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In Hawaiian mythology, the Kupua are a group of supernatural entities which might be considered gods or spirits. Hawaiian myths and legends abound with such characters, they are traditionally described as monsters having the power of appearing in different kinds of bodies. They have cruel and vindictive characters and are ready to destroy and devour any persons they can catch. There are, many kupuas of kindly spirit who give watchful care to the members of their own families. Many Hawaiian kupua are considered as gods having a double body, sometimes appearing as a man and sometimes being able to change shape, into an animal, vegetable, or mineral form; the latter form always possesses supernatural powers. William Westervelt mentions the following classification for kupua: Ka-poe-kino-lau Ka-poe-kino-pua Ka-poe-kino-manu Ka-poe-kino-laau Ka-poe-kino-pupu Ka-poe-kino-ao Ka-poe-kino-maani Ka-poe-kina-ia Ka-poe-kina-mano Ka-poe-kina-limu Ka-poe-kina-pokaku Ka-poe-kina-hiwa-hiwa Mamala the surf-rider was a chiefess of kupua character.

She is described as gigantic lizard or crocodile, as well as a beautiful woman. She could assume. One of the legends says that she was a woman. In an old Honolulu legend, a kupua, a dog-man overthrows the government of Kahanai and becomes the ruling power between Nuuanu Valley and the sea, he is a cannibal and many of the people are killed and eaten by him. He can appear as a man or a dog. In Maui, the king once had a kupua, a rooster, cruel and destructive, he could assume a different bird form for each magic power. This, with his miraculous human powers, made him superior to all the roosters, his antagonists in cock-fighting. In Kauai, Akua-pehu-ale was a kupua who devoured his enemies and was feared and hated by his own tribe. In the legend of the bread-fruit tree, one of the ancestors of the people living in all the islands now known as Polynesia, is described as a kupua, her daughter Kap-ula-kinau has kupua, or magic power. Other Hawaiian kupua mentioned in the mythology include the famous trickster Māui, Iwa and Pekoi.

See Apukohai. Pukui, Mary Kawena and Samuel H. Elbert. Hawaiian Dictionary. University of Hawaii Press. Rose, Carol. Spirits, Fairies and Goblins: An Encyclopedia. ABC-Clio, p. 176. Westervelt, W. D.. Legends of Old Honolulu. Westervelt, W. D.. Hawaiian Legends of Ghosts and Ghost Gods

I Am What I Am (Village People song)

"I Am What I Am" is a song written by Victor Willis, Henri Belolo, Peter Whitehead and Jacques Morali, first released by the Village People on their 1978 album Macho Man. It was released as a single with "Key West," from Macho man, as the b-side in some countries including Germany and the UK, it did not chart in those countries, but it reached #4 on the Billboard Dance Chart in a medley with "Key West" and "Macho Man." It has since been released on several Village People greatest hits compilation albums. It was included on the soundtrack for the 1978 film Thank God It's Friday. Rolling Stone critic Mitchell Schneider described "I Am What I Am" as a "human-rights anthem." Village People singer Randy Jones describes the song as "a gay liberation statement, aimed directly at gays and lesbians who were standing up without apology for their lifestyle" and as the group's "first gay liberation song." He says that the theme of the song is the virtue of being yourself, not just if you're gay or transgender but just if you want to dress in an unusual manner, as long as you don't hurt anyone else.

Author Michael DeAngelis describes the theme as being "pride and faithfulness to the individual and authentic self." DeAngelis notes that this theme had particular resonance at the time, when the gay community was in the process of "coming out" and a general cultural obsession was finding healthy ways to feel good about oneself. Author Frédéric Martel identifies "I Am What I Am" as one of five Village People songs that were touchstones to the gay movement in France when they came out. Author Judith A. Peraino described "I Am What I Am" as a "hit single" while Boze Hadleigh described it as a "pre-hit." Author Sharon Davis claimed that lyrics are "so camp they have to held down with tent pegs." But Billboard described it as "provocative," describing it as a "gay pride anthem with its activist lyrics and basic theme." Billboard praised the rhythm and percussion and horn arrangements. AllMusic critic Amy Hanson described it as "a well-constructed slab of groove," despite lacking subtlety. Rolling Stone critic Mitchell Schneider regarded "I Am What I Am" as the best song on Macho Man stating that Willis' voice is "full of anger and delight" on the song and concluding that "because the song seems so committed, it makes the rest of the material sound downright pointless."The song's title was reused by Jerry Herman for a 1983 hit song performed by Gloria Gaynor, which had gay pride as a theme.

