HMS Express was an E-class minelaying destroyer built for the Royal Navy in the early 1930s. Although assigned to the Home Fleet upon completion, the ship was attached to the Mediterranean Fleet in 1935–36 during the Abyssinia Crisis. During the Spanish Civil War of 1936–1939, she spent considerable time in Spanish waters, enforcing the arms blockade imposed by Britain and France on both sides of the conflict.

The E and F-class destroyers were a group of 18 destroyers built for the Royal Navy during the 1930s. The ships were initially assigned to the Home Fleet, although they reinforced the Mediterranean Fleet during the Italian invasion of Abyssinia of 1935–36 and enforced the Non-Intervention Agreement during the Spanish Civil War of 1936–1939. After the beginning of the Second World War in August 1939, the E-class ships were mostly assigned to escort duties under the Western Approaches Command, while the Fs were assigned to escort the ships of the Home Fleet. Between them they sank four German submarines through March 1940 while losing only one ship to a submarine.