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Classification and external resources
Specialty gynaecology
ICD-10 N92.1, N92.4
ICD-9-CM 626.6
DiseasesDB 6847
MeSH D008796

Metrorrhagia (metro = measure, -rrhagia = abnormal flow[1]) is uterine bleeding at irregular intervals, particularly between the expected menstrual periods.[2] It is a cause of vaginal bleeding.

In some women, menstrual spotting between periods occurs as a normal and harmless part of ovulation. Some women experience acute mid-cycle abdominal pain around the time of ovulation (sometimes referred to by the German term for this phenomenon, mittelschmerz). This may also occur at the same time as menstrual spotting. The term breakthrough bleeding or breakthrough spotting is usually used for women using hormonal contraceptives, such as IUDs or oral contraceptives, in which it refers to bleeding or spotting between any expected withdrawal bleedings, or bleeding or spotting at any time if none is expected. If spotting continues beyond the first three cycles of oral contraceptive use, a woman should have her prescription changed to a pill containing either more estrogen or more progesterone.[3]

Besides the aforementioned physiologic forms, metrorrhagia may also represent abnormal uterine bleeding and be a sign of an underlying disorder, such as hormone imbalance, endometriosis, uterine fibroids, uterine cancer, or vaginal cancer.

If the bleeding is repeated and heavy, it can cause significant iron-deficiency anemia.


Intermittent spotting between periods can result from any of numerous reproductive system disorders.



Endometrial abnormalities:

Endocrinological causes:

Bleeding disorders:

Drug induced:

Traumatic causes:

Related to pregnancy:

Other causes:

See also[edit]


  1. ^ "Rrhagia | Define Rrhagia at". Retrieved 2013-06-27. 
  2. ^ > Definition of Metrorrhagia Last Editorial Review: 3/17/2003
  3. ^ Carlson, Karen J., MD; Eisenstat, Stephanie A., MD; Ziporyn, Terra (2004). The New Harvard Guide to Women's Health. Harvard University Press. p. 385. ISBN 0-674-01343-3. 

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