Condensation reaction

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A condensation reaction is a class of an organic addition reaction that proceeds in a step-wise fashion to produce the addition product, usually in equilibrium, and a water molecule (hence named condensation), the reaction may otherwise involve the formation of ammonia, ethanol, or acetic acid.[1] It is a versatile class of reactions that can occur in acidic or basic conditions or in the presence of a catalyst, this class of reactions is a vital part of life as it is essential to the formation of peptide bonds between amino acids and the biosynthesis of fatty acids.[2]

Many variations of condensation reactions exist, common examples include the aldol condensation, Claisen condensation, Knoevenagel condensation, and the Dieckman condensation (intramolecular Claisen condensation).[3]

Condensation reaction between two symmetrical aldehydes. The final product is formed irreversibly due to stability from the conjugation of the double bonds

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References[edit]

  1. ^ "Condensation Reaction". IUPAC Copendium of Chemical Terminology (Gold Book). IUPAC. Retrieved 7 December 2017. 
  2. ^ Voet, Donald; Voet, Judith; Pratt, Chriss (2008). Fundamentals of Biochemistry. Hoboken, NJ: John Wiley & Sons, Inc. p. 88. ISBN 978-0470-12930-2. 
  3. ^ Bruckner, Reinhard (2002). Advanced Organic Chemistry (First ed.). San Diego, California: Harcourt Academic Press. pp. 414–427. ISBN 0-12-138110-2.