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Metabolic syndrome

Metabolic syndrome is a clustering of at least three of the five following medical conditions: central obesity, high blood pressure, high blood sugar, high serum triglycerides, low serum high-density lipoprotein. Metabolic syndrome is associated with the risk of developing cardiovascular disease and type 2 diabetes. In the US about a quarter of the adult population has metabolic syndrome, the prevalence increases with age, with racial and ethnic minorities being affected. Insulin resistance, metabolic syndrome, prediabetes are related to one another and have overlapping aspects; the syndrome is thought to be caused by an underlying disorder of energy storage. The cause of the syndrome is an area of ongoing medical research; the key sign of metabolic syndrome is central obesity known as visceral, male-pattern or apple-shaped adiposity. It is characterized by adipose tissue accumulation predominantly around trunk. Other signs of metabolic syndrome include high blood pressure, decreased fasting serum HDL cholesterol, elevated fasting serum triglyceride level, impaired fasting glucose, insulin resistance, or prediabetes.

Associated conditions include hyperuricemia. The exact mechanisms of the complex pathways of metabolic syndrome are under investigation; the pathophysiology is complex and has been only elucidated. Most people affected by the condition are older, obese and have a degree of insulin resistance. Stress can be a contributing factor; the most important risk factors are diet, aging, sedentary behavior or low physical activity, disrupted chronobiology/sleep, mood disorders/psychotropic medication use, excessive alcohol use. There is debate regarding whether obesity or insulin resistance is the cause of the metabolic syndrome or if they are consequences of a more far-reaching metabolic derangement. A number of markers of systemic inflammation, including C-reactive protein, are increased, as are fibrinogen, interleukin 6, tumor necrosis factor-alpha, others; some have pointed to a variety of causes, including increased uric acid levels caused by dietary fructose. Research shows that Western diet habits are a factor in development of metabolic syndrome, with high consumption of food, not biochemically suited to humans.

Weight gain is associated with metabolic syndrome. Rather than total adiposity, the core clinical component of the syndrome is visceral and/or ectopic fat whereas the principal metabolic abnormality is insulin resistance; the continuous provision of energy via dietary carbohydrate and protein fuels, unmatched by physical activity/energy demand creates a backlog of the products of mitochondrial oxidation, a process associated with progressive mitochondrial dysfunction and insulin resistance. Recent research indicates prolonged chronic stress can contribute to metabolic syndrome by disrupting the hormonal balance of the hypothalamic-pituitary-adrenal axis. A dysfunctional HPA-axis causes high cortisol levels to circulate, which results in raising glucose and insulin levels, which in turn cause insulin-mediated effects on adipose tissue promoting visceral adiposity, insulin resistance and hypertension, with direct effects on the bone, causing "low turnover" osteoporosis. HPA-axis dysfunction may explain the reported risk indication of abdominal obesity to cardiovascular disease, type 2 diabetes and stroke.

Psychosocial stress is linked to heart disease. Central obesity is a key feature of the syndrome, being both a sign and a cause, in that the increasing adiposity reflected in high waist circumference may both result from and contribute to insulin resistance. However, despite the importance of obesity, affected people who are of normal weight may be insulin-resistant and have the syndrome. Physical inactivity is a predictor of related mortality. Many components of metabolic syndrome are associated with a sedentary lifestyle, including increased adipose tissue. Compared with individuals who watched television or videos or used their computers for less than one hour daily, those who carried out these behaviors for greater than four hours daily have a two fold increased risk of metabolic syndrome. Metabolic syndrome affects 60% of the US population older than age 50. With respect to that demographic, the percentage of women having the syndrome is higher than that of men; the age dependency of the syndrome's prevalence is seen in most populations around the world.

The metabolic syndrome quintuples the risk of type 2 diabetes mellitus. Type 2 diabetes is considered a complication of metabolic syndrome. In people with impaired glucose tolerance or impaired fasting glucose, presence of metabolic syndrome doubles the risk of developing type 2 diabetes, it is that prediabetes and metabolic syndrome denote the same disorder, defining it by the different sets of biological markers. The presence of metabolic syndrome is associated with a higher prevalence of CVD than found in people with type 2 diabetes or IGT without the syndrome. Hypoadiponectinemia has been shown to increase insulin resistance, is considered to be a risk factor for developing metabolic syndrome; the approximate prevalence of the metabolic syndrome in people with coronary artery disease is 50%, with a prevalence of 37% in people with pre


Finnsbu was a Norwegian hunting and radio station located on the King Frederick VI Coast, Southeastern Greenland. Administratively the area were the hut; the station was located on the shore of Graah Fjord, in the much indented coast of southern Thorland. Finnsbu was part of a sovereignty claims staked by Norway in Southeast Greenland between 60°30'N —just north of Nanuuseq, 63°40'N —just south of Odinland. In 1931 Norway sent two expeditions to establish hunting and radio stations in Southeast Greenland. Finn Devold, Hallvard Devold's brother, on ship Heimen from Tromsø, led the bigger party of six hunters to establish a Norwegian station. Devold went to Timmiarmiut Fjord, but he moved north to Skjoldungen District and built the hut by a good harbor in southern Thorland, naming it Finnsbu after his own name. Devold's team built two other main stations, as well as a number of smaller huts in the same region; the other expedition, led by Ole Mortensen, went to Storfjord on ship Signalhorn and built a hut there.

