The Manhattan Project was a research and development undertaking during World War II that produced the first nuclear weapons. It was led by the United States with the support of Canada. From 1942 to 1946, the project was under the direction of Major General Leslie Groves of the U. S. Army Corps of Engineers. Nuclear physicist Robert Oppenheimer was the director of the Los Alamos Laboratory that designed the actual bombs; the Army component of the project was designated the Manhattan District. Along the way, the project absorbed Tube Alloys; the Manhattan Project began modestly in 1939, but grew to employ more than 130,000 people and cost nearly US$2 billion. Over 90% of the cost was for building factories and to produce fissile material, with less than 10% for development and production of the weapons. Research and production took place at more than 30 sites across the United States, the United Kingdom, Canada. Two types of atomic bombs were developed concurrently during the war: a simple gun-type fission weapon and a more complex implosion-type nuclear weapon.
The Thin Man gun-type design proved impractical to use with plutonium, therefore a simpler gun-type called Little Boy was developed that used uranium-235, an isotope that makes up only 0.7 percent of natural uranium. Chemically identical to the most common isotope, uranium-238, with the same mass, it proved difficult to separate the two. Three methods were employed for uranium enrichment: electromagnetic and thermal. Most of this work was performed at the Clinton Engineer Works at Tennessee. In parallel with the work on uranium was an effort to produce plutonium. After the feasibility of the world's first artificial nuclear reactor was demonstrated in Chicago at the Metallurgical Laboratory, it designed the X-10 Graphite Reactor at Oak Ridge and the production reactors in Hanford, Washington, in which uranium was irradiated and transmuted into plutonium; the plutonium was chemically separated from the uranium, using the bismuth phosphate process. The Fat Man plutonium implosion-type weapon was developed in a concerted design and development effort by the Los Alamos Laboratory.
The project was charged with gathering intelligence on the German nuclear weapon project. Through Operation Alsos, Manhattan Project personnel served in Europe, sometimes behind enemy lines, where they gathered nuclear materials and documents, rounded up German scientists. Despite the Manhattan Project's tight security, Soviet atomic spies penetrated the program; the first nuclear device detonated was an implosion-type bomb at the Trinity test, conducted at New Mexico's Alamogordo Bombing and Gunnery Range on 16 July 1945. Little Boy and Fat Man bombs were used a month in the atomic bombings of Hiroshima and Nagasaki, respectively. In the immediate postwar years, the Manhattan Project conducted weapons testing at Bikini Atoll as part of Operation Crossroads, developed new weapons, promoted the development of the network of national laboratories, supported medical research into radiology and laid the foundations for the nuclear navy, it maintained control over American atomic weapons research and production until the formation of the United States Atomic Energy Commission in January 1947.
The discovery of nuclear fission by German chemists Otto Hahn and Fritz Strassmann in 1938, its theoretical explanation by Lise Meitner and Otto Frisch, made the development of an atomic bomb a theoretical possibility. There were fears that a German atomic bomb project would develop one first among scientists who were refugees from Nazi Germany and other fascist countries. In August 1939, Hungarian-born physicists Leó Szilárd and Eugene Wigner drafted the Einstein–Szilárd letter, which warned of the potential development of "extremely powerful bombs of a new type", it urged the United States to take steps to acquire stockpiles of uranium ore and accelerate the research of Enrico Fermi and others into nuclear chain reactions. They had it delivered to President Franklin D. Roosevelt. Roosevelt called on Lyman Briggs of the National Bureau of Standards to head the Advisory Committee on Uranium to investigate the issues raised by the letter. Briggs held a meeting on 21 October 1939, attended by Szilárd, Wigner and Edward Teller.
