McComb is a city in Pike County, Mississippi, United States. The city is approximately 80 miles (130 km) south of Jackson. As of the 2010 census, the city had a total population of 12,790. It is the principal city of the McComb, Mississippi Micropolitan Statistical Area.

Pike County is a county located on the southwestern border of the U.S. state of Mississippi. As of the 2020 census, the population was 40,324. The county seat is Magnolia. Pike County is named for explorer Zebulon Pike. Pike County is part of the McComb, MS Micropolitan Statistical Area.