Since hunting there was poor, Mortensen moved with his men south to Lindenow Fjord, where a station named Moreton was built, moved by Gunnar Horn to neighboring Nanuuseq Fjord and renamed Torgilsbu. On 12 July 1932 Devold was required by the Norwegian government to formally hoist the Norwegian flag at Finnsbu. An expedition sent by the government led by Gunnar Horn on ship Veslemari visited Finnsbu on 17 August the same year. Together with Torgilsbu further south, Finnsbu became part of the Norwegian contribution to the International Polar Year 1932–33. In July 1933 Finnsbu station sent meteorological data to the Decennial Air Cruise squadron of Italian seaplanes led by Italo Balbo. Following the 1933 resolution of the Permanent Court of International Justice rejecting Norway's claims in Greenland Finnsbu was abandoned. Relief ship Signalhorn evacuated the staff of the stations in the Storfjord and Skjoldungen area and brought them back to Norway in August 1933. Torgilsbu, remained in operation until 1940.

There is a tide gauge in the location of the former Norwegian settlement. Spencer Apollonio, Lands That Hold One Spellbound: A Story of East Greenland, 2008 Erik the Red's Land Norwegian Polar Year and Radio Stations in East Greenland, 1932–33 Anders Christian Feyling, Torgilsbu 1933-34: dagbok ført av radiostasjonens bestyrer The World at War - Greenland 1721 - 1953

Van Ness station

Van Ness station is an underground Muni Metro station on the Market Street Subway at the intersection of Market Street and Van Ness Avenue in San Francisco, California. The station consists of a concourse mezzanine on the first floor down, a single island platform on the second level down. Service at the station began in February 1980; the station has suffered flooding during heavy rainstorms, including one in October 2009, another in December 2014 which damaged an electrical equipment room. In February 2017, the SFMTA signed a $1.9 million contract to repair water-damaged wiring in the room. Under the proposed Western Variant of the planned Better Market Street project, the outbound F stop would be moved across the intersection. Media related to Van Ness station at Wikimedia Commons

A. N. Field

Arthur Nelson Field was a New Zealand journalist and political activist. Born in Nelson he was the first son of four children born to Jessica Black, his father was managing director of Wilkins and Field Hardware in his native city, which his grandfather had founded, served as a Nelson City Councillor and Reform Party member of parliament for the Nelson electorate from 1914 to 1919. Field took up journalism and worked as a reporter for The Evening Post, Taranaki Herald, Poverty Bay Herald and Melbourne Argus, before returning to Nelson in 1907, he served as a Wellington Dominion columnist for the next 21 years. There was a break during this period when he served as a Royal Navy sub-lieutenant and adjutant at Portsmouth, on board RNV Spenser in the North Sea, he returned to New Zealand when discharged in 1914. While working as a journalist and serving in the Navy, Field became involved in right-wing politics. In 1909 he published The Citizen, an early far right publication which upheld motherhood and monetary reform, opposed "Maori Obstructionism" for seven years, 1912-1919.

After that period, he became involved with "The Britons", a group that specialised in publishing New Zealand editions of The Protocols of the Learned Elders of Zion and published a New Zealand edition himself. During the Second World War, he was kept under surveillance by the Security Intelligence Bureau of New Zealand's Department of External Affairs. Field won "acclaim" from kindred anti-socialists such as the League of Empire Loyalists and the late Eric Butler of the Australian League of Rights. Marcus van Rooij wrote a paper on A. N. Field's influence on Australian neofascism, suggesting his conspiracy theory discourse impacted on other such Australian organisations during the Depression era. In particular, The Truth About the Slump enjoyed widespread circulation and stimulated the interest of organisations such as the Guild of Watchmen of Australia, the Australian Catholic Truth Society, the League of Truth, the British Australian Racial Body, Evangelical Publishing Company of New South Wales.

Australian anti-Semite Patricia Lewin cited Truth About the Slump in her tract, The Key, as did numerous other Australian Social Credit and Douglas Credit Party figures that based their work on the monetary theories of C. H. Douglas. Rooij designated him the "Kiwi theoretician of the Australian Radical Right". Field was a creationist, he authored the book. It was republished in 1971 under the title The Evolution Hoax Exposed. Despite the recognition of his work in Australia and the United States, the circulation of his books within those countries, Field preferred to work from his isolated Nelson homestead. In his years, Field wrote a series of self-published tracts on his interpretations of economics, anti-socialist articles about the New Zealand Labour Party and trade union movement, related matters; some were republished in the United States in the early 1960s. Field died aged 81 in a private hospital in Nelson, his collected tracts and monographs were deposited in the Alexander Turnbull Library of the National Library of New Zealand in 1968.

