Georgetown is the third oldest city in the U.S. state of South Carolina and the county seat of Georgetown County, in the Lowcountry. As of the 2010 census it had a population of 9,163. Located on Winyah Bay at the confluence of the Black, Great Pee Dee, Waccamaw, and Sampit rivers, Georgetown is the second largest seaport in South Carolina, handling over 960,000 tons of materials a year, while Charleston is the largest.

South Carolina is a state in the coastal Southeastern region of the United States. It borders North Carolina to the north, the Atlantic Ocean to the southeast, and Georgia to the southwest across the Savannah River. Along with North Carolina, it makes up the Carolinas region of the East Coast. South Carolina is the 40th-largest and 23rd-most populous U.S. state with a recorded population of 5,118,425 according to the 2020 census. In 2019, its GDP was $213.45 billion. South Carolina is composed of 46 counties. The capital is Columbia with a population of 136,632 in 2020; while its most populous city is Charleston with a 2020 population of 150,227. The Greenville-Spartanburg-Anderson, SC Combined Statistical Area is the most populous combined metropolitan area in the state, with an estimated 2023 population of 1,590,636.