The committee reported back to Roosevelt in November that uranium "would provide a possible source of bombs with a destructiveness vastly greater than anything now known."The Advisory Committee on Uranium became the National Defense Research Committee Committee on Uranium when that organization was formed on 27 June 1940. Briggs proposed spending $167,000 on research into uranium the uranium-235 isotope, the discovered plutonium. On 28 June 1941, Roosevelt signed Executive Order 8807, which created the Office of Scientific Research and Development, with Vannevar Bush as its director; the office was empowered to engage in large engineering projects in addition to research. The NDRC Committee on Uranium became the S-1 Section of the OSRD. In Britain and Rudolf Peierls at the University of Birmingham had made a breakthrough investigating the critical mass of uranium-235 in June 1939, their calculations indicated that it was within an order of magnitude of 10 kilograms, small enough to be carried by a bomber of the day.
Their March 1940 Frisch–Peierls memorandum initiated the British atomic bomb project and its Maud Committee, which unanimously recommended pursuing the development of an atomic bomb
California is a state in the Pacific Region of the United States. With 39.6 million residents, California is the most populous U. S. the third-largest by area. The state capital is Sacramento; the Greater Los Angeles Area and the San Francisco Bay Area are the nation's second and fifth most populous urban regions, with 18.7 million and 9.7 million residents respectively. Los Angeles is California's most populous city, the country's second most populous, after New York City. California has the nation's most populous county, Los Angeles County, its largest county by area, San Bernardino County; the City and County of San Francisco is both the country's second-most densely populated major city after New York City and the fifth-most densely populated county, behind only four of the five New York City boroughs. California's $3.0 trillion economy is larger than that of any other state, larger than those of Texas and Florida combined, the largest sub-national economy in the world. If it were a country, California would be the 5th largest economy in the world, the 36th most populous as of 2017.
The Greater Los Angeles Area and the San Francisco Bay Area are the nation's second- and third-largest urban economies, after the New York metropolitan area. The San Francisco Bay Area PSA had the nation's highest GDP per capita in 2017 among large PSAs, is home to three of the world's ten largest companies by market capitalization and four of the world's ten richest people. California is considered a global trendsetter in popular culture, innovation and politics, it is considered the origin of the American film industry, the hippie counterculture, fast food, the Internet, the personal computer, among others. The San Francisco Bay Area and the Greater Los Angeles Area are seen as global centers of the technology and entertainment industries, respectively. California has a diverse economy: 58% of the state's economy is centered on finance, real estate services and professional, scientific and technical business services. Although it accounts for only 1.5% of the state's economy, California's agriculture industry has the highest output of any U.
S. state. California is bordered by Oregon to the north and Arizona to the east, the Mexican state of Baja California to the south; the state's diverse geography ranges from the Pacific Coast in the west to the Sierra Nevada mountain range in the east, from the redwood–Douglas fir forests in the northwest to the Mojave Desert in the southeast. The Central Valley, a major agricultural area, dominates the state's center. Although California is well-known for its warm Mediterranean climate, the large size of the state results in climates that vary from moist temperate rainforest in the north to arid desert in the interior, as well as snowy alpine in the mountains. Over time and wildfires have become more pervasive features. What is now California was first settled by various Native Californian tribes before being explored by a number of European expeditions during the 16th and 17th centuries; the Spanish Empire claimed it as part of Alta California in their New Spain colony. The area became a part of Mexico in 1821 following its successful war for independence but was ceded to the United States in 1848 after the Mexican–American War.
The western portion of Alta California was organized and admitted as the 31st state on September 9, 1850. The California Gold Rush starting in 1848 led to dramatic social and demographic changes, with large-scale emigration from the east and abroad with an accompanying economic boom; the word California referred to the Baja California Peninsula of Mexico. The name derived from the mythical island California in the fictional story of Queen Calafia, as recorded in a 1510 work The Adventures of Esplandián by Garci Rodríguez de Montalvo; this work was the fifth in a popular Spanish chivalric romance series that began with Amadis de Gaula. Queen Calafia's kingdom was said to be a remote land rich in gold and pearls, inhabited by beautiful black women who wore gold armor and lived like Amazons, as well as griffins and other strange beasts. In the fictional paradise, the ruler Queen Calafia fought alongside Muslims and her name may have been chosen to echo the title of a Muslim leader, the Caliph. It's possible.