Reebok used the title phrase for a successful trainers advertising campaign. The b-side of the "I Am What I Am" single was "Key West." Like "I Am What I Am," "Key West" was part of the medley that reached #4 on the Billboard Dance Chart and Peraino described "Key West" as a "hit single". Jones described "Key West" as "a salute to the Florida town that Ernest Hemingway and Tennessee Williams, along with gay men and women, had made a vacation destination." He noted that it is a "gay friendly resort", so "different-thinking" that it remained in the Union despite Florida seceding in the Civil War. Author Chuck Eddy describes "Key West" as one of the Village People's "small hits" and one of several of their songs to "stump for substitute utopias...where there's plenty of'unity,"happiness,"liberation' and'togetherness.' "Key West" has been included on several Village People greatest hits compilation albums. Lyrics of this song at MetroLyrics

Alberto Botía

Alberto Tomás Botía Rabasco is a Spanish professional footballer who plays as a central defender for Saudi Arabian club Al-Wehda Club. He made 140 La Liga appearances for Sporting de Gijón but Sevilla and one for Barcelona, where he started his career. Additionally, he spent four years with Olympiacos. Botía was born in Region of Murcia. Aged just eight years old he began playing for CD Beniel, soon joining neighbours Real Murcia and remaining there for three years. In 2003 he moved to FC Barcelona. In late May 2009 Botía, alongside fellow youth graduate Marc Muniesa, was first called to the main squad for a UEFA Champions League match against Manchester United, he made his official debut on the 30th, coming on as a second-half substitute for Gerard Piqué in the final game of the campaign, a 1–1 away draw against Deportivo de La Coruña. On 14 July 2009, Botía was sent to fellow La Liga club Sporting de Gijón on a season-long loan. A regular starter throughout his first year in the top tier, he decided to extend his stay with the Asturians in a four-year deal, with Barcelona keeping a buy-back clause for the first three.

Botía scored his first top-flight goal on 12 September 2010, opening a 2–0 home win over RCD Mallorca. On 14 November, he was sent off in the last minute of a 1–0 loss to Real Madrid CF at El Molinón for a foul on Cristiano Ronaldo. On 8 August 2012, following Sporting's relegation, Botía signed with Sevilla FC for a fee believed to be in the region of €3 million, he was brought in with the help of an Anglo-Portuguese investment firm. He made his official debut for his new team 18 days playing the second half of a 1–1 away draw against Granada CF. On 23 February 2013, Botía put the visitors ahead at former side Barcelona, but in an eventual 1–2 loss. For the 2013–14 campaign, after 25 official appearances for the Andalusian team, he was loaned to Elche CF alongside teammates Manu del Moral and Miroslav Stevanović. Botía's spell at the Estadio Martínez Valero ended prematurely on 3 May 2014, when he was ejected for kicking the ball at a Málaga CF player in a 0–1 home loss and confronted the referee, earning him a two-match suspension.

On 1 August 2014, Botía joined Greek club Olympiacos F. C. on a four-year contract, for €2 million. He contributed with 25 appearances all competitions comprised in his debut season, helping them win the double. Botía was regularly played in 2015–16, under new manager Marco Silva. On 25 October 2015, he scored both of his team's goals in a 2–1 away victory over Atromitos FC, becoming the club's first defender to achieve this since Avraam Papadopoulos two years earlier. On 6 November 2016, Botía netted the opening goal of a 3–0 home defeat of Panathinaikos F. C. in the Derby of the eternal enemies. His contract was terminated by mutual consent on 4 May 2018. Botía became new manager Jorge Jesus' first signing for Al-Hilal FC on 26 June 2018, when the 29-year-old agreed to a two-year deal with the option for a further season. On his debut on 18 August, the club won the Saudi Super Cup with a 2–1 win over Al-Ittihad Club at Loftus Road, London. After the Riyadh-based side finished runners-up to Al-Nassr FC, Botía left for Al-Wehda Club of the Saudi Professional League.

