From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
IUPAC name
Other names
3D model (JSmol)
Molar mass 266.34 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Juncusol is a 9,10-dihydrophrenathrene found in Juncus species such as J. acutus,[1] J. effusus[2][3] or J. roemerianus.[4][5]

It can also be synthesized.[6][7][8]

This compound shows antimicrobial activity against Bacillus subtilis and Staphylococcus aureus.[4] It also has a toxic effect on estuarine fish and shrimp.[9]


  1. ^ Behery, Fathi Abdelmohsen Abdelhalim; Naeem, Zain Elabdin Metwally; Maatooq, Galal Taha; Amer, Mohamed Mahmoud Abdelfattah; Wen, Zhi-Hong; Sheu, Jyh-Horng; Ahmed, Atallah Fouad (2007). "Phenanthrenoids from Juncus acutus L., New Natural Lipopolysaccharide-Inducible Nitric Oxide Synthase Inhibitors". Chemical & Pharmaceutical Bulletin. 55 (8): 1264. doi:10.1248/cpb.55.1264. 
  2. ^ Bhattacharyya (1980). "Structure of effusol: A new phenolic constituent fromJuncus effusus". Experientia. 36: 27. doi:10.1007/bf02003949. 
  3. ^ Shima (1991). "Phenanthrene derivatives from the medullae of Juncus effusus". Phytochemistry. 30: 3149. doi:10.1016/s0031-9422(00)98276-1. 
  4. ^ a b Chapatwala, Kirit D.; de la Cruz, Armando A.; Miles, D.Howard (1981). "Antimicrobial activity of juncusol, a novel 9-10-dihydrophenanthrene from the marsh plant". Life Sciences. 29 (19): 1997. doi:10.1016/0024-3205(81)90609-3. PMID 6796796. 
  5. ^ Miles, D. H.; Bhattacharyya, J; Mody, N. V.; Atwood, J. L.; Black, S; Hedin, P. A. (1977). "The structure of juncusol. A novel cytotoxic dihydrophenanthrene from the Estuarine marsh plant Juncus roemerianus". Journal of the American Chemical Society. 99 (2): 618–20. doi:10.1021/ja00444a056. PMID 830696. 
  6. ^ McDonald, Edward; Martin, Roger T. (1978). "Total synthesis of juncusol". Tetrahedron Letters. 19 (47): 4723. doi:10.1016/S0040-4039(01)85715-4. 
  7. ^ Boger, Dale L.; Mullican, Michael D. (1984). "Regiospecific total synthesis of juncusol". The Journal of Organic Chemistry. 49 (21): 4045. doi:10.1021/jo00195a034. 
  8. ^ Jacobi, Peter A.; Zheng, Wanjun (1991). "A novel synthesis of juncusol". Tetrahedron Letters. 32 (10): 1279. doi:10.1016/S0040-4039(00)79645-6. 
  9. ^ de la Cruz, A. A.; Miles, D. H.; Chapatwala, K. D. (1982). "Toxic effects of juncusol, a marsh plant phenolic extract, on estuarine fish and shrimp". Life Sciences. 30 (21): 1805–10. doi:10.1016/0024-3205(82)90317-4. PMID 7098770. 

External links[edit]