Know ye that at the right hand of the Indies there is an island called California close to that part of the Terrestrial Paradise, inhabited by black women without a single man among them, they lived in the manner of Amazons. They were robust of body with great virtue; the island itself is one of the wildest in the world on account of the craggy rocks. Shortened forms of the state's name include CA, Cal. Calif. and US-CA. Settled by successive waves of arrivals during the last 10,000 years, California was one of the most culturally and linguistically diverse areas in pre-Columbian North America. Various estimates of the native population range from 100,000 to 300,000; the Indigenous peoples of California included more than 70 distinct groups of Native Americans, ranging from large, settled populations living on the coast to groups in the interior. California groups were diverse in their political organization with bands, villages, on the resource-rich coasts, large chiefdoms, such as the Chumash and Salinan.
Trade, intermarriage a
Royal Library of the Netherlands
The Royal Library of the Netherlands is based in The Hague and was founded in 1798. The mission of the Royal Library of the Netherlands, as presented on the library's web site, is to provide "access to the knowledge and culture of the past and the present by providing high-quality services for research and cultural experience"; the initiative to found a national library was proposed by representative Albert Jan Verbeek on August 17 1798. The collection would be based on the confiscated book collection of William V; the library was founded as the Nationale Bibliotheek on November 8 of the same year, after a committee of representatives had advised the creation of a national library on the same day. The National Library was only open to members of the Representative Body. King Louis Bonaparte gave the national library its name of the Royal Library in 1806. Napoleon Bonaparte transferred the Royal Library to The Hague as property, while allowing the Imperial Library in Paris to expropriate publications from the Royal Library.
In 1815 King William I of the Netherlands confirmed the name of'Royal Library' by royal resolution. It has been known as the National Library of the Netherlands since 1982, when it opened new quarters; the institution became independent of the state in 1996, although it is financed by the Department of Education and Science. In 2004, the National Library of the Netherlands contained 3,300,000 items, equivalent to 67 kilometers of bookshelves. Most items in the collection are books. There are pieces of "grey literature", where the author, publisher, or date may not be apparent but the document has cultural or intellectual significance; the collection contains the entire literature of the Netherlands, from medieval manuscripts to modern scientific publications. For a publication to be accepted, it must be from a registered Dutch publisher; the collection is accessible for members. Any person aged 16 years or older can become a member. One day passes are available. Requests for material take 30 minutes.
The KB hosts several open access websites, including the "Memory of the Netherlands". List of libraries in the Netherlands European Library Nederlandse Centrale Catalogus Books in the Netherlands Media related to Koninklijke Bibliotheek at Wikimedia Commons Official website
Claremont is a city on the eastern edge of Los Angeles County, United States, 30.3 miles east of downtown Los Angeles. It is in the Pomona Valley, at the foothills of the San Gabriel Mountains, has a population, as of the 2015 United States Census estimate, of 36,283 people. Claremont is known as the home of the Claremont Colleges and other educational institutions, for its tree-lined streets with numerous historic buildings. In July 2007, it was rated by CNN/Money magazine as the fifth best place to live in the United States, was the highest rated place in California on the list, it was named the best suburb in the West by Sunset Magazine in 2016, which described it as a "small city that blends worldly sophistication with small-town appeal." In 2018, Niche rated Claremont as the 17th best place to live in the Los Angeles area out of 658 communities it evaluated, based on crime, cost of living, job opportunities, local amenities. Due to its large number of trees and residents with doctoral degrees, as well as its proximity to the renowned Claremont Colleges, it is sometimes referred to as "The City of Trees and PhDs."The city is residential, with a significant portion of its commercial activity located in "The Village," a popular collection of street-front small stores, art galleries and restaurants adjacent to and west of the Claremont Colleges.