He scored the equaliser on a 2 -- 1 home loss to Abha Club on 30 August. On 7 February 2007, Botía was summoned for the Spanish under-19 team, being an unused squad member at the "XXXIII International Atlantic Cup". Two years he received his first under-21 callup, for a friendly with Norway. On 25 August 2011, Botía was selected for the first time to the full side by manager Vicente del Bosque, for games against Chile and Liechtenstein, he was included in Luis Milla's squad for the 2012 Summer Olympics, playing the last two matches against Honduras and Morocco as the team were eliminated without scoring a goal. As of 11 January 2020 Barcelona La Liga: 2008–09Olympiacos Superleague Greece: 2014–15, 2015–16, 2016–17 Greek Football Cup: 2014–15.

Cholesterol side-chain cleavage enzyme

Cholesterol side-chain cleavage enzyme is referred to as P450scc, where "scc" is an acronym for side-chain cleavage. P450scc is a mitochondrial enzyme; this is the first reaction in the process of steroidogenesis in all mammalian tissues that specialize in the production of various steroid hormones. P450scc is a member of the cytochrome P450 superfamily of enzymes; the gene name is CYP11A1. The systematic name of this enzyme class is cholesterol, reduced-adrenal-ferredoxin:oxygen oxidoreductase. Other names include: The highest level of the cholesterol side-chain cleavage system is found in the adrenal cortex and the corpus luteum; the system is expressed at high levels in steroidogenic theca cells in the ovary, Leydig cells in the testis. During pregnancy, the placenta expresses significant levels of this enzyme system. P450scc is present at much lower levels in several other tissue types, including the brain. In the adrenal cortex, the concentration of adrenodoxin is similar to that of P450scc, but adrenodoxin reductase is expressed at lower levels.

Immunofluorescence studies using specific antibodies against P450scc system enzymes have demonstrated that proteins are located within the mitochondria. P450scc is associated with the inner mitochondrial membrane. Adrenodoxin and adrenodoxin reductase are soluble peripheral membrane proteins located inside the mitochondrial matrix that appear to associate with each other through electrostatic interactions. P450scc catalyzes the conversion of cholesterol to pregnenolone in three monooxygenase reactions; these involve 2 hydroxylations of the cholesterol side-chain, which generate, first, 22R-hydroxycholesterol and 20alpha,22R-dihydroxycholesterol. The final step cleaves the bond between carbons 20 and 22, resulting in the production of pregnenolone and isocaproic aldehyde; each monooxygenase step requires 2 electrons. The initial source of the electrons is NADPH; the electrons are transferred from NADPH to P450scc via two electron transfer proteins: adrenodoxin reductase and adrenodoxin. All three proteins together constitute the cholesterol side-chain cleavage complex.

The involvement of three proteins in cholesterol side-chain cleavage reaction raises the question of whether the three proteins function as a ternary complex as reductase:adrenodoxin:P450. Both spectroscopic studies of adrenodoxin binding to P450scc and kinetic studies in the presence of varying concentrations of adrenodoxin reductase demonstrated that the reductase competes with P450scc for binding to adrenodoxin; these results demonstrated. From these studies, it was concluded that the binding sites of adrenodoxin to its reductase and to P450 are overlapping and, as a consequence, adrenodoxin functions as a mobile electron shuttle between reductase and P450; these conclusions have been confirmed by structural analysis of P450 complex. The process of electron transfer from NADPH to P450scc is not coupled. Steroidogenic cells include a diverse array of antioxidant systems to cope with the radicals generated by the steroidogenic enzymes. In each steroidogenic cell, the expression of the P450scc system proteins is regulated by the trophic hormonal system specific for the cell type.

