Exposition Park in the south region of Los Angeles, California, is a 160 acres urban park. Established in 1872 as an agricultural fairground, it includes the Los Angeles Memorial Coliseum, the Banc of California Stadium, the California Science Center, the Natural History Museum of Los Angeles County, the California African American Museum; the Lucas Museum of Narrative Art is under construction. Bounded by Exposition Boulevard to the north, South Figueroa Street to the east, Martin Luther King Jr. Boulevard to the south and Menlo Avenue to the west, it is directly south of the main campus of the University of Southern California; the park is public open space, managed by the California Natural Resources Agency. Exposition Park houses the following: LA84 Foundation/John C. Argue Swim Stadium Banc of California Stadium Home of Los Angeles FC Lucas Museum of Narrative Art Los Angeles Memorial Coliseum Home of USC Trojans football Natural History Museum of Los Angeles County California Science Center IMAX Theatre at California Science Center Space Shuttle Endeavour Exposition Park Rose Garden California African American Museum Concrete hand and footprints signed by Ed Begley Jr. of St. Elsewhere and other actors from medical TV shows such as Ben Casey EXPO Center and the Soboroff Sports Field Science Center School and Amgen Center for Science Learning The cultural facilities mentioned above are operated by both the state and Los Angeles County.
Los Angeles Memorial Sports Arena The 160-acre site served as an agricultural fairground from 1872 to 1910. In 1880, John Edward, Ozro W. Childs, former California Governor John G. Downey persuaded the State of California to purchase 160 acres in Los Angeles to foster agriculture in the Southland. Farmers sold their harvest and arces on the grounds, while horses and camels competed on a racetrack where a rose garden now sits and blooms. In 1909, a group of civic-minded individuals led by former Pasadena Mayor Horace Dobbins set about reforming the park, removing the racetrack and other activities and replacing them with gardens and museums. At the 2028 Summer Olympics, the Coliseum will host Athletics as well as the main closing ceremony; the Banc of California Stadium will be one of the soccer venues. Along the northern edge of the park, the Metro Expo Line light rail line serves the park with its Expo Park/USC Station. On the northeast, the Metro Silver Line bus rapid transit serves Exposition Park & USC at its 37th Street/USC Station on the Harbor Transitway.
The Silver Line station is located on the freeway median level of the 1-110 freeway. Exposition Park is a community located in South Los Angeles with varying amounts of crime. According to the L. A. Department of City Planning, the population in 2008 was about 33,400 people. Ethnicities in this neighborhood are African American and Latinos. About 56 % are 38 % African American; the remaining percentages are 1.6 % Asian and 2 % other. The average age in Exposition Park is around 26 years old; the University of Southern California is located in Exposition Park. South of the campus is an assortment of museums, including the California African American Museum, the California Science Center, Exposition Park Rose Garden, the Los Angeles Memorial Coliseum, the Natural History Museum of Los Angeles County. All of this corresponds to the crime that occurs near and in Exposition Park. In the last several decades the crime rate has decreased tremendously. In 1995 reported violent crimes in Los Angeles County were 1,437 and in 2016 the rate was 553 total violent crimes.
Exposition Park was rated number 16 for the most violent crimes in Los Angeles neighborhoods out of 197 in the year 2018. The week of November 22 through 28, 2018, there were 5 violent crimes, 23 property crimes, about 840 crimes total by means of 10,000 people in Exposition Park. In 2017 there was a massive gang arrest in Exposition Park. Arrested for federal charges, around 44 gang suspects were retained for murder and racketeering, which means false or crooked business dealings. California State and Consumer Services Agency List of parks in Los Angeles Official website — Exposition Park. University Park Family — an online newspaper and social network focused on the neighborhoods around USC and Exposition Park, the surrounding areas. Leimert Park Beat — a collaborative online community focused nearby Leimert Park: "The Soul of Los Angeles and the African American cultural center of the city"
Jan Žižka z Trocnova a Kalicha was a Czech general, a contemporary and follower of Jan Hus, Hussite military leader, also a Radical Hussite who led the Taborites. Žižka is held to be one of the most renowned military leaders by many historians and today he is considered a Czech national hero. He was born in the small village of Trocnov in the Kingdom of Bohemia into an aristocratic family, he was nicknamed "One-eyed Žižka". From his youth, he was attached to the royal court and held the office of Chamberlain to Queen Sofia of Bavaria, he fought in the Battle of Grunwald. He played a prominent role in the civil wars in Bohemia during the reign of Wenceslas IV. Žižka's tactics were innovative. In addition to training and equipping his army according to their abilities, he used armored wagons fitted with small cannons and muskets, anticipating the tank of five hundred years later, he knew how to exploit geographic features to the full, maintain discipline in his armies. In the Battle of Kutná Hora he defeated the army of the Holy Roman Hungary.
