In Enemy Hands is a 2004 American submarine film directed by Tony Giglio and starring William H. Macy, Til Schweiger, Thomas Kretschmann, Scott Caan and Lauren Holly. The film follows an American submarine crew getting captured by a German submarine crew and taken prisoner aboard their U-boat.

The submarine film is a subgenre of war film in which the majority of the plot revolves around a submarine below the ocean's surface. Films of this subgenre typically focus on a small but determined crew of submariners battling against enemy submarines or submarine-hunter ships, or against other problems ranging from disputes amongst the crew, threats of mutiny, life-threatening mechanical breakdowns, or the daily difficulties of living on a submarine.