The Village was expanded in 2007, adding a controversial multi-use development that includes a cinema, a boutique hotel, retail space, a parking structure on the site of an old citrus packing plant west of Indian Hill Boulevard. Claremont has been a winner of the National Arbor Day Association's Tree City USA award for 22 consecutive years; when the city incorporated in 1907, local citizens started what has become the city's tree-planting tradition. Claremont is one of the few remaining places in North America with American Elm trees that have not been exposed to Dutch elm disease; the stately trees line Indian Hill Boulevard in the vicinity of the city's Memorial Park. The Claremont Institute, a conservative think tank, is located in nearby Upland, CA; the city hosts several large retirement communities, among them Pilgrim Place, the Claremont Manor and Mt. San Antonio Gardens; the citrus groves and open space which once dominated the northern portion of the city have been replaced by residential developments of large homes.
Construction of Stone Canyon Preserve, one of the final residential tract developments in the north of the city, commenced in 2003 as part of a complicated agreement between Pomona College and the City of Claremont which resulted in the creation of the 1,740-acre Wilderness Park. The foothill area includes the Padua Hills Theatre, a historic site constructed in 1930 and the Claraboya residential area. According to the United States Census Bureau, the city has a total area of 13.35 square miles, of which 13.3 square miles is land and 0.05 square miles is water. Claremont is located at the eastern end of Los Angeles County and borders the cities of Upland and Montclair in San Bernardino County, as well as the cities of Pomona and La Verne in Los Angeles County, it is geographically located in the San Gabriel Valley. Claremont is 24 miles east of Pasadena and 30 miles east of downtown Los Angeles. Claremont has a Mediterranean climate. In the summer months, temperatures can rise above 100 °F. In the autumn months, Claremont can receive gusty winds known as the "Santa Ana Winds", which can bring fire danger to nearby foothills.
In the winter, most of its annual rainfall occurs. Snow is rare but can be viewed in the nearby San Gabriel Mountains. In early summer, Claremont can receive overcast weather due to its strong onshore flow from the ocean known as "May Gray" or "June Gloom"; the 2010 United States Census reported that Claremont had a population of 34,926. The population density was 2,589.7 people per square mile. The racial makeup of Claremont was 24,666 White, 1,651 African American, 172 Native American, 4,564 Asian, 38 Pacific Islander, 2,015 from other races, 1,820 from two or more races. Hispanic or Latino of any race were 6,919 persons; the Census reported that 29,802 people lived in households, 4,926 lived in non-institutionalized group quarters, 198 were institutionalized. There were 11,608 households, out of which 3,576 had children under the age of 18 living in them, 6,305 were opposite-sex married couples living together, 1,223 had a female householder with no husband present, 397 had a male householder with no wife present.
There were 429 unmarried opposite-sex partnerships, 138 same-sex married couples or partnerships. 2,957 households were made up of individuals and 1,556 had someone living alone, 65 years of age or older. The average household size was 2.57. There were 7,925 families; the population was spread out with 6,459 people under the age of 18, 6,778 people aged 18 to 24, 6,940 people aged 25 to 44, 8,979 people aged 45 to 64, 5,770 people who were 65 years of age or older. The median age was 38.6 years. For every 100 females, there were 88.4 males. For every 100 females age 18 and over, there were 84.7 males. There were 12,156 housing units at an average density of 901.3 per square mile, of which 7,700 were owner-occupied, 3,908 were occupied by renters. The homeowner vacancy rate was 0.9%. 21
New York University
New York University is a private research university founded in New York City but now with campuses and locations throughout the world. Founded in 1831, NYU's historical campus is in New York City; as a global university, students can graduate from its degree-granting campuses in NYU Abu Dhabi and NYU Shanghai, as well as study at its 12 academic centers in Accra, Buenos Aires, London, Los Angeles, Paris, Sydney, Tel Aviv, Washington, D. C. For the class that matriculated in the fall of 2019, NYU received nearly 85,000 applications for its undergraduate programs. In 2018, NYU was ranked amongst the top 40 universities worldwide by the Academic Ranking of World Universities, Times Higher Education World University Rankings, U. S. News & World Report. Alumni include heads of state, eminent scientists and entrepreneurs, media figures, founders and CEOs of Fortune 500 companies, astronauts; as of March 2019, 37 Nobel Laureates, 8 Turing Award winners, 5 Fields Medalists, over 30 Academy Award winners, over 30 Pulitzer Prize winners, hundreds of members of the National Academies of Sciences and United States Congress have been affiliated as faculty or alumni.
