HMS Prince William was a 64-gun third-rate ship of the line of the Royal Navy. She had previously been Guipuzcoano, an armed 64-gun ship of the Spanish (Basque) mercantile Guipuzcoan Company of Caracas. She was also known by the religious name of Nuestra Señora de la Asunción.

The action of 8 January 1780 was a naval encounter off Cape Finisterre between a British Royal Naval fleet under Admiral Sir George Rodney, and a fleet of Spanish merchants sailing in convoy with seven warships of the Caracas Company, under the command of Commodore Don Juan Augustin de Yardi. During the action the entire Spanish convoy was captured. Rodney's fleet was en route to relieve Gibraltar, and this action took place several days before Rodney's engagement and defeat of a Spanish fleet at the Battle of Cape St. Vincent.