INPP4B

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INPP4B
Identifiers
AliasesINPP4B, inositol polyphosphate-4-phosphatase type II B
External IDsMGI: 2158925 HomoloGene: 20832 GeneCards: INPP4B
Gene location (Human)
Chromosome 4 (human)
Chr.Chromosome 4 (human)[1]
Chromosome 4 (human)
Genomic location for INPP4B
Genomic location for INPP4B
Band4q31.21Start142,023,160 bp[1]
End142,847,432 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001101669
NM_003866
NM_001331040

NM_001024617
NM_001297591
NM_001297593
NM_001297596

RefSeq (protein)

NP_001095139
NP_001317969
NP_003857

NP_001019788
NP_001284520
NP_001284522
NP_001284525

Location (UCSC)Chr 4: 142.02 – 142.85 MbChr 8: 81.34 – 82.13 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Inositol polyphosphate-4-phosphatase, type II, 105kDa is a protein that in humans is encoded by the INPP4B gene.[5]

INPP4B encodes the inositol polyphosphate 4-phosphatase type II, a dual specificity phosphatase. INPP4B is involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme.[5]

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.