Epi-isozizaene synthase

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Epi-isozizaene synthase
Identifiers
EC number 4.2.3.37
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Epi-isozizaene synthase (EC 4.2.3.37, SCO5222 protein) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((+)-epi-isozizaene-forming).[1][2] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (+)-epi-isozizaene + diphosphate

This enzyme requires Mg2+ for activity.

References[edit]

  1. ^ Lin, X.; Hopson, R.; Cane, D.E. (2006). "Genome mining in Streptomyces coelicolor: molecular cloning and characterization of a new sesquiterpene synthase". J. Am. Chem. Soc. 128 (18): 6022–6023. doi:10.1021/ja061292s. PMC 2533732Freely accessible. PMID 16669656. 
  2. ^ Zhao, B.; Lin, X.; Lei, L.; Lamb, D.C.; Kelly, S.L.; Waterman, M.R.; Cane, D.E. (2008). "Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor A3(2)". J. Biol. Chem. 283: 8183–8189. doi:10.1074/jbc.M710421200. PMC 2276382Freely accessible. PMID 18234666. 

External links[edit]