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Combination of
Estradiol benzoateEstrogen
Estradiol dienanthateEstrogen
Testosterone enanthate benzilic acid hydrazoneAndrogen/anabolic steroid
Clinical data
Trade namesClimacteron
Routes of
Intramuscular injection
CAS Number
PubChem CID

Climacteron is a combination formulation of 1.0 mg estradiol benzoate, 7.5 mg estradiol dienanthate, and 150 mg testosterone enanthate benzilic acid hydrazone (69 mg testosterone base) which is used in the treatment of menopausal symptoms in postmenopausal women.[1][2] It is administered by intramuscular injection and is given once every 4 to 8 weeks or less frequently.[1]

See also[edit]


  1. ^ a b
  2. ^ Sherwin BB (1988). "Estrogen and/or androgen replacement therapy and cognitive functioning in surgically menopausal women". Psychoneuroendocrinology. 13 (4): 345–57. doi:10.1016/0306-4530(88)90060-1. PMID 3067252.