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Dysdiadochokinesia is the medical term for an impaired ability to perform rapid, alternating movements. Complete inability is called adiadochokinesia; the term is from Greek δυς dys "bad", διάδοχος diadochos "succeeding", κίνησις kinesis "movement". Abnormalities in diadochokinesia can be seen in speech; the deficits become visible in the rate of alternation, the completeness of the sequence, in the variation in amplitude involving both motor coordination and sequencing. Average rate can be used as a measure of performance. Dysdiadochokinesia is demonstrated clinically by asking the patient to tap the palm of one hand with the fingers of the other rapidly turn over the fingers and tap the palm with the back of them, repeatedly; this movement is known as a pronation/supination test of the upper extremity. A simpler method using this same concept is to ask the patient to demonstrate the movement of trying a doorknob or screwing in a light bulb; when testing for this condition in legs, ask the patient to tap your hand as as possible with the ball of each foot in turn.

Movements tend to be awkward. The feet perform less well than the hands; when testing for dysdiadochokinesia with speech the patient is asked to repeat syllables such as /pə/, /tə/, /kə/. Dysdiadochokinesia is a feature of cerebellar ataxia and may be the result of lesions to either the cerebellar hemispheres or the frontal lobe, it can be a combination of both, it is thought to be caused by the inability to switch on and switch off antagonising muscle groups in a coordinated fashion due to hypotonia, secondary to the central lesion. Dysdiadochokinesia is seen in Friedreich's ataxia and multiple sclerosis, as a cerebellar symptom, it is a feature of ataxic dysarthria. Dysdiadochokinesia presents in motor speech disorders, therefore testing for dysdiadochokinesia can be used for a differential diagnosis. Dysdiadochokinesia has been linked to a mutation in SLC18A2, which encodes vesicular monoamine transporter 2

Cotton factor

In the antebellum South, most cotton planters relied on cotton factors to sell their crops for them. This factor was located in an urban center of commerce, such as Charleston, New Orleans, or Savannah, where they could most efficiently tend to business matters for their rural clients. Prior to the American Civil War, the states of Alabama, Georgia and Mississippi were producing more than half of the world's cotton, but Arkansas and Texas produced large amounts also. At the same time, the port of New Orleans exported the most cotton, followed by the port of Mobile. Cotton factors frequently purchased goods for their clients, handled shipment of those goods to the clients, among other services; as one source notes, The factor was a versatile man of business in an agrarian society who performed many different services for the planter in addition to selling his crops. He purchased or sold slaves for his client, arranged for the hiring of slaves or the placing of the planter's children in distant schools, gave advice concerning the condition of the market or the advisability of selling or withholding his crop, bought for his client a large proportion of the plantation supplies.

Not all factors in the antebellum South were cotton factors. In 1858, for example, New Orleans boasted sixty-three sugar and molasses factors. Louisiana produced large amounts of sugar cane, but it had an greater number of cotton factors. Factor Mobile Cotton Exchange New Orleans Cotton Exchange Edmund Richardson

Marino Salas

Marino Salas Ortega is a former Major League Baseball relief pitcher, now playing for the Athletics Bologna in the Italian Serie A Federale. Salas was claimed off waivers from the Baltimore Orioles by the Milwaukee Brewers on February 1, 2007, he played for Milwaukee's Double-A and Triple-A clubs, the Huntsville Stars and the Nashville Sounds. On December 7, 2007, Salas was traded to the Pittsburgh Pirates along with Kevin Roberts for Salomón Torres, he became a free agent at the end of the 2008 season. He played in Italy for BSC Rovigo, as a starting pitcher. On August 1, 2015, he pitched a no-hitter against Grosseto at the Jannella Stadium, in a playoff game. Career statistics and player information from MLB, or Baseball-Reference, or Baseball-Reference "Salas Traded to Pittsburgh." Huntsville Stars. 7 December 2007

