KStars is a licensed planetarium program using the KDE Platform. It is available for Linux, BSD, MacOS, Microsoft Windows. A light version of KStars is available for Android devices, it provides an accurate graphical representation of the night sky, from any location on Earth, at any date and time. The display includes up to 100 million stars, 13,000 deep sky objects, constellations from different cultures, all 8 planets, the Sun and Moon, thousands of comets, asteroids and supernovae, it has features to appeal to users of all levels, from informative hypertext articles about astronomy, to robust control of telescopes and CCD cameras, logging of observations of specific objects. KStars supports adjustable simulation speeds in order to view phenomena that happen over long timescales. For astronomical calculations, Astrocalculator can be used to predict conjunctions, lunar eclipses, perform many common astronomical calculations; the following tools are included: Observation planner Sky calendar tool Script Builder Solar System Jupiter Moons Flags: Custom flags superimposed on the sky map.
FOV editor to display them. Altitude vs. Time tool to plot time graphs for any object. Hierarchical Progress Surveys overlay. High quality print outs for sky charts. Ekos is an astrophotography suite, a complete astrophotography solution that can control all INDI devices including numerous telescopes, CCDs, DSLRs, filters, a lot more. Ekos supports accurate tracking using online and offline astrometry solver, auto-focus and auto-guiding capabilities, capture of single or multiple images using the powerful built in sequence manager. KStars has been packaged by many Linux/BSD distributions, including Red Hat Linux, OpenSUSE, Mandriva Linux, Debian GNU/Linux; some distributions package KStars as a separate application, some just provide a kdeedu package, which includes KStars. KStars is distributed with the KDE Software Compilation as part of the kdeedu "Edutainment" module. KStars participated in Google Summer of Code in 2008, 2009, 2010, 2011 2012, 2015 and 2016, it has participated in the first run of ESA's Summer of Code in Space in 2011.
It has been identified as one of the three best "Linux stargazing apps" in a Linux.com review. The latest version of KStars is 3.0.0 which included improvements to the FITS Viewer tool and overhaul of the Ekos Scheduler. Aladin Sky Atlas C2A Cartes du Ciel Celestia Digital Universe Atlas Google Mars Google Moon Google Sky Hallo Northern Sky NASA World Wind RedShift Skyglobe Starry Night Stellarium TheSky Universe Sandbox WinStars WorldWide Telescope XEphem Official website MPC Elements for Comets and Minor Planets in KStars Download source code and Windows and Mac versions
500 Days of Summer is a 2009 American romantic comedy-drama film by first-time director Marc Webb from a screenplay written by Scott Neustadter and Michael H. Weber, produced by Mark Waters; the film stars Joseph Gordon-Levitt and Zooey Deschanel, employs a nonlinear narrative structure, with the story based upon its male protagonist and his memories of a failed relationship. As an independent production, the film was picked up for distribution by Fox Searchlight Pictures and premiered at the 25th Sundance Film Festival, it garnered favorable reviews and became a successful "sleeper hit", earning over $60 million in worldwide returns, far exceeding its $7.5 million budget. Many critics lauded the film as one of the best from 2009 and drew comparisons to other acclaimed films such as Annie Hall and High Fidelity; the film received Best Original Screenplay and Best Screenplay awards at the 14th Satellite Awards and 25th Independent Spirit Awards as well as two nominations at the 67th Golden Globe Awards: Best Motion Picture – Musical or Comedy and Best Actor – Musical or Comedy.
On January 8, Tom Hansen meets his boss' new assistant. Tom works as a writer at a greeting card company in Los Angeles. After discovering they have a similar taste in music, they have a conversation about love at a karaoke night. Tom's friend and co-worker McKenzie drunkenly reveals that Tom likes Summer, which Tom asserts is only "as friends", something Summer agrees with. A few days Summer kisses Tom in the office. During the next few months Summer and Tom grow closer. Tom shows Summer his favorite spot in the city, a park bench which overlooks a number of buildings he likes, though the view is somewhat spoiled by parking lots. After several months of dating, both Tom's friends and his preteen half-sister Rachel push him to question Summer where they are in their relationship, though Summer brushes this off, saying that it should not matter if they are both happy. One night, Tom gets into a fight with a man who tries to pick up Summer in a bar, which causes their first argument, they make up and Summer concedes Tom deserves some certainty, but that his demand that she promises to always feel the same way about him would be impossible for anyone to make.