The effectiveness of field artillery against the royal cavalry in the battle turned field artillery into a firm part of Hussite armies. Žižka is considered to be among the greatest military innovators of all time. His accomplishments in this regard are unique and noteworthy as he had to train peasants to face trained and armored opponents who severely outnumbered his own troops, for this, some have considered him to be the greatest general in history. A monument was erected on the Vítkov Hill in Prague to honor Jan Žižka and his victory on this hill in 1420, it is the third largest bronze equestrian statue in the world. Žižka was on the winning side of the Battle of Grunwald called the 1st Battle of Tannenberg, one of the largest battles in Medieval Europe. It was fought on July 1410, during the Polish -- Lithuanian -- Teutonic War; the alliance of the Kingdom of Poland and the Grand Duchy of Lithuania, led by King of Poland Władysław Jagiełło and Grand Duke Vytautas, decisively defeated the Teutonic Knights, led by Grand Master Ulrich von Jungingen.
Most of the Teutonic Knights' leadership were taken prisoner. The Knights never recovered their former power and the financial burden of war reparations caused internal conflicts and an economic downturn in their lands; the battle shifted the balance of power in Eastern Europe. Žižka was the military leader of the Hussites in the Hussite Wars. The Hussites were a proto-Protestant, Christian movement following the teachings of Czech priest, philosopher and master at Charles University in Prague, Jan Hus. On November 13, 1419 a temporary armistice was concluded between the partisans of King Sigismund, the last Emperor of the House of Luxemburg and the citizens of Prague. Žižka disapproved of this compromise and left Prague for Plzeň, one of the richest cities of the kingdom with his followers, but soon left that city. On March 25, 1420 he defeated the partisans of Sigismund at Sudoměř, the first pitched battle of the Hussite wars, he arrived at Tábor, the then-recently established stronghold of the Hussite movement.
The ecclesiastical organization of Tabor had a somewhat puritanical character with a strict military discipline being instituted though the government was established on a democratic basis. Žižka took a large part in the organization of the new military community and became one of the four captains of the people who were at its head. Žižka helped develop tactics of using wagon forts, called vozová hradba in Czech or Wagenburg by the Germans, as mobile fortifications. When the Hussite army faced a numerically superior opponent they prepared carts for the battle by forming them into squares or circles; the carts were joined wheel to wheel by chains and positioned aslant, with their corners attached to each other, so that horses could be harnessed to them if necessary. In front of this wall of carts a ditch was dug by camp followers; the crew of each cart consisted of 16–22 soldiers: 4–8 crossbowmen, 2 handgunners, 6–8 soldiers equipped with pikes or flails, 2 shield carriers and 2 drivers. The Hussites' battle consisted of two stages, the first defensive, the second an offensive counterattack.
In the first stage the army placed the carts near the enemy army and by means of artillery fire provoked the enemy into battle. The artillery would inflict heavy casualties at close range. In order to avoid more losses, the enemy knights attacked; the infantry hidden behind the carts used firearms and crossbows to ward off the attack, weakening the enemy. The shooters aimed first at the horses. Many of the knights died as they fell; as soon as the enemy's morale was lowered, the second stage, an offensive counterattack, began. The infantry and the cavalry burst out from behind the carts striking violently at the enemy from the flanks. While fighting on the flanks and being shelled from the carts the enemy was not able to put up much resistance, they were forced to withdraw, leaving behind dismounted knights in heavy armor who were unable to escape the battlefield. The enemy armies suffered heavy losses and the Hussites soon had the reputation of not taking captives; the Hussite wars marked the earliest successful use of pistols on the battlefield and Žižka was an innovator in the use of gunpowder.
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C-C chemokine receptor type 4 is a protein that in humans is encoded by the CCR4 gene. CCR4 has recently been designated CD194; the protein encoded by this gene belongs to the G protein-coupled receptor family. It is a receptor for the following CC chemokines: CCL2 CCL4 CCL5 CCL17 CCL22 Chemokines are a group of small structurally related proteins that regulate cell trafficking of various types of leukocytes; the chemokines play fundamental roles in the development and function of the immune system, they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. CCR4 is expressed on leukemic cells in cutaneous T-cell lymphoma. Mogamulizumab is a humanised monoclonal antibody targeted at CCR4 and is an investigational drug for CTCL. Human CCR4 genome location and CCR4 gene details page in the UCSC Genome Browser. CCR4+receptor at the US National Library of Medicine Medical Subject Headings "Chemokine Receptors: CCR4". IUPHAR Database of Receptors and Ion Channels.
International Union of Basic and Clinical Pharmacology. This article incorporates text from the United States National Library of Medicine, in the public domain