Interstate 295 (I-295) is a highway which runs eastward and northward bypass of the cities of Richmond and Petersburg in the US state of Virginia. The southern terminus is an interchange with I-95 southeast of Petersburg. I-295 then has an interchange with I-64 east of Richmond, crosses I-95 north of Richmond, and continues westward to its other terminus at a second interchange with I-64.

A bypass is a road or highway that avoids or "bypasses" a built-up area, town, or village, to let through traffic flow without interference from local traffic, to reduce congestion in the built-up area, and to improve road safety. A bypass specifically designated for trucks may be called a truck route.