On day 290, they are hanging out in a cafe. Tom wants to go back to Summer's place but she insists on seeing The Graduate and weeps at the ending, which surprises Tom as he'd always thought it was a romantic fairy tale, they visit the record store, but Summer is distracted, appears to have lost interest in Tom, kisses him good night. Tom tempts her with an offer of pancakes at a diner, where Summer casually announces that the relationship hasn't been working and breaks up with Tom while they are waiting for the food to arrive. Tom begins to sink into depression. Summer quits her job at the greeting card company. Tom's boss moves him to the consolations department, as his depression is making him unsuitable for happier events. Tom goes on a blind date with a woman named Alison; the date does not go well as he spends it complaining about Summer until an exasperated Alison ends up taking Summer's side. Months Tom attends co-worker Millie's wedding and tries to avoid Summer on the train, but she spots him and invites him for coffee.
They have a good time at the wedding, dance together, Summer catches the bouquet. She invites Tom to a party at her apartment and falls asleep on Tom's shoulder on the train ride back, he attends the party hoping to rekindle their relationship but gets to talk to Summer and spends most of the night drinking alone, until he spots her engagement ring. Tom leaves, close to tears, he enters a deep depression, only leaving his apartment for junk food. After a few days, he returns to work with a hangover and, after an emotional outburst, quits his job. Rachel tells Tom that she does not believe Summer was "the one" and that his depression is being worsened by the fact that he is only looking back on the positive aspects of their relationship. One day he finds the energy to get out of bed and rededicates himself to architecture, something Summer had pressured him to do, he makes a list of firms he wants to work for, assembles a portfolio, goes to job interviews. On day 488, Summer is waiting for Tom at his favorite spot in the city and they talk.
He informs her that he left the office, notes that she got married, which he admits he doesn't understand since she never wanted to be someone's girlfriend. Summer says she got married because she felt sure about something she wasn't with Tom; when Tom asserts that he was wrong about true love existing, she counters that he was right about it, he was just wrong about it being with her. Summer says she is glad to see he is doing well; as she leaves, Tom tells her he hopes she is happy. Twelve days on Wednesday, May 23, Tom attends a job interview and meets a girl, applying for the same job, he finds that she dislike for the parking lots. As he is entering the interview, he invites her for coffee afterwards, she politely declines changes her mind. Her name is Autumn. Joseph Gordon-Levitt as Tom Hansen, a trained architect who works as a writer at a greeting card company. Zooey Deschanel as Summer Finn, assistant to Tom's boss and Tom's love interest. Geoffrey Arend as McKenzie, Tom's co-worker at the greeting card company.
Chloë Grace Moretz as Rachel Hansen, Tom's younger half-sister. Matthew Gray Gubler as Paul, one of Tom's friends. Clark Gregg as Vance, Tom's boss. Patricia Belcher as Millie Rachel Boston as Alison, Tom's blind date. Minka Kelly
"Miss O'Dell" is a song by English musician George Harrison, released as the B-side of his 1973 hit single "Give Me Love". Like Leon Russell's "Pisces Apple Lady", it was inspired by Chris O'Dell, a former Apple employee, variously assistant and facilitator to musical acts such as the Beatles, Derek & the Dominos, the Rolling Stones, Bob Dylan and Santana. Harrison wrote the song in Los Angeles in April 1971 while waiting for O'Dell to pay him a visit at his rented home; as well as reflecting her failure to keep the appointment, the lyrics provide a light-hearted insight into the Los Angeles music scene and comment on the growing crisis in East Pakistan that led Harrison to stage the Concert for Bangladesh in August that year. Harrison recorded "Miss O'Dell" in England between October 1972 and February 1973, during the sessions for his Living in the Material World album; the arrangement reflects the influence of Dylan, the recording is notable for Harrison breaking into laughter midway through the verses.
A popular B-side, "Miss O'Dell" was unavailable for over 30 years after this initial release, until its inclusion as a bonus track on the 2006 reissue of Material World. An alternate, laughter-free vocal take of the song circulates on Harrison bootleg CDs and was included on the DVD accompanying the deluxe edition of Living in the Material World in 2006. O'Dell named her 2009 autobiography after the song. After arriving in London from Los Angeles in mid May 1968, to start work at the Beatles' Apple Corps headquarters at the invitation of her friend Derek Taylor, Chris O'Dell began a career that saw her become, in author Philip Norman's words, "the ultimate insider" in rock-music circles. In the space of two years, O'Dell witnessed first-hand a series of key moments in rock'n' roll: she joined in the backing chorus on the song "Hey Jude". In the 1970s, O'Dell went on to work with the Rolling Stones, during the LA sessions for Exile on Main St. and their subsequent "STP" US tour, on Crosby, Nash & Young's 1974 reunion tour and Dylan's Rolling Thunder Revue of 1975, but her heart would remain with the Beatles – her time with the Stones, she says, felt like a "climb down the ladder".
