Malta Independence Fiftieth Anniversary Medal

The Malta Independence Fiftieth Anniversary Medal is a national commemorative medal of the Republic of Malta. The medal is awarded by the President of Malta to recognize contributions to the development and well-being of Malta as a nation and a member of the international community of nations since the State of Malta gained independence in 1964; the medal, which may be awarded posthumously, has been awarded to former Presidents, Prime Ministers, other notable Maltese politicians. The Malta Independence Fiftieth Anniversary Medal is circular, 36 mm wide, made of cupro-nickel; the obverse of the medal depicts the Coat of arms of Malta, with the year 2014 at its base. The reverse bears a depiction of the Coat of arms of Malta of 1964 in the center, circumscribed in relief by ĦAMSIN ANNIVERSARJU MILLINDIPENDENZA separated by a Maltese Cross from the inscription MALTA 1964 at the base; the Medal's suspension ribbon is 32 mm divided into equal halves of white and red. The medal attached to the ribbon by a bar-type suspension.

On the bar is a design, of an olive branch and palm frond joined at the middle. Recipients' names are engraved on the rim of the medal. Dr George Abela Dr Edward Fenech Adami Agatha Barbara † Dr Karmenu Mifsud Bonnici Dr Ugo Mifsud Bonnici Dr Anton Buttigieg † Professor Guido de Marco † Dr Lawrence Gonzi Sir Anthony MamoDom MintoffJoseph Muscat Dr Giorgio Borg Olivier † Dr Alfred Sant Dr Ċensu TabonePaul Xuereb ††=posthumous award

Receptor for activated C kinase 1

Receptor for activated C kinase 1 known as guanine nucleotide-binding protein subunit beta-2-like 1, is a 35 kDa protein that in humans is encoded by the RACK1 gene. RACK1 was isolated and identified as an intracellular protein receptor for protein kinase C, noting the significant homology to the beta subunit of heterotrimeric G proteins. Studies established RACK1, its yeast homolog Asc1, as a core ribosomal protein of the eukaryotic small ribosomal subunit. Much of the function of Asc1/RACK1 appears to result from its position on the'head' of the 40S ribosomal subunit. Asc1/RACK1 participates in several aspects of eukaryotic translation and ribosome quality control, including IRES-mediated translation, non-stop decay, non-functional 18S ribosomal RNA decay, frameshifting. RACK1 is positioned at the solvent-exposed surface of the 40S ribosomal subunit, where it is held in place through contacts with both the 18S rRNA and other ribosomal proteins, including uS3, uS9, eS17. Additionally, RACK1 has been shown to interact with: Eukaryotic small ribosomal subunit Protein kinase C Heterotrimeric G protein