Hanover High School is the only public high school in the Dresden School District, and is located in Hanover, New Hampshire, United States. In 1963 it became the first interstate high school in the country as part of a bill that was the last signed into action by John F. Kennedy. Today it accepts students from several communities in New Hampshire and Vermont. Enrollment is approximately 786 students, the majority of whom come from the towns of Hanover and Norwich, Vermont. 11% of the student body attends on a tuition basis from towns such as Cornish and Lyme, New Hampshire, and Strafford and Hartland, Vermont. The school employs 79 full-time faculty members.

Hanover is a town located along the Connecticut River in Grafton County, New Hampshire, United States. As of the 2020 census, its population was 11,870. The town is home to the Ivy League university Dartmouth College, the U.S. Army Corps of Engineers Cold Regions Research and Engineering Laboratory, and Hanover High School. The Appalachian Trail crosses the town, connecting with a number of trails and nature preserves.