After working for Harrison and his wife Pattie Boyd during their first few months at Friar Park, from March to June 1970, she would always view the Henley estate as a spiritual home, the Harrisons as her most important friends in the fickle world of the music business. Adding to the list of what Britain's Daily Mail has described as her "certainly impressive" credentials, O'Dell assisted Harrison in preparing for the recording sessions for All Things Must Pass, helped him recruit musicians for the Bangladesh benefit concerts, served on his 1974 North American tour with Ravi Shankar, was privy to the details that ended the Harrisons' marriage as well as that of Ringo Starr and Maureen Starkey. By April 1971, O'Dell was back in California, working with former Apple Records A&R manager Peter Asher on developing the careers of singer-songwriters such as James Taylor, Carole King and Linda Ronstadt. At the same time, having contributed to the debut solo album by Bobby Whitlock of Derek & the Dominos, finished the Radha Krishna Temple album – both acts that O'Dell had been involved with professionally in 1969–70 – was now in Los Angeles to begin work on Shankar's Raga film soundtrack.
He had been informed of the tragic events occurring in Shankar's homeland, following the Bhola cyclone and the outbreak of the Bangladesh Liberation War. This was an issue that Harrison dealt with in the opening verse of a song he began writing, "Miss O'Dell", while waiting for his eponymous friend to visit him at his rented Malibu home: I'm the only one down here who's got Nothing to say about the war or the rice That keeps going astray on its way to Bombay... Adopting a more lighthearted approach than would be the case in his "storming, urgent" song "Bangla Desh" a couple of months these lines refer to international donations of rice, which "somehow" ended up becoming the property of the Indian Government instead and either being sold in government shops in India, or getting exported back to the West to be sold in Indian shops there, his disenchantment with the Californian surroundings and O'Dell's failure to turn up as arranged are reflected in the next lines: That smog that keeps polluting up our shores Is boring me to tears Why don't you call me, Miss O'Dell?
In verse two, Harrison describes the ocean-front house, the balcony of which stretched out over the waves below: I'm the only one down here who's got Nothing to fear from the waves or the night That keeps rolling on right up to my front porch... Inside the house, neither he nor his driver Ben could get the record player to work, Harrison admits to his absent friend over the song's middle eight: "I can tell you, nothing new / Has happened since I last saw you."In her 2009 memoir, O'Dell explains that her escalating drug habit had been responsible for her non-attendance on the evening in question, as well as a reluctance to have to put up with scores of hangers-on around the ex-Beatle. In the song's third verse, Harrison shows that he too had no interest in the typical trappings of the LA music scene: I'm the only one down here who's got Nothing to say about the hip or the dope Or th
Limulus amebocyte lysate is an aqueous extract of blood cells from the Atlantic horseshoe crab, Limulus polyphemus. LAL reacts with bacterial endotoxin lipopolysaccharide, a membrane component of gram-negative bacteria; this reaction is the basis of the LAL test, used for the detection and quantification of bacterial endotoxins. In Asia, a similar Tachypleus amebocyte lysate test based on the local horseshoe crabs Tachypleus gigas or Tachypleus tridentatus is used instead; the recombinant factor C assay is a replacement of LAL/TAL based on a similar reaction. Fred Bang reported in 1956 that gram-negative bacteria if killed, will cause the blood of the horseshoe crab to turn into a semi-solid mass, it was recognized that the animal's blood cells, mobile cells called amoebocytes, contain granules with a clotting factor known as coagulogen. The resulting coagulation is thought to contain bacterial infections in the animal's semi-closed circulatory system. Modern analysis of the lysate has lead to understanding of this system of cascade, with multiple enzymes working in sequence to produce the gel.
The entry point of endotoxin-induced clotting is Limulus clotting factor C. In 1977 the U. S. Food and Drug Administration approved LAL for testing drugs and devices that come in contact with the blood. Prior to that date, a much slower and more expensive test on rabbits had been used for this purpose. Horseshoe crabs are collected and blood is removed from the horseshoe crab's pericardium. LAL manufacturers have measured mortality rates of 3% in bled crabs; the blood cells are separated from the serum using centrifugation and are placed in distilled water, which causes them to swell and burst. This releases the chemicals from the inside of the cell, purified and freeze-dried. To test a sample for endotoxins, it is mixed with water. There are three basic methodologies: gel-clot and chromogenic; the primary application for LAL is the testing of parenteral pharmaceuticals and medical devices that contact blood or cerebrospinal fluid. In the United States, the FDA has published a guideline for validation of the LAL test as an endotoxin test for such products.