Globally, NYU is ranked 7th by the Times Higher Education World University Rankings for producing alumni who are millionaires, 4th by Wealth-X for producing ultra high net-worth and billionaire alumni. Albert Gallatin, Secretary of Treasury under Thomas Jefferson and James Madison, declared his intention to establish "in this immense and fast-growing city... a system of rational and practical education fitting and graciously opened to all". A three-day-long "literary and scientific convention" held in City Hall in 1830 and attended by over 100 delegates debated the terms of a plan for a new university; these New Yorkers believed the city needed a university designed for young men who would be admitted based upon merit rather than birthright or social class. On April 18, 1831, an institution was established, with the support of a group of prominent New York City residents from the city's merchants and traders. Albert Gallatin was elected as the institution's first president. On April 21, 1831, the new institution received its charter and was incorporated as the University of the City of New York by the New York State Legislature.
The university has been popularly known as New York University since its inception and was renamed New York University in 1896. In 1832, NYU held its first classes in rented rooms of four-story Clinton Hall, situated near City Hall. In 1835, the School of Law, NYU's first professional school, was established. Although the impetus to found a new school was a reaction by evangelical Presbyterians to what they perceived as the Episcopalianism of Columbia College, NYU was created non-denominational, unlike many American colleges at the time. American Chemical Society was founded in 1876 at NYU, it became one of the nation's largest universities, with an enrollment of 9,300 in 1917. NYU had its Washington Square campus since its founding; the university purchased a campus at University Heights in the Bronx because of overcrowding on the old campus. NYU had a desire to follow New York City's development further uptown. NYU's move to the Bronx occurred in 1894, spearheaded by the efforts of Chancellor Henry Mitchell MacCracken.
The University Heights campus was far more spacious. As a result, most of the university's operations along with the undergraduate College of Arts and Science and School of Engineering were housed there. NYU's administrative operations were moved to the new campus, but the graduate schools of the university remained at Washington Square. In 1914, Washington Square College was founded as the downtown undergraduate college of NYU. In 1935, NYU opened the "Nassau College-Hofstra Memorial of New York University at Hempstead, Long Island"; this extension would become a independent Hofstra University. In 1950, NYU was elected to the Association of American Universities, a nonprofit organization of leading public and private research universities. In the late 1960s and early 1970s, financial crisis gripped the New York City government and the troubles spread to the city's institutions, including NYU. Feeling the pressures of imminent bankruptcy, NYU President James McNaughton Hester negotiated the sale of the University Heights campus to the City University of New York, which occurred in 1973.
In 1973, the New York University School of Engineering and Science merged into Polytechnic Institute of Brooklyn, which merged back into NYU in 2014 forming the present Tandon School of Engineering. After the sale of the Bronx campus, University College merged with Washington Square College. In the 1980s, under the leadership of President John Brademas, NYU launched a billion-dollar campaign, spent entirely on updating facilities; the campaign was set to complete in 15 years, but ended up being completed in 10. In 1991, L. Jay Oliva was inaugurated the 14th president of the university. Following his inauguration, he moved to form the League of World Universities, an international organization consisting of rectors and presidents from urban universities across six continents; the league and its 47 representatives gather every two years to discuss global issues in education. In 2003 President John Sexton launched a $2.5 billion campaign for funds to be spent on faculty and financial aid resources.
