Clayton is a suburb in Melbourne, Victoria, Australia, 19 km south-east of Melbourne's Central Business District, located within the City of Monash local government area. Clayton recorded a population of 18,988 at the 2021 census.

Clayton railway station is a commuter railway station located in the suburb of Clayton, in the south-eastern suburbs of Melbourne, Victoria, Australia. The station originally opened in 1880 as "Clayton's Road". It did not receive its current name until 1890. The station consists of a single island platform connected to the station concourse on Clayton Road via escalators, lifts and a staircase. The station was previously at grade; however, in 2018, a new elevated station was rebuilt as part of the Level Crossing Removal Project.