The LAL cascade is triggered by -β-D-glucan, via a different Factor G. Both bacterial endotoxins and -β-D-glucan are considered pathogen-associated molecular patterns, or PAMPs, substances which elicit inflammatory responses in mammals. One of the most time-consuming aspects of endotoxin testing using LAL is pretreating samples to overcome assay inhibition that may interfere with the LAL test such that the recovery of endotoxin is affected. If the product being tested causes the endotoxin recovery to be less than expected, the product is inhibitory to the LAL test. Products which cause higher than expected values are enhancing. Overcoming the inhibition and enhancement properties of a product is required by the FDA as part of the validation of the LAL test for use in the final release testing of injectables and medical devices. Proper endotoxin recovery must be proven; the LAL test makes up a great source of animal product dependence in the biomed industry, with reports of the higher-than anticipated mortality rate, it was considered more ethical to try to move away from the test.
Since 2003, a synthetic substitute for the LAL test has been commercially available. Named the recombinant factor C assay, it is based on the same Limulus clotting factor C protein, produced by genetically modified organisms like insect gut cells. Instead of emulating the whole clotting pathway, rFC tests let factor C cleave a fluorogenic molecule, so that the sample lights up when endotoxin activates the factor. Since it does not contain factor G, -β-D-glucan will not cause false-positives; as of 2018, available evidence considers the rFC test no worse than the LAL test. The adoption of this test was slow, which began to change in 2012 when the US FDA and the European health ministry acknowledged it as an accepted alternative, its lack of mention in Pharmacopeias remained an issue, as there was no good standard for running the test in production. In 2016, it was added to the European Pharmacopoeia. A patent on rFC limited adoption until it expired in 2018; the monocyte activation test is another proposed method to test for endotoxins based on monocytes in human blood.
It measures the release of cytokines from these due to the presence of pyrogens mirroring the process by which these toxins cause fever in humans. A protocol for the MAT test, using cultured cells, is described in the European Pharmacopeia. Limulus clotting enzyme Lipopolysaccharide horseshoecrab.org LAL Update Endotoxin Detection Product 1987 FDA LAL test guideline
Ebenezer Beesley was a Latter-day Saint hymn writer and composer. The music for twelve of the hymns in the 1985 English-language hymnal of The Church of Jesus Christ of Latter-day Saints was written by him. Beesley was born in Bicester, England, his parents joined the LDS Church when he was quite young and he was baptized a member of the church on 22 September 1849. In 1859, Beesley emigrated to Utah Territory in the George Rowley Handcart Company with his family, including first wife Sarah Hancock Beesley, they first lived in Tooele, but they moved to Salt Lake City. In the 19th Ward in Salt Lake City, Beesley served as both choir director and music director for Sunday School, he studied under George Careless. In 1863, Beesley joined the Salt Lake Theatre Orchestra. In 1869 he had 6 children with her, he became the father of 16 children in total between the years 1860 and 1883. Beesley was a contributor to the Juvenile Instructor magazine, he was one of the men appointed by John Taylor to oversee the publication of the 1860 Latter-day Saints' Psalmody, the first LDS Church hymnbook to include music.
In 1880, Beesley became the director of the Mormon Tabernacle Choir. In September of that year, Beesley led the choir's first excursion outside of Salt Lake City on a trip to American Fork, Utah where they performed with the local choir for a large group of citizens. Beesley served as the choir director until 1889. After serving with the Mormon Tabernacle Choir, Beesley taught music in Tooele, for a time in Lehi, Utah, he moved back to Salt Lake City where he died. In the 1985 LDS Church hymnal the music for the following hymns was composed by Beesley: 5 "High on the Mountain Top" 16 "What Glorious Scenes Mine Eyes Behold" 32 "The Happy Day at Last Has Come" 76 "God of Our Fathers, We Come unto Thee" 77 "Great Is the Lord" 156 "Sing We Now at Parting" 177 "Tis Sweet to Sing the Matchless Love" Tune name=Hancock 185 "Reverently and Meekly Now" 232 "Let Us Oft Speak Kind Words" 280 "Welcome, Sabbath Morning" 282 "We Meet Again in Sabbath School" Ebenezer Beesley House Works by or about Ebenezer Beesley at Internet Archive
The State Savings Bank of Ukraine, or Oschadbank, is a public joint-stock company based in Ukraine. It was established by Decree of the Cabinet of Ministers of Ukraine on May 21, 1999, through the transformation of its predecessor, the State Specialized Commercial Savings Bank of Ukraine into a Joint-Stock Company; the State Savings Bank of Ukraine is one of the largest financial institutions of Ukraine and one of three systemically important banks nominated by National Bank of Ukraine every year since 2015 when classification requirement came into force. By the end of 2016, the bank had 3,650 branches and 2,850 ATMs throughout the country which carry out various functions, such as the disbursement of pensions, social aid, processing of utility payments and other banking transactions. Together with PrivatBank, Oschadbank is one of the only two Ukrainian banks whose clients' time deposits are guaranteed by state law compared to total of 200,000 in other banks in case of bank liquidation. List of banks in Ukraine Official website