Under Sextons leadership, NYU began its radical transformation into a global university. In 2009, the university responded to a series of New York Times interviews that showed a pattern of labor abuses in its fledgling Abu Dhabi location, creating a statement of
Organic chemistry is a subdiscipline of chemistry that studies the structure and reactions of organic compounds, which contain carbon in covalent bonding. Study of structure determines their chemical formula. Study of properties includes physical and chemical properties, evaluation of chemical reactivity to understand their behavior; the study of organic reactions includes the chemical synthesis of natural products and polymers, study of individual organic molecules in the laboratory and via theoretical study. The range of chemicals studied in organic chemistry includes hydrocarbons as well as compounds based on carbon, but containing other elements oxygen, sulfur and the halogens. Organometallic chemistry is the study of compounds containing carbon–metal bonds. In addition, contemporary research focuses on organic chemistry involving other organometallics including the lanthanides, but the transition metals zinc, palladium, cobalt and chromium. Organic compounds constitute the majority of known chemicals.
The bonding patterns of carbon, with its valence of four—formal single and triple bonds, plus structures with delocalized electrons—make the array of organic compounds structurally diverse, their range of applications enormous. They form the basis of, or are constituents of, many commercial products including pharmaceuticals; the study of organic chemistry overlaps organometallic chemistry and biochemistry, but with medicinal chemistry, polymer chemistry, materials science. Before the nineteenth century, chemists believed that compounds obtained from living organisms were endowed with a vital force that distinguished them from inorganic compounds. According to the concept of vitalism, organic matter was endowed with a "vital force". During the first half of the nineteenth century, some of the first systematic studies of organic compounds were reported. Around 1816 Michel Chevreul started a study of soaps made from various alkalis, he separated the different acids. Since these were all individual compounds, he demonstrated that it was possible to make a chemical change in various fats, producing new compounds, without "vital force".
In 1828 Friedrich Wöhler produced the organic chemical urea, a constituent of urine, from inorganic starting materials, in what is now called the Wöhler synthesis. Although Wöhler himself was cautious about claiming he had disproved vitalism, this was the first time a substance thought to be organic was synthesized in the laboratory without biological starting materials; the event is now accepted as indeed disproving the doctrine of vitalism. In 1856 William Henry Perkin, while trying to manufacture quinine accidentally produced the organic dye now known as Perkin's mauve, his discovery, made known through its financial success increased interest in organic chemistry. A crucial breakthrough for organic chemistry was the concept of chemical structure, developed independently in 1858 by both Friedrich August Kekulé and Archibald Scott Couper. Both researchers suggested that tetravalent carbon atoms could link to each other to form a carbon lattice, that the detailed patterns of atomic bonding could be discerned by skillful interpretations of appropriate chemical reactions.
The era of the pharmaceutical industry began in the last decade of the 19th century when the manufacturing of acetylsalicylic acid—more referred to as aspirin—in Germany was started by Bayer. By 1910 Paul Ehrlich and his laboratory group began developing arsenic-based arsphenamine, as the first effective medicinal treatment of syphilis, thereby initiated the medical practice of chemotherapy. Ehrlich popularized the concepts of "magic bullet" drugs and of systematically improving drug therapies, his laboratory made decisive contributions to developing antiserum for diphtheria and standardizing therapeutic serums. Early examples of organic reactions and applications were found because of a combination of luck and preparation for unexpected observations; the latter half of the 19th century however witnessed systematic studies of organic compounds. The development of synthetic indigo is illustrative; the production of indigo from plant sources dropped from 19,000 tons in 1897 to 1,000 tons by 1914 thanks to the synthetic methods developed by Adolf von Baeyer.
In 2002, 17,000 tons of synthetic indigo were produced from petrochemicals. In the early part of the 20th century and enzymes were shown to be large organic molecules, petroleum was shown to be of biological origin; the multiple-step synthesis of complex organic compounds is called total synthesis. Total synthesis of complex natural compounds increased in complexity to terpineol. For example, cholesterol-related compounds have opened ways to synthesize complex human hormones and their modified derivatives. Since the start of the 20th century, complexity of total syntheses has been increased to include molecules of high complexity such as lysergic acid and vitamin B12; the discovery of petroleum and the development of the petrochemical industry spurred the development of organic chemistry. Converting individual petroleum compounds into different types of compounds by various chemical processes led to organic reactions enabling a broad range of