In adrenal cortex cells from zona fasciculata, the expression of the mRNAs encoding all three P450scc proteins is induced by corticotropin. The trophic hormones increase CYP11A1 gene expression through transcription factors such as steroidogenic factor 1, by the α isoform of activating protein 2 in the human, many others; the production of this enzyme is inhibited notably by the nuclear receptor DAX-1. P450scc is always active, however its activity is limited by the supply of cholesterol in the inner membrane; the supplying of cholesterol to this membrane is, considered the true rate-limiting step in steroid production. This step is mediated by the steroidogenic acute regulatory protein. Upon stimulation of a cell to make steroid, the amount of StAR available to transfer cholesterol to the inner membrane limits how fast the reaction can go. With prolonged stimulation, it is thought that cholesterol supply becomes no longer an issue and that the capacity of the system to make steroid is now more important.

Corticotropin is a hormone, released from the anterior pituitary in response to stress situations. A study of the steroidogenic capacity of the adrenal cortex in infants with acute respiratory disease demonstrated that indeed during disease state there is a specific increase in the steroidogenic capacity for the synthesis of the glucocorticoid cortisol but not for the mineralocorticoid aldosterone or androgen DHEAS that are secreted from other zones of the adrenal cortex. Mutations in the CYP11A1 gene result in a steroid hormone deficiency, causing a minority of cases of the rare and fatal condition lipoid congenital adrenal hyperplasia. Steroidogenic enzyme Cytochrome P450 oxidase Cytochrome+P450scc at the US National Library of Medicine Medical Subject Headings

Relman Morin

Relman George Morin was an American journalist who spent most of his career writing for the Associated Press, serving as bureau chief of its offices in Tokyo, Washington, D. C. and New York. Arrested by the Japanese in Saigon on the day after the attack on Pearl Harbor, Morin was held prisoner for six months, he reported from the European front during World War II and was present at the signing of the peace treaty between the Allies and Germany. He was a war correspondent during the Korean War, he won the Pulitzer Prize twice, once for his Korean War reportage and once for his reportage on the Little Rock school integration crisis in 1957. Morin was born in Freeport and raised in Los Angeles, California, he graduated from a Los Angeles high school in 1925 went on to study at Pomona College. He began his journalism career by working as an office boy and part-time sports reporter for the Los Angeles Times while in high school and college, he graduated from Pomona in 1929. He went to study in China, first at Lignan University in Canton, where he was a "special student," at Yenching University in Peking.

In 1930, while in China, he worked as a reporter for the Shanghai Evening Post. Returning to the U. S. Morin wrote movie columns for the Los Angeles Record from 1932 to 1934, he joined the Associated Press in 1934. He would remain with the AP for 40 years, serving as Los Angeles editor, Tokyo bureau chief, Far East correspondent, war correspondent. C.. In New York he served as general executive at AP headquarters from 1949 to 1950. Morin was in Mongolia in 1939. In December 1940, he began a one-year roving assignment through southeast Asia. In seeking to explore areas lying in the path of Japanese expansion, he visited the regions known as the Netherlands East Indies, French Indo-China, the British colony of Singapore, independent Thailand, as well as Shanghai and Manila, he spent six months in Java during the protracted economic negotiations between Japan and the Netherlands Indies. He was present to cover the Japanese occupations of both French Indo-China, he was beaten by Thai soldiers, was arrested by the Japanese in Saigon on December 8, 1941, "closely examined on espionage charges."

From December 1941 to August 1942, he was imprisoned by the Japanese secret police, who "threatened him with torture if he did not write treasonable propaganda for Japanese broadcasts." He returned to the U. S. in September 1942, in the spring of 1943 crossed the Atlantic to report on the war in the European theater. He considered the Dutch Empire to be more "wise and kindly" than others, but he was "no apologist for empire," wrote Orville Prescott. "No recent writer disgusted with the snobbery and general dry rot of Singapore has been more outspoken than he."His essay "In a Schoolhouse at Rheims, Four Copies Were Signed" is an eyewitness account of the surrender of Wehrmacht chief Colonel general Alfred Jodl, German Navy commander General admiral Hans-Georg von Friedeburg, Major G. S. Wilhelm Oxenius, to Allied officers, including General Carl A. Spaatz and Lieutenant general Walter Bedell Smith, at 2:47 A. M. On May 7, 1945. In the essay, Morin wrote: "'There are four copies to be signed.' Gen. Smith’s voice was cold, matter-of-fact.

