Humboldt is a city in the province of Saskatchewan, Canada. It is located 113 km east of Saskatoon at the junction of Highway 5 and Highway 20. The city is surrounded by the Rural Municipality of Humboldt No. 370.

Highway 5 is a major highway in the Canadian province of Saskatchewan. It begins in downtown Saskatoon and runs eastward to the Manitoba border near Togo, where it becomes Provincial Road 363. The highway is approximately 393 kilometres (244 mi) long. Between the early 1900s (decade) and 1976, Provincial Highway 5 was a trans-provincial highway travelling approximately 630 kilometres (390 mi) in length. At this time it started at the Alberta border in Lloydminster and traveled east to the Manitoba border.