Wanted: Accurate Data about Human Heredity. Timaru: Timaru Post Publishing, 1911. Medical Marriage Certificates. London: Eugenic Education Society, 1912; the Defence Department's Failure. Wellington: Wellington Publishing Company, 1915; the Truth about the Slump. Nelson: A. N. Field, 1931, 1932; the Stabilisation of Money. Nelson: A. N. Field: 1934; the Protocols of the Elders of Zion. Nelson: A. N. Field, 1934; the Untaught History of Money. Nelson: A. N. Field, 1938. All These Things, Vol. 1. Nelson: A. N. Field, 1936. Socialism Unmasked. Nelson: A. N. Field, 1938. Why Colleges Breed Communists. Hawthorne, California: Omni Publishing, 1941; the Bretton Woods Plot. Nelson: A. N. Field, 1957. All These Things. Hawthorne, California: Omni Publishing, 1963; the Truth About New Zealand. Bullsbrook: Veritas Books, 1987. ISBN 0-947117-40-7. Marcus La Rooij: "Arthur Nelson Field: Kiwi Theoretician of the Australian Radical Right?" Labour History 89: 37-54. New Zealand Department of External Affairs Archives: Report on Arthur Nelson Field by Security Intelligence Bureau: 15 December 1943: EA1, 84/10/1, Part 1, National Archives.

Paul Spoonley: The Politics of Nostalgia: The Extreme Right in New Zealand: Dunmore Press: Palmerston North: 1987. A. N. Field in libraries

Tropical Park Derby

The Tropical Park Derby is an American Thoroughbred horse race run at Gulfstream ParkHallandale Beach, Florida in mid-December. It is an ungraded stakes race for 3-year-olds with a purse of $75,000 run over the turf at ​1 1⁄16 miles. Prior to 2014, the race was held at Calder Race Course in Florida; the race was once held in early January on New Year’s Day, which made it the first "derby" of the year. In 2011, Calder ran the race twice: once again in October. In 2012 and 2013, it was run in October only. In 2014, the race was run in December. Inaugurated in 1976, the Tropical Park Derby was named for the old Tropical Park Race Track in Miami, it was once thought of as the first step on the American Triple Crown trail. In 2006, Barbaro became the first winner of the race to subsequently win the Kentucky Derby. Due to financial pressure, Calder did not run the race in 2009; the race was downgraded from a Grade III race in 2011 by the American Graded Stakes Committee. The race has been run under the following combinations of distance and surface: ​1 1⁄16 miles on turf - 2014 - present ​1 1⁄8 miles on turf - 1994-2013 ​1 1⁄16 miles on dirt - 1976-1985 ​1 1⁄8 miles on dirt - 1986-1993 2015 - Solemn Tribute 2014 - Sky Flight 2013 - Amen Kitten 2012 - Csaba 2011 - Oligarch 2011 - King Congie 2010 - Fly by Phil 2008 - Cowboy Cal 2007 - Soldier's Dancer 2006 - Barbaro 2005 - Lord Robyn 2004 - Kitten's Joy 2003 - Nothing to Lose 2002‡- Political Attack 2001 - Proud Man 2000 - Go Lib Go 1999 - Valid Reprized 1998 - Draw Again 1997 - Arthur L. 1996 - Ok By Me 1995 - Mecke 1994 - Fabulous Frolic 1993 - Summer Set 1992 - Technology 1991 - Jackie Wackie Calder Race Course official website

Cache Acceleration Software

The Intel Cache Acceleration Software is a computer data storage product for solid-state drive caching. CAS manages using the SSD storage as a cache layer for slower storage data. A cached copy of used data from slower storage is kept in faster SSD storage to improve I/O performance. CAS entered Intel's product line as the result of Intel's August 2012 acquisition of a Canadian start-up company Nevex Virtual Technologies. Versions of Intel CAS are available for Windows Enterprise, Windows Workstation, Linux. CAS for Windows is an application-aware file-based cache, which can be tuned by system administrators. Additionally, it integrates with the operating system's buffer cache, creating a multi-tier cache architecture. CAS is aware of some virtualization technologies like vMotion, maintaining a hot SSD cache during a VM migration. CAS works with the enterprise-class Intel SSD products, such as the DC S3700 SATA drives and the DC P3700 NVMe PCI Express devices, it works with cache devices across SANs.

Intel CAS for Linux consists of a GPL'd source loadable kernel module paired with a closed source user-space admin configuration tool. The CAS for Linux version supports CentOS, Red Hat Enterprise Linux and SUSE Linux Enterprise Server; the Windows Enterprise version runs only on the 64-bit flavors of Windows Server 2008 R2 SP1 and Windows Server 2012 R2. The Windows Workstation version runs on only the 64-bit flavors of Windows 7, Windows 8.1, Windows 10. The current version of CAS for Linux supports write-through, write-back, write-around caching; the Windows versions of CAS support write-back caching. A workstation version, called CAS-W, was announced in September 2013 by Dell. Intel Smart Response Technology for desktop-class computers Microsoft's Automated Tiering Official website Open CAS Framework Old blog post on the Nevex web site explaining the basic idea behind CacheWorks