involved with anchoring, phosphorylation or some other modulatory or support function. An example is neural KCNQ/M (Kv7) potassium channelosome (see Delmas & Brown, 2005).

References[edit]

Delmas, P.; Brown, D. A. (2005). "Pathways modulating neural KCNQ/M (Kv7) potassium channels". Nature Reviews Neuroscience. 6 (11): 850–62. doi:10.1038/nrn1785. PMID 16261179.