St Muredach's Cathedral, Ballina

St Muredach's Cathedral is the cathedral church of the Roman Catholic Diocese of Killala in Ireland. It is located on the east bank of the River Moy in County Mayo, it is the parish church of the parish of Kilmoremoy. It is a detached six-bay double-height building on a cruciform plan comprising a four-bay double-height nave which opens into single-bay double-height transepts all centred on a single-bay double-height chancel; the cathedral's construction was initiated by Bishop John MacHale who served as the Bishop of Killala from 1825-1834 and the completion of the cathedral in 1834 coincided with his translation to the Archdiocese of Tuam. The spire was completed in 1855 to the designs of the celebrated architect James Joseph McCarthy and further embellishment continued throughout the nineteenth century; the cathedral is situated in the townland of Abbeyhalfquarter. When built, it was in County Sligo, but since the 1898 revisions of county boundaries, it has been in County Mayo. Richard Hoare Francis Beolane John Finan John Lyons John McHale John Lyons P.

A. Lyons Patrick McHale Bart Costello Hugh Conway Patrick Malone Dominick Madden Michael Conway J. Gilvarry P. J. Nolan P. Irwin J. Timlin P. Conway H. Hewson J. J. O'Keane P. McNulty D. O'Donoghue A. Finnerty J. Mullen A. McHale M. Gallagher J. Naughton B. Quinn T. L. Beirne M. Tully W. Greaney D. O'Connor M. J. Feeney P. Maloney J. Heverin T. McDonnell G. Moore P. O' Brien M. Flynn M. Flynn Brendan Hoban, a founder member of the Association of Catholic Priests Gerard O'Hora Aidan O'Boyle (2019-

The Lives and Times of Jerry Cornelius

The Lives and Times of Jerry Cornelius is a collection of short stories by British fantasy and science fiction writer Michael Moorcock. It is part of his long-running Jerry Cornelius series; the book was published by Allison & Busby in 1976 and collects stories published between 1969 and 1974. A edition was published in 2003 by Four Walls Eight Windows, in which four stories from the original edition are replaced. "The Peking Junction" "The Delhi Division" "The Tank Trapeze" "The Nature of the Catastrophe" "The Swastika Set-Up" "The Sunset Perspective" "Sea Wolves" "Voortrekker" "Dead Singers" "The Longford Cup" "The Entropy Circuit" Introduction "The Peking Junction" "The Delhi Division" "The Tank Trapeze" "The Swastika Set-Up" "The Sunset Perspective" "Sea Wolves" "Voortrekker" "The Spencer Inheritance" "The Camus Connection" "Cheering for the Rockets" "Firing the Cathedral" Brown, Charles N.. "The Locus Index to Science Fiction". Retrieved 2007-12-13. Contento, William G. "Index to Science Fiction Anthologies and Collections, Combined Edition".

Retrieved 2007-12-13. The Lives and Times of Jerry Cornelius title listing at the Internet Speculative Fiction Database

Volleyball at the 2012 Summer Olympics – Men's tournament

The men's tournament in volleyball at the 2012 Summer Olympics was the 13th edition of the event at the Summer Olympics, organised by the world's governing body, the FIVB, in conjunction with the IOC. It was held in London, United Kingdom from 29 July to 12 August 2012. Russia won the gold medal in a 3–2 victory against Brazil. Teams were seeded following the Serpentine system according to their FIVB World Ranking as of 4 January 2012. FIVB reserved the right to seed the hosts as head of pool A regardless of the World Ranking. Rankings are shown in brackets except the hosts. Match points Number of matches won Sets ratio Points ratio Result of the last match between the tied teamsMatch won 3–0 or 3–1: 3 match points for the winner, 0 match points for the loser Match won 3–2: 2 match points for the winner, 1 match point for the loser All times are British Summer Time; the top four teams in each pool qualified for the quarterfinals. All times are British Summer Time; the first ranked teams of both pools played against the fourth ranked teams of the other pool.

The second ranked teams faced the second or third ranked teams of the other pool, determined by drawing of lots. The drawing of lots was held after the last match in the preliminary round. Volleyball at the 2012 Summer Olympics – Women's tournament Official website Final Standing Awards Statistics Results at Results at