He spoke without haste. Neither tone nor cadence hinted at his feelings.... There was a moment of silence, in that moment, the scene seemed to freeze, it had the character of a picture, somehow, a queer unreality. Here was the end of nearly five years of war, of blood and death, of high excitement and fear and great discomfort, of explosions and bullets whining and the wailing of air raid sirens. Here, brought into this room, was the end of all that. Your mind refused to take it in. Hence, this was a dream, this room with the Nile green walls and the charts, the black table, the uniformed men seated around it; the words,'There are four copies to be signed,' meant nothing unless you forced the meaning to come, ramming it into your brain with a hard, conscious effort.... And the documents were being passed across to the Germans, they were signing them, they were signing away the Luftwaffe and the submarines. Their pens scratched and the State, to have lasted a thousand years died."In July 1950 he went to Tokyo on assignment, when the Korean War began he went to Korea to report from the front.

He witnessed the execution of Julius and Ethel Rosenberg on June 19, 1953. He had a heart attack that sidelined him for several months in 1955. In 1957, he reported on the school integration crisis at Little Rock High School. From a phone booth near the school, he "calmly dictated" his story of "how Negro students slipped in a side entrance past an unruly mob." This won him his second Pulitzer Prize. He died in New York City. Morin wrote Circuit of Conquest about his travels in his detention by the Japanese. Reviewing the book in the New York Times, Orville Prescott called it "one of the best books on the decline and fall of Western power in the Far East" and stated that while several of the other journalists, detained by the Japanese had published accounts of their experiences, Morin's book "makes up for its lack of spot news value with intelligent, considered judgment and an unusually high quality of narrative skill.... About the places where he sojourned only Mr Morin writes with the verve and sharp eye for dramatic detail of the best kind of person

Banay-Banay, Cabuyao

Barangay Banay-Banay is one of the eighteen urbanized barangays comprising the progressive City of Cabuyao in the province of Laguna, Philippines. It lies for about 2.5 kilometers away from the city proper of Cabuyao and is situated at the central portion of the city. According to the 2010 Census, it has a population of 21,934 inhabitants, making it ranked as 4th largest barangay in Cabuyao when it comes to population. Barangay Banay-Banay is popular for being the site of the town's own university, the Pamantasan ng Cabuyao, where a big number of students are studying there; the total land area of Barangay Banay-Banay is 310.12 hectares or 3.1012 square kilometers, ranking sixth out of eighteen barangays in the city of Cabuyao when it comes to land area. It lies for about 2.5 kilometers away from the city proper and is situated along the National Highway. It is located north of Brgy. Pulo, east of Brgy. Diezmo, south of Brgy. Niugan and west of Brgy. Gulod in Cabuyao, Laguna, it is one of the six barangays of the town along the National Highway while the others are Barangays Banlic, Pulo and San Isidro.

The rainfall regime of Barangay Banay-Banay is characterized by the two pronounced seasons, the wet and dry seasons. The wet season, from June to November and the dry season that lasts from December to May; the average rainfall is about 2,000 mm of rain falling in an average year, there are about 150 days which are rainy days. The seasonal variations of the Temperature field is uneventful; the coldest months start from November up to January and the warmest month on the record is the month of May. On the average, a 12 °C temperature difference exists between the coolest months; the mean annual temperature is a warm 27.5 °C. The annual relative Humidity is 70%; the most humid months are June, July and September with the normal relative humidity registered at 84%, while April and May are the driest at 70%. According to 2010 Census, it has a population of 21,934 inhabitants, grew from 17,419 in Census 2007. Barangay Captain: Eric E. Barron Sangguniang Barangay Members Christopher C. de Leon Cenon C.

Marcha Rafael N. Pampang Anwar U. Aidarus Danica E. Gabriel Noel B. Caparas Cabuyao, Laguna Laguna, Philippines Pamantasan ng Cabuyao Official Website of the City of Cabuyao Cabuyao Laguna Site The Spirit of Cabuyao