Jackson County is a county located in the U.S. state of Florida, on its northwestern border with Alabama. As of the 2020 census, the population was 47,319. Its county seat is Marianna.

Marianna is a city in and the county seat of Jackson County, Florida, United States, and it is home to Chipola College. The official nickname of Marianna is "The City of Southern Charm". The population was 